Developmental, Regenerative & Stem Cell Biology

Sarah Ackerman, PhD

astrocytes, plasticity, circuits, development, myelination

Rajendra S. Apte, MD, PhD

Innate immunity and immune effector mechanisms in the retina; oxidative stress and cell death; models of developmental angiogenesis and neovascularization; inflammation and photoreceptor survival; macular degeneration

Vivek Arora, MD

My laboratory uses a variety of approaches to discover the molecular events that drive prostate and bladder cancer genesis and progression.

Steven Bassnett, PhD

Cell and molecular biology of the ocular lens

Luis F. Z. Batista, PhD

Understanding the importance of telomerase in human stem and progenitor cell function and regulation

Carmen Bergom, MD, PhD

Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury

Paul C. Bridgman, PhD

Cell biology of developing nerve and muscle cells

David M. Brogan, MD, MSc

Nerve injury, nerve regeneration, intra-operatively, mechanisms of inhibiting Wallerian degeneration, Schwann cell dedifferentiation

Andreas H. Burkhalter, PhD

Structure and physiology of neuronal circuits in mouse visual cortex

Valeria Cavalli, PhD

Cellular, Molecular and Epigenetic control of axon regeneration

Douglas L. Chalker, PhD

Chromatin structure, development, DNA, genome rearrangements, RNA interference, transcription

Grant Challen, PhD

Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications

Feng Chen, PhD

genetic determinants and pathogenic mechanisms of urogenital diseases with the goal of improving diagnostic and therapeutic strategies targeting these diseases

Shiming Chen, PhD

Gene expression regulation, transcription factors, epigenetic regulators, photoreceptor development and degeneration, mouse models, gene therapy

Shiming Chen, PhD

Molecular mechanisms regulating photoreceptor gene expression in healthy and diseased retinas

Milan G. Chheda, MD

Understanding epigenetic and genetic mechanisms governing the cancer stem cell state

Kyunghee Choi, PhD

Cell fate, transcription factors, hematopoiesis, vascular, development, regeneration, stem cells, angiogenesis, tumor

F. Sessions Cole, MD

Functional genomics, bioinformatics, pulmonary surfactant, lung development

Jonathan Cooper, PhD

Batten Disease, Neuronal Ceroid Lipofuscinosis, NCL, Lysosomal Storage Disease, pathogenesis, pre-clinical therapies, enzyme replacement, gene therapy

Joseph C. Corbo, MD, PhD

Neurobiology, genomics, transcriptional networks, systems biology, photoreceptors, brain, neuropsychiatric disease, disease, cis-regulation

David Curiel, MD, PhD

development of virus-based therapeutics for inherited and acquired disorders

Zhiyu Dai, PhD

lung vascular biology, cardiopulmonary diseases, single-cell RNA-sequencing, spatial transcriptomics

Aaron DiAntonio, MD, PhD

Axon, endocytosis, nerve regeneration, axon degeneration, neurodegeneration, neuronal development and differentiation, synapse biology, drug screens

Li Ding, PhD

Cancer Proteogenomics and Cancer Models

Eric Greer, PhD

Epigenetics, Transgenerational, Imprinting, Evolution, Multicellularity, Cancer, Tumorigenesis, Epitranscriptomics

Farshid Guilak

osteoarthritis, obesity, mechanobiology and mechanisms of mechanical signal transduction in cartilage, stem-cell therapy

Erik D. Herzog, PhD

Neurobiology, physiology, behavior, imaging, circadian rhythm, olfaction, gliotransmission, brain cancer, potassium channels, computational modeling

Nathaniel Huebsch, PhD

growth factor cell signaling, drug discovery, disease modeling, regenerative medicine

Shin-ichiro Imai, MD, PhD

Understanding the molecular mechanism of aging and longevity in mammals

Masatoshi Inoue, PhD

protein engineering, systems neuroscience, optical molecular tools, neurological disorders

Sanjay Jain, MD, PhD

Development, gene expression, genomics, disease models, Gdnf-Ret signaling, kidney, bladder, innervation, stem cells, organogenesis, nervous system development, translational research

Yoon-A Kang, PhD

Hematopoietic stem cells, Multipotent progenitor, Cell fate decision, Lineage specification

Celeste M. Karch, PhD

Neurodegeneration, neurogenetics, Alzheimer`s disease, frontotemporal dementia, tau, amyloid precursor protein, induced pluripotent stem cells (iPSC), cell and molecular biology, molecular mechanisms

Daniel Kerschensteiner, MD

Imaging, mathematical modeling, neurobiology, physiology, synapse biology, vision

Daniel Kerschensteiner, MD

understand how neural circuits compute behaviorally relevant information: identify the principles and mechanisms that guide the assembly of neural circuits; develop strategies to preserve and restore circuit functions disrupted by disease

Albert H. Kim, MD, PhD

Malignant brain tumors, glioblastoma multiforme, neural stem cells, nervous system development

Ramakrishna Kommagani, PhD

Understanding the cellular, biochemical, and molecular mechanisms that underlie reproductive tract function and its pathology

S. Kerry Kornfeld, MD, PhD

Aging, metals, zinc, development, sperm activation, signal transduction, homeostasis

Kristen L. Kroll, PhD

Epigenetic, neurobiology, embryonic stem cell, neural stem cell, transcription, gene regulatory network, cancer, cell cycle, chromatin, embryo

Spencer Lake, PhD

Musculoskeletal Soft Tissue Mechanics

Kory Lavine, MD, PhD

Cardiology, Cardiovascular Disease, Heart Failure, Transplant

Rebekah Lawrence, PT, PhD

shoulder mechanics, pathology, and function with focus on rehabilitation

Tristan Qingyun Li, PhD

microglia, neuroimmunology, development, aging, neurodegeneration, single cell

Xiaowei Li, PhD

Developing biomaterials platforms for regenerative medicine, with specific interest in applications of biomaterials for angiogenesis and vascularization, stem cell engineering and tissue regeneration.

Irfan J. Lodhi, PhD

Adipose tissue, brown fat, diabetes, obesity, cancer, lipogenesis, lipid metabolism, peroxisomes

Gregory D. Longmore, MD

Cell motility, cancer metastasis, cell adhesion, signal transduction

Liang Ma, PhD

Homeodomain Proteins in Epithelial Differentiation

Susan Mackinnon, MD

Peripheral nerve surgery, nerve transplantation

Muhammad Faraz Masood, MD

Endocarditis, heart failure, surgery, medicine, clinical

Gabriel Mbalaviele, PhD

Inflammation, Inflammasome, NLRP3, Bone, Skeleton, Cytokines