Immunology

Jennifer Alexander-Brett, MD, PhD

My research focuses on respiratory immunobiology, with a particular interest in cytokine pathways associated with adult lung epithelial progenitor cells.

Gaya K. Amarasinghe, PhD

Signaling through interferons: Mechanisms and implications for viral pathogenesis and cancer biology

Vivek Arora, MD

My laboratory uses a variety of approaches to discover the molecular events that drive prostate and bladder cancer genesis and progression.

Kareem Azab, PhD

We investigate the mechanisms of neoplasia and metastasis, and develop targeted drug-delivery systems for cancer treatment.

Jeffrey Bednarski, MD, PhD

My lab investigates the signals that regulate early B cell development. Specifically, we are interested in how cellular responses activated by double-strand DNA breaks integrate with normal development processes.

Stephen M. Beverley, PhD

The Beverley Laboratory focuses on the molecular genetics of protozoan parasites, including some of the most deadly pathogens known.

Tarin Bigley, MD, PhD

Viral Immunology, Herpesvirology, Autoimmunity, Immunologic Tolerance

Jacco Boon, PhD

Pathogenesis of Influenza A viruses

Thomas J. Brett, PhD

The molecular basis of lung diseases and drug development using structural biology tools

George J. Broze Jr., MD

Regulation of coagulation, hemostasis

Philip Budge, MD

This laboratory is devoted to research on filarial nematode parasites that cause important diseases in animals and humans (lymphatic filariasis and onchocerciasis), mainly in the tropics.

Thomas P. Burris, PhD

Pharmacology and chemical biology of nuclear receptors.

Jian Campian, MD, PhD

Immunotherapy, brain tumor, spinal cord tumor, high grade gliomas

Aisling Chaney, PhD

pathogenesis of neurodegenerative diseases, inflammation, CNS immune responses, myeloid cell responses

Jaebok Choi, PhD

Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies

Kyunghee Choi, PhD

Cell fate, transcription factors, hematopoiesis, vascular, development, regeneration, stem cells, angiogenesis, tumor

Matthew A. Ciorba, MD

Tryptophan metabolism, intestinal inflammation, colitis associated cancer, colon cancer, mucositis, tryptophan, crohn, colitis, inflammatory bowel disease, radiation enteritis

Megan A. Cooper, MD, PhD

NK cells, interferon gamma IFN-y, autoimmunity, STAT3, immunology, pediatric

Mary C. Dinauer, MD, PhD

Innate immunity, immunodeficiency, inflammation, hematology

Siyuan Ding, PhD

enteric virus infection, innate immune response, intestinal inflammatory signaling

Pirooz Eghtesady, MD, PhD

Analysis of maternal virome and antiviral antibodies to determine the role of viral exposure in the causation of congenital heart disease.

Roberta Faccio, PhD

Arthritis, inflammation, cancer, bone metastases, osteoclasts

Todd A. Fehniger, MD, PhD

Cancer, cytokine, immunology, innate immunity, NK cells, small noncoding RNAs, immunotherapy, lymphoma, genomics

Thomas A. Ferguson, PhD

Angiogenesis, apoptosis, autophagy, immunology, lymphocyte, tolerance, photoreceptors, vision

Francesca Ferraro, MD, PhD

We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.

Daved H. Fremont, PhD

Immunology, virology, structural biology, viral immune evasion, cytokine receptors, signaling, protein trafficking

Misty Good, MD, MS

Necrotizing enterocolitis, prematurity, intestine, immunology, neonatology, pediatrics, infants

Michael J. Holtzman, MD

Innate immunity, macrophages, innate lymphocytes, dendritic cells, epithelial cells, interferon signal transduction, paramyxoviruses, picornaviruses, asthma, drug discovery

Hongzhen Hu, PhD

Neuroimmune mechanisms of sensory processing at barrier surfaces

Shabaana A. Khader, PhD

Tuberculosis, lung, cytokines, host pathogen interactions, immune cells, macrophages, vaccines

Alfred H. J. Kim, MD, PhD

Systemic lupus erythematosus, complement, B cells, mass cytometry, single-cell RNA-seq, experiential renal imaging, sleep quality, social support erosion

Jonathan Kipnis, PhD

We study complex interactions between the immune and nervous systems in health and disease.

Eynav Klechevsky, PhD

Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines

Hrishikesh S. Kulkarni, MD, MSCI

Modulating the complement system to mitigate pneumonia and acute lung injury

Brian Laidlaw, PhD

Development and function of memory B cells in disease states

Kory Lavine, MD, PhD

Cardiology, Cardiovascular Disease, Heart Failure, Transplant

Daniel C. Link, MD

Genomics, hematopoiesis, microenvironment, MicroRNA, neutrophil, stem cells

Gregory D. Longmore, MD

Cell motility, cancer metastasis, cell adhesion, signal transduction

Andrew Malone, MD

Kidney Transplant Single Cell RNAseq

Muhammad Faraz Masood, MD

Endocarditis, heart failure, surgery, medicine, clinical

S. Celeste Morley, MD, PhD

Cell biology of the immune system — understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection

Kenneth Murphy, MD, PhD

Dendritic cells control adaptive immune responses

Rodney Newberry, MD

Immunology, Gastrointestinal Tract, Inflammatory Bowel Disease

Stephen Oh, MD, PhD

Cancer biology, mass cytometry, CyTOF, signal transduction, JAK2, genomics, leukemia, hematopoiesis, stem cells

Eugene M. Oltz, PhD

Cancer, chromatin, epigenetics, genome rearrangements, lymphocytes, transcriptional regulation

Anthony Orvedahl, MD, PhD

Regulation of severe systemic inflammation

Russell K. Pachynski, MD

Tumor immunology, Leukocyte trafficking, Immunotherapy

Michael Paley, MD, PhD

Ocular inflammation, uveitis, scleritis, orbital pseudotumor, mucous membrane pemphigoid

Guangyong Peng, PhD

Role of Senescent T cells in tumor and neurodegeneration; tumor-associated regulatory T cells (Tregs) in suppression of anti-tumor immunity, Toll-like receptor (TLR) ligands and other immunomodulators; metabolic and epigenetic reprogramming of T cells for immunotherapy

David H. Perlmutter, MD

α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs