Molecular Genetics & Genomics

Sarah Ackerman, PhD

astrocytes, plasticity, circuits, development, myelination

Hema Adhikari, PhD

oncoprotein signaling networks

Rebecca Aft, MD, PhD

Isolation and characterization of cancer-related genes

Vivek Arora, MD

My laboratory uses a variety of approaches to discover the molecular events that drive prostate and bladder cancer genesis and progression.

Wayne M. Barnes, PhD

Inventing a new way to sequence DNA; PCR at one temp; RT-enabled Taq pol.

Luis F. Z. Batista, PhD

Understanding the importance of telomerase in human stem and progenitor cell function and regulation

Jeffrey Bednarski, MD, PhD

My lab investigates the signals that regulate early B cell development. Specifically, we are interested in how cellular responses activated by double-strand DNA breaks integrate with normal development processes.

Yehuda Ben-Shahar, PhD

We study the evolutionary, genetic, molecular, cellular, and behavioral mechanisms underlying the interaction of animals with their physical and social environments.

Carmen Bergom, MD, PhD

Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury

Stephen M. Beverley, PhD

The Beverley Laboratory focuses on the molecular genetics of protozoan parasites, including some of the most deadly pathogens known.

Joshua Blodgett, PhD

Interdisciplinary questions surrounding bacterial small molecule production

Ryan Bogdan, PhD

How genetic variation and environmental experience contribute to individual differences in brain function, behavior, and psychopathology

Arpita Bose, PhD

Our lab studies microbial metabolisms and their influence on biogeochemical cycling using an interdisciplinary approach.

Michale R. Brent, PhD

Systems biology, transcriptional regulatory networks, network interference, yeast

William Buchser, PhD

We and collaborators seek to understand the biological pathway that controls degeneration and regeneration in these important cells.

Peter M. J. Burgers, PhD

Molecular Biology of DNA replication and damage response in yeast and human

Daniel Castro, PhD

Understanding the biological and psychological mechanisms of endogenous opioids in affect, motivation, and metabolism.

Douglas L. Chalker, PhD

Chromatin structure, development, DNA, genome rearrangements, RNA interference, transcription

Shiming Chen, PhD

Gene expression regulation, transcription factors, epigenetic regulators, photoreceptor development and degeneration, mouse models, gene therapy

Shiming Chen, PhD

Molecular mechanisms regulating photoreceptor gene expression in healthy and diseased retinas

Yao Chen, PhD

Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals

Milan G. Chheda, MD

Understanding epigenetic and genetic mechanisms governing the cancer stem cell state

Malay Choudhury, PhD

Idiopathic pulmonary fibrosis (IPF), metabolic networks, targetable mechanisms driving fibroblast function and fibrosis

Roberto Civitelli, MD

Bone biology, cell adhesion, signal transduction, gap junctions, cadherin

Barak A. Cohen, PhD

Systems biology, enhancers and gene regulatory networks, non-coding genetic variation, computational biology, genomics, quantitative genetics, thermodynamics

Jonathan Cooper, PhD

Batten Disease, Neuronal Ceroid Lipofuscinosis, NCL, Lysosomal Storage Disease, pathogenesis, pre-clinical therapies, enzyme replacement, gene therapy

Joseph C. Corbo, MD, PhD

Neurobiology, genomics, transcriptional networks, systems biology, photoreceptors, brain, neuropsychiatric disease, disease, cis-regulation

Sharon Cresci, MD

Cardiovascular disease, diabetes melitus, genotype, genetic variation

David Curiel, MD, PhD

development of virus-based therapeutics for inherited and acquired disorders

Gautam Dantas, PhD

The Dantas Lab works at the interface of microbial genomics, ecology, synthetic biology, and systems biology, to understand, harness, and engineer the biochemical processing potential of microbial communities.

Patricia Dickson, MD

Developing therapies and studying the impact of lysosomal storage disorders in animal models and in trials

Li Ding, PhD

Cancer Proteogenomics and Cancer Models

Joseph D. Dougherty, PhD

Autism, gene expression profiling, genetics, genomics, mouse models, neurobiology

Susan K. Dutcher, PhD

Signal transduction, centrioles, cilia, human ciliopathies

John R. Edwards, PhD

Bioinformatics, cancer, cancer genomics, epigenetics, epigenomics, transcriptional regulation

Gabor Egervari, PhD

Metabolism, epigenetics, alcohol, addiction, neurodegeneration, Alzheimer’s

Andrea Eveland, PhD

Inflorescence architecture, e.g. the number, length and angle of branches and flowers, is a primary determinant of yield, regulating seed number and harvesting ability.

Francesca Ferraro, MD, PhD

We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.

Harrison W. Gabel, PhD

Exploration of functions for neuron-specific regulators of gene expression, leveraging genes and mechanisms implicated in human neurologic disease to point us toward critical pathways in the brain.

Matthew Goodwin, MD, PhD

Metabolism of cancer, targeting tumor metabolism by blocking metabolic pathways

Abby Green, MD

identify factors within DNA damage response signaling pathways that represent therapeutic vulnerabilities in order to develop new treatment options for children with cancer

Obi L. Griffith, PhD

Bioinformatics, clinical statistics, machine learning, biomarkers, cancer, sequencing, software, databases, genomics, personalized medicine

David H. Gutmann, MD, PhD

Brain cancer, brain development, iPSCs, neural stem cells, glia, genetically-engineered mouse models, learning and behavior, iPSCs, signal transduction, sexual dimorphism

Gabriel Haller, PhD

Genetic underpinnings of multiple neurological/neurosurgical disorders

Michael Hughes, PhD

Our laboratory uses functional genomics to understand tissue specific gene expression in circadian rhythms, skeletal muscle, and lung disease

Shin-ichiro Imai, MD, PhD

Understanding the molecular mechanism of aging and longevity in mammals

Sanjay Jain, MD, PhD

Development, gene expression, genomics, disease models, Gdnf-Ret signaling, kidney, bladder, innervation, stem cells, organogenesis, nervous system development, translational research

Patrick Y. Jay, MD, PhD

Genetics, cardiology

Andreas Kautt

Evolution, Genomics, Animal Behavior, Adaptation, Speciation

Elizabeth A. Kellogg, PhD

We are fascinated by the elegant and diverse forms that plants can take, and we explore the biological basis of this diversity.