Molecular Cell Biology

Joseph J. H. Ackerman, PhD

biophysics, cancer, imaging, mathematical modeling, neurobiology

Rebecca Aft, MD, PhD

Isolation and characterization of cancer-related genes

Gustav Akk, PhD

Function and modulation of transmitter-gated ion channels

Ream Al-Hasani, PhD

Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.

Ghazaleh Ashrafi, PhD

Uncovering novel regulators of glycolytic and mitochondrial metabolism at the synapse and their role in the pathology of Alzheimer’s disease

Kareem Azab, PhD

We investigate the mechanisms of neoplasia and metastasis, and develop targeted drug-delivery systems for cancer treatment.

Steven Bassnett, PhD

Cell and molecular biology of the ocular lens

Luis F. Z. Batista, PhD

Understanding the importance of telomerase in human stem and progenitor cell function and regulation

Jeffrey Bednarski, MD, PhD

My lab investigates the signals that regulate early B cell development. Specifically, we are interested in how cellular responses activated by double-strand DNA breaks integrate with normal development processes.

Carmen Bergom, MD, PhD

Identification of new targets to improve tumor radiation effectiveness and to protect normal tissues such as the heart from radiation injury

Carlos Bernal-Mizrachi, MD

Novel mechanisms of cardiovascular disease in human and mouse models with insulin resistance and type 2 DM

Kendall J. Blumer, PhD

G protein-coupled receptor signaling in physiology and disease

Ron Bose, MD, PhD

Tyrosine Kinase Signaling in Breast Cancer

Paul C. Bridgman, PhD

Cell biology of developing nerve and muscle cells

Steven Brody, MD

Cell and molecular mechanisms of airway epithelial cell differentiation and cilia biogenesis

Rita Brookheart, PhD

Obesity, diabetes, skeletal muscle, metabolism, cellular stress response

George J. Broze Jr., MD

Regulation of coagulation, hemostasis

Peter M. J. Burgers, PhD

Molecular Biology of DNA replication and damage response in yeast and human

Valeria Cavalli, PhD

Cellular, Molecular and Epigenetic control of axon regeneration

Grant Challen, PhD

Hematopoietic stem cells, Leukemia stem cells, Epigenetic modifications

Aisling Chaney, PhD

pathogenesis of neurodegenerative diseases, inflammation, CNS immune responses, myeloid cell responses

Hong Chen, PhD

Combines biology, engineering, and medicine to develop ultrasound techniques for noninvasive, targeted, and personalized cancer treatment

Yao Chen, PhD

Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals

Wayland W. L. Cheng, MD, PhD

I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.

Milan G. Chheda, MD

Understanding epigenetic and genetic mechanisms governing the cancer stem cell state

Jaebok Choi, PhD

Understanding T cells and immunoregulatory networks in GvHD and GvL for the treatment of hematopoietic malignancies

Kyunghee Choi, PhD

Cell fate, transcription factors, hematopoiesis, vascular, development, regeneration, stem cells, angiogenesis, tumor

Roberto Civitelli, MD

Bone biology, cell adhesion, signal transduction, gap junctions, cadherin

Nicholas O. Davidson, MD

Gene expression, RNA, cancer, mRNA editing, mRNA stability

Albert Davis, PhD, MD

Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies

Brian J. DeBosch, MD, PhD

Cancer metabolism, fasting liver metabolism and caloric restriction mechanisms in diabetes and obesity, mechanistic action of chemotherapy, mitochondrial metabolism, cell signaling

Mary C. Dinauer, MD, PhD

Innate immunity, immunodeficiency, inflammation, hematology

Siyuan Ding, PhD

enteric virus infection, innate immune response, intestinal inflammatory signaling

Abhinav Diwan, MD, FACC, FAHA

Lysosomes, Ischemia-reperfusion, cell death, autophagy, transcriptional regulation, metabolism

Ram Dixit, PhD

Cytoskeleton, microtubules, molecular motors, optical molecular imaging, plant biology

Sergej Djuranovic, PhD

Biochemistry, miRNA, RNA, Ribosome, translation, gene expression, translational control, cancer, malaria

Tamara L. Doering, MD, PhD

Gene regulation, host-pathogen interactions, biochemistry, microbial pathogenesis, pathogenic fungi, yeast, glycobiology, biosynthetic pathways, blood-brain barrier, host response

Susan K. Dutcher, PhD

Signal transduction, centrioles, cilia, human ciliopathies

Gabor Egervari, PhD

Metabolism, epigenetics, alcohol, addiction, neurodegeneration, Alzheimer’s

Pirooz Eghtesady, MD, PhD

Analysis of maternal virome and antiviral antibodies to determine the role of viral exposure in the causation of congenital heart disease.

Sarah K. England, PhD

Women’s health, potassium channels, uterine, muscle excitability, pregnancy

Roberta Faccio, PhD

Arthritis, inflammation, cancer, bone metastases, osteoclasts

Thomas A. Ferguson, PhD

Angiogenesis, apoptosis, autophagy, immunology, lymphocyte, tolerance, photoreceptors, vision

Francesca Ferraro, MD, PhD

We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.

Brian N. Finck, PhD

Identify novel target pathways for therapeutic treatment of obesity-related diseases including diabetes, cardiovascular disease, and fatty liver disease

Antonina Frolova, MD, PhD

High-risk obstetrics, maternal medical conditions complicating pregnancy, preterm birth, abnormal labor

Katherine C. Fuh, MD, PhD

Ovarian cancer, receptor tyrosine kinase signaling, metastasis, EMT, tumor microenvironment

Harrison W. Gabel, PhD

Exploration of functions for neuron-specific regulators of gene expression, leveraging genes and mechanisms implicated in human neurologic disease to point us toward critical pathways in the brain.

Gilbert Gallardo, PhD

Understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in neurodegenerative diseases, including Alzheimer’s disease, by utilizing a combination of biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases.

N. Gautam, PhD

Optogenetic Control of Signaling and Cell Behavior