Melissa Mavers, MD, PhD
immune regulation of graft-versus-host disease (GVHD), a debilitating and potentially fatal complication of hematopoietic stem cell transplantation (HSCT)
- Email: mmmavers@nospam.wustl.edu
Assistant Professor of Pediatrics
Keywords:
graft-versus-host disease, hematopoietic stem cell transplantation, allogeneic reaction of donor T cells
Research:
The Mavers Lab focuses on immune regulation of graft-versus-host disease (GVHD), a debilitating and potentially fatal complication of hematopoietic stem cell transplantation (HSCT) which arises from an allogeneic reaction of donor T cells to damaged host tissues. HSCT can cure high-risk malignancies and other diseases of the blood and bone marrow, yet success is limited as many patients develop this devastating complication.