Immunology

S. Celeste Morley, MD, PhD

Cell biology of the immune system — understanding how cytoskeletal control of cell motility and adhesion impacts host immunity to infection

Kenneth Murphy, MD, PhD

Dendritic cells control adaptive immune responses

Rodney Newberry, MD

Immunology, Gastrointestinal Tract, Inflammatory Bowel Disease

Stephen Oh, MD, PhD

Cancer biology, mass cytometry, CyTOF, signal transduction, JAK2, genomics, leukemia, hematopoiesis, stem cells

Eugene M. Oltz, PhD

Cancer, chromatin, epigenetics, genome rearrangements, lymphocytes, transcriptional regulation

Anthony Orvedahl, MD, PhD

Regulation of severe systemic inflammation

Russell K. Pachynski, MD

Tumor immunology, Leukocyte trafficking, Immunotherapy

Michael Paley, MD, PhD

Ocular inflammation, uveitis, scleritis, orbital pseudotumor, mucous membrane pemphigoid

Hua Pan, PhD

identifying determinant protein domains governing voltage sensing and gate opening mechanisms of the cardiac IKs channel, which is a pathological determinant of the high mortality “Long QT Syndrome”

Guangyong Peng, PhD

Role of Senescent T cells in tumor and neurodegeneration; tumor-associated regulatory T cells (Tregs) in suppression of anti-tumor immunity, Toll-like receptor (TLR) ligands and other immunomodulators; metabolic and epigenetic reprogramming of T cells for immunotherapy

David H. Perlmutter, MD

α1-antitrypsin deficiency, protein secretion, protein degradation, autophagy, proteostasis, autophagy enhancer drugs

Jennifer A. Philips, MD, PhD

Tuberculosis, host-pathogen interactions, innate immunity, autophagy, phagosome maturation, antigen presentation, macrophage, ESCRT

Sumanth Prabhu, MD

Heart failure, cardiomyopathy, heart disease associated with cancer, general cardiology

Gwendalyn Randolph, PhD

lymphatic vessels, lymph nodes, IBD, monocytes, macrophages, high-density lipoprotein, peritoneal tumor metastasis, peritoneal macrophages

Naresha Saligrama, PhD

Adaptive immune responses in neuroinflammatory, neurodegenerative, and neuropsychiatric diseases

Joel D. Schilling, MD, PhD

Macrophage metabolism, cytokine signaling, Toll-Like Receptor (TLR) activation, lysosome dysfunction

Liang Shan, PhD

novel mouse models that contain multiple human gene knock-ins to improve multilineage differentiation of human hematopoietic stem and progenitor cells and development of functional human immune cells in the mouse system

Haina Shin, PhD

Examining immune responses against viruses that establish persistent infections in their hosts

David Sibley, PhD

Cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity

Philip D. Stahl, PhD

Human-specific genes, signal transduction, endocytosis

Christina L. Stallings, PhD

Bacteria, gene regulation, molecular genetics, microbiology, pathogenesis, transcription, infectious disease

Laneshia Karee Tague, MD, MSCI

Our lab investigates immunogenetics and pharmacogenetics in advanced lung disease and lung transplantation

Rui Tang, PhD

cancer metastasis; tumor microenvironment, cancer immunology, CRISPR screen, quantitative biology

Sandeep K. Tripathy, MD, PhD

Innate immunity, NK cells, receptors, signal transduction, tolerance

Aayushi Uberoi, PhD

skin microbiome, skinomics, metagenomics, host-microbial genetics

Deborah Veis, MD, PhD

The Veis lab studies the dynamic regulation of bone cells (osteoclasts and osteoblasts) and bone mass in a variety of normal and disease states, including cancer metastasis, bone infection, and osteoporosis.

Alessandro Vindigni, PhD

DNA replication and repair, genome stability, cancer etiology, chemotherapy response

James Walsh

immune cells and systemic immunity in ocular function, ocular disease

David Wang, PhD

Microbial pathogenesis, functional genomics, virology, genome analysis, computational biology

Jeffrey P. Ward, PhD

Tumor Immunology, Neoantigens, Immunotherapy

Max Wattenberg, MD

Pancreatic cancer, immunotherapy, myeloid cells, CRISPR screening, translational research

Max Wattenberg, PhD

pancreatic cancer, immunotherapy, myeloid cells, tumor microenvironment, CRISPR screening

Sean Whelan, PhD

biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions

Gregory F. Wu, MD, PhD

Antigen presentation, dendritic cells, B cells, immunology, intravital microscopy, multiple sclerosis, neurobiology

Wayne M. Yokoyama, MD

Cancer, immunology, innate immunity, NK cells, tumor biology, virology