Computational & Systems Biology

Berezin Lab research interest lies in the application of optical imaging to understand complex biomedical problems, such as peripheral neuropathies, nerve regenerations, and chronic pain.

• Email: berezinm@wustl.edu

My research program focuses on studying connectivity networks in the human brain using advanced MRI imageanalysis methods

• Email: janine.bijsterbosch@wustl.edu

The interplay between inherited genetic variation, environmental factors, and acquired mutations in shaping the earliest stages of carcinogenesis

• Email: bolton@wustl.edu

Our lab studies microbial metabolisms and their influence on biogeochemical cycling using an interdisciplinary approach.

• Email: abose@wustl.edu

Combining simulation and experiment to understand protein conformational changes, their role in signaling, and opportunities they present for drug design

• Email: bowman@biochem.wustl.edu

Systems biology, transcriptional regulatory networks, network interference, yeast

• Email: brent@cse.wustl.edu

The molecular basis of lung diseases and drug development using structural biology tools

• Email: tbrett@wustl.edu

Nerve injury, nerve regeneration, intra-operatively, mechanisms of inhibiting Wallerian degeneration, Schwann cell dedifferentiation

• Email: brogand@wustl.edu

We study animal communication, sensory processing, and brain evolution

• Email: carlson.bruce@wustl.edu

Understanding the biological and psychological mechanisms of endogenous opioids in affect, motivation, and metabolism.

• Email: castro.d@wustl.edu

Exploring neuromorphic architectures using silicon and biological neurons; Novel self-powered neural recording systems

• Email: shantanu@wustl.edu

Systems biology, enhancers and gene regulatory networks, non-coding genetic variation, computational biology, genomics, quantitative genetics, thermodynamics

• Email: cohen@wustl.edu

Neurobiology, genomics, transcriptional networks, systems biology, photoreceptors, brain, neuropsychiatric disease, disease, cis-regulation

• Email: jcorbo@wustl.edu

Cardiovascular disease, diabetes melitus, genotype, genetic variation

• Email: scresci@wustl.edu

Cardiac arrhythmia, epilepsy, ion channels, drug discovery, molecular biology, kinetic analyses, molecular and kinetic modeling, ultrasound

• Email: jcui@biomed.wustl.edu

The Dantas Lab works at the interface of microbial genomics, ecology, synthetic biology, and systems biology, to understand, harness, and engineer the biochemical processing potential of microbial communities.

• Email: dantas@wustl.edu

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Cancer Proteogenomics and Cancer Models

• Email: lding@wustl.edu

Cytoskeleton, microtubules, molecular motors, optical molecular imaging, plant biology

• Email: ramdixit@wustl.edu

Autism, gene expression profiling, genetics, genomics, mouse models, neurobiology

• Email: jdougherty@wustl.edu

Bioinformatics, cancer, cancer genomics, epigenetics, epigenomics, transcriptional regulation

• Email: jedwards@dom.wustl.edu

Analysis of maternal virome and antiviral antibodies to determine the role of viral exposure in the causation of congenital heart disease.

• Email: eghtesady670@wustl.edu

Anesthetics, photolabeling, mass spectrometry, proteomics

• Email: eversa@wustl.edu

Immunology, virology, structural biology, viral immune evasion, cytokine receptors, signaling, protein trafficking

• Email: fremont@wustl.edu

breast cancer, computational imaging analytics, machine learning, big data, precision medicine

• Email: a.gastounioti@wustl.edu

AAA proteases, cryo-EM, biochemistry, mass spectrometry, structural biology, microbiology, mitochondria

• Email: alirezag@wustl.edu

Maternal-Fetal Immunology; Immunology of pregnancy; Placental Immunology; Neonatal Immunology

• Email: nardhy@wustl.edu

Maternal-Fetal Immunology, Immunology of pregnancy, Placental Immunology, Neonatal Immunology, Obstetrical disorders, Preterm birth, Parturition

• Email: nardhy@wustl.edu

Myosin, actin, single molecule, optical trapping, muscle, cardiac, stem cells, engineered tissue, molecular motors, mechanosensing, cytoskeleton

• Email: greenberg@biochem.wustl.edu

Bioinformatics, clinical statistics, machine learning, biomarkers, cancer, sequencing, software, databases, genomics, personalized medicine

• Email: obigriffith@wustl.edu

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Genetic underpinnings of multiple neurological/neurosurgical disorders

• Email: ghaller@wustl.edu

Immunometabolism, tumor immunology, polyamine transport

• Email: hrichard@wustl.edu

Bacterial pathogenesis, host-pathogen interactions, iron, mass spectrometry, medicinal chemistry, metabolomics

• Email: jhenderson@dom.wustl.edu

Calcium imaging, physiology, mathematical modeling, behavior, neurobiology, smell, olfaction, pheromones, neuroendocrine, circuits

• Email: holy@wustl.edu

Voltage imaging, computational modeling, learning system, memory processing, Drosophila melanogaster

• Email: huang.cheng@wustl.edu

Our laboratory uses functional genomics to understand tissue specific gene expression in circadian rhythms, skeletal muscle, and lung disease

• Email: michael.hughes@wustl.edu

Functional genomics, bioinformatics, human genetics, data science, rare diseases, structural variation

• Email: jin810@wustl.edu

Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines

• Email: eklechevsky@wustl.edu

Biophysics, cardiology, cardiovascular physiology, echocardiography, imaging, mathematical modeling

• Email: sjk@wuphys.wustl.edu

artificial intelligence, machine learning, biomedical imaging, clinical neurosciences

• Email: kundu@wustl.edu

Development and function of memory B cells in disease states

• Email: brian.laidlaw@wustl.edu

Statistical phylogenetics, Bayesian inference, historical biogeography, phenotypic evolution

• Email: michael.landis@wustl.edu

Imaging, molecular imaging, ultrasound, magnetic resonance spectroscopy, drug delivery

• Email: greg.lanza@me.com

DNA recombination, DNA replication, fluorescence, molecular motors, single molecules, thermodynamics

• Email: lohman@biochem.wustl.edu

Non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, epigenetics, cancer

• Email: cmaher@wustl.edu

proteomics, functional genomics, lung cancer, signal transduction, WNT, oxidative stress

• Email: bmajor@wustl.edu

Kidney Transplant Single Cell RNAseq

• Email: amalone@wustl.edu

plant defense optimization, circadian rhythm, tissue type impact

• Email: bmansfeld@wustl.edu

Computational biology, molecular modeling, protein structure, ErbB receptors in oncology, GPCR/G-protein, signal transduction

• Email: garland@biochem.wustl.edu

Endocarditis, heart failure, surgery, medicine, clinical

• Email: masoodm@wudosis.wustl.edu

Epigenetics, Chromatin, Genomics, Gene Regulation, Cell fate, Transcription Factors

• Email: meers@wustl.edu