Computational & Systems Biology

Berezin Lab research interest lies in the application of optical imaging to understand complex biomedical problems, such as peripheral neuropathies, nerve regenerations, and chronic pain.

• Email: berezinm@wustl.edu

My research program focuses on studying connectivity networks in the human brain using advanced MRI imageanalysis methods

• Email: janine.bijsterbosch@wustl.edu

The interplay between inherited genetic variation, environmental factors, and acquired mutations in shaping the earliest stages of carcinogenesis

• Email: bolton@wustl.edu

Our lab studies microbial metabolisms and their influence on biogeochemical cycling using an interdisciplinary approach.

• Email: abose@wustl.edu

Combining simulation and experiment to understand protein conformational changes, their role in signaling, and opportunities they present for drug design

• Email: bowman@biochem.wustl.edu

Systems biology, transcriptional regulatory networks, network interference, yeast

• Email: brent@cse.wustl.edu

The molecular basis of lung diseases and drug development using structural biology tools

• Email: tbrett@wustl.edu

We study animal communication, sensory processing, and brain evolution

• Email: carlson.bruce@wustl.edu

Understanding the biological and psychological mechanisms of endogenous opioids in affect, motivation, and metabolism.

• Email: castro.d@wustl.edu

Exploring neuromorphic architectures using silicon and biological neurons; Novel self-powered neural recording systems

• Email: shantanu@wustl.edu

Liquid biopsy cancer detection

• Email: aadel@wustl.edu

Systems biology, enhancers and gene regulatory networks, non-coding genetic variation, computational biology, genomics, quantitative genetics, thermodynamics

• Email: cohen@wustl.edu

Neurobiology, genomics, transcriptional networks, systems biology, photoreceptors, brain, neuropsychiatric disease, disease, cis-regulation

• Email: jcorbo@wustl.edu

Cardiovascular disease, diabetes melitus, genotype, genetic variation

• Email: scresci@wustl.edu

Cardiac arrhythmia, epilepsy, ion channels, drug discovery, molecular biology, kinetic analyses, molecular and kinetic modeling, ultrasound

• Email: jcui@biomed.wustl.edu

The Dantas Lab works at the interface of microbial genomics, ecology, synthetic biology, and systems biology, to understand, harness, and engineer the biochemical processing potential of microbial communities.

• Email: dantas@wustl.edu

• Twitter

Cancer Proteogenomics and Cancer Models

• Email: lding@wustl.edu

Cytoskeleton, microtubules, molecular motors, optical molecular imaging, plant biology

• Email: ramdixit@wustl.edu

Autism, gene expression profiling, genetics, genomics, mouse models, neurobiology

• Email: jdougherty@wustl.edu

Bioinformatics, cancer, cancer genomics, epigenetics, epigenomics, transcriptional regulation

• Email: jedwards@dom.wustl.edu

Analysis of maternal virome and antiviral antibodies to determine the role of viral exposure in the causation of congenital heart disease.

• Email: eghtesady670@wustl.edu

Anesthetics, photolabeling, mass spectrometry, proteomics

• Email: eversa@wustl.edu

Immunology, virology, structural biology, viral immune evasion, cytokine receptors, signaling, protein trafficking

• Email: fremont@wustl.edu

breast cancer, computational imaging analytics, machine learning, big data, precision medicine

• Email: a.gastounioti@wustl.edu

Myosin, actin, single molecule, optical trapping, muscle, cardiac, stem cells, engineered tissue, molecular motors, mechanosensing, cytoskeleton

• Email: greenberg@biochem.wustl.edu

Bioinformatics, clinical statistics, machine learning, biomarkers, cancer, sequencing, software, databases, genomics, personalized medicine

• Email: obigriffith@wustl.edu

• Twitter

Genetic underpinnings of multiple neurological/neurosurgical disorders

• Email: ghaller@wustl.edu

Bacterial pathogenesis, host-pathogen interactions, iron, mass spectrometry, medicinal chemistry, metabolomics

• Email: jhenderson@dom.wustl.edu

Calcium imaging, physiology, mathematical modeling, behavior, neurobiology, smell, olfaction, pheromones, neuroendocrine, circuits

• Email: holy@wustl.edu

Our laboratory uses functional genomics to understand tissue specific gene expression in circadian rhythms, skeletal muscle, and lung disease

• Email: michael.hughes@wustl.edu

Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines

• Email: eklechevsky@wustl.edu

Biophysics, cardiology, cardiovascular physiology, echocardiography, imaging, mathematical modeling

• Email: sjk@wuphys.wustl.edu

Development and function of memory B cells in disease states

• Email: brian.laidlaw@wustl.edu

Statistical phylogenetics, Bayesian inference, historical biogeography, phenotypic evolution

• Email: michael.landis@wustl.edu

Imaging, molecular imaging, ultrasound, magnetic resonance spectroscopy, drug delivery

• Email: greg.lanza@me.com

DNA recombination, DNA replication, fluorescence, molecular motors, single molecules, thermodynamics

• Email: lohman@biochem.wustl.edu

Non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, epigenetics, cancer

• Email: cmaher@wustl.edu

Kidney Transplant Single Cell RNAseq

• Email: amalone@wustl.edu

Computational biology, molecular modeling, protein structure, ErbB receptors in oncology, GPCR/G-protein, signal transduction

• Email: garland@biochem.wustl.edu

Endocarditis, heart failure, surgery, medicine, clinical

• Email: masoodm@wudosis.wustl.edu

Epigenetics, Chromatin, Genomics, Gene Regulation, Cell fate, Transcription Factors

• Email: meers@wustl.edu

Cell membrane, development, Na K-ATPase, excitable tissue, cell volume

• Email: rmercer@wustl.edu

Synthetic Biology; Systems Biology; Metabolic Engineering; Protein Engineering; Genetic Circuits

• Email: tsmoon@wustl.edu

Autophagy, host-pathogen interactions, infection, tissue regeneration, placenta, ZIKA virus, preterm birth, estrogen

• Email: mysorekari@wudosis.wustl.edu

Ion channel, neurobiology, functional genomics, cell signaling, kinetics

• Email: cnichols@wustl.edu

Ocular inflammation, uveitis, scleritis, orbital pseudotumor, mucous membrane pemphigoid

• Email: paleym@wustl.edu

Huntington’s disease, Polyglutamine Aggregation, Intrinsically Disordered Proteins, Phase transitions in cell biology, Self-assembly, Transcriptional regulation, Small-scale Systems Biology & Interaction Networks

• Email: pappu@wustl.edu

To understand the metabolic crosstalk between cells and tissues in disease models such as cancer by using isotopes and metabolomics

• Email: gjpattij@wustl.edu

Translational Bioinformatics, Clinical Research Informatics

• Email: prpayne@wustl.edu

Genomics, Metabolomics, Aging, Mental Health, CRISPR, Quantified Self, Programming, Systems Biology, Computational Biology, High-Throughput Sequencing

• Email: timrpeterson@wustl.edu