Biochemistry, Biophysics & Structural Biology

cancer, optical molecular imaging, molecular probe, near infrared, peptide

• Email: achilefus@mir.wustl.edu

biophysics, cancer, imaging, mathematical modeling, neurobiology

• Email: ackerman@wustl.edu

oncoprotein signaling networks

• Email: hema.adhikari@wustl.edu

Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.

• Email: al-hasanir@wustl.edu

Signaling through interferons: Mechanisms and implications for viral pathogenesis and cancer biology

• Email: gamarasinghe@wustl.edu

We investigate the mechanisms of neoplasia and metastasis, and develop targeted drug-delivery systems for cancer treatment.

• Email: aazab@wustl.edu

Inventing a new way to sequence DNA; PCR at one temp; RT-enabled Taq pol.

• Email: barneswm@wustl.edu

The application of nonlinear dynamics and vibrations to mechanical and biomedical systems

• Email: pvb@wustl.edu

Berezin Lab research interest lies in the application of optical imaging to understand complex biomedical problems, such as peripheral neuropathies, nerve regenerations, and chronic pain.

• Email: berezinm@wustl.edu

The Beverley Laboratory focuses on the molecular genetics of protozoan parasites, including some of the most deadly pathogens known.

• Email: stephen.beverley@wustl.edu

Interdisciplinary questions surrounding bacterial small molecule production

• Email: jblodgett@wustl.edu

G protein-coupled receptor signaling in physiology and disease

• Email: kblumer@wustl.edu

Tyrosine Kinase Signaling in Breast Cancer

• Email: rbose@dom.wustl.edu

Combining simulation and experiment to understand protein conformational changes, their role in signaling, and opportunities they present for drug design

• Email: bowman@biochem.wustl.edu

The molecular basis of lung diseases and drug development using structural biology tools

• Email: tbrett@wustl.edu

Molecular Biology of DNA replication and damage response in yeast and human

• Email: burgers@wustl.edu

Pharmacology and chemical biology of nuclear receptors.

• Email: burristhomas@wustl.edu

Cellular, Molecular and Epigenetic control of axon regeneration

• Email: cavalli@wustl.edu

pathogenesis of neurodegenerative diseases, inflammation, CNS immune responses, myeloid cell responses

• Email: achaney@wustl.edu

molecular mechanisms of opioid receptor signaling, nanobodies, X-ray, Cryo-EM, opioid receptor signaling

• Email: taoche@wustl.edu

Understanding the function of neuromodulators and sleep through the spatiotemporal dynamics of molecular signals

• Email: yaochen@wustl.edu

I am interested in the structure and function of neuronal ligand-gated ion channels, and the mechanism of channel modulation by endogenous lipids or exogenous drugs such as general anesthetics.

• Email: wayland.cheng@wustl.edu

The interface between systems and control engineering, neuroscience and neural medicine

• Email: shinung@WUSTL.EDU

Idiopathic pulmonary fibrosis (IPF), metabolic networks, targetable mechanisms driving fibroblast function and fibrosis

• Email: malay@wustl.edu

Radioluminescence, proton therapy, fiber optics, imaging, microscopy

• Email: arash.darafsheh@wustl.edu

Gene expression, RNA, cancer, mRNA editing, mRNA stability

• Email: nod@wustl.edu

Biochemistry, miRNA, RNA, Ribosome, translation, gene expression, translational control, cancer, malaria

• Email: sergej.djuranovic@wustl.edu

Blood flow, hypoxia, membrane proteins, nitric oxide, redox processes, vascular biology

• Email: doctor@wustl.edu

Gene regulation, host-pathogen interactions, biochemistry, microbial pathogenesis, pathogenic fungi, yeast, glycobiology, biosynthetic pathways, blood-brain barrier, host response

• Email: doering@wustl.edu

Metabolism, epigenetics, alcohol, addiction, neurodegeneration, Alzheimer’s

• Email: gabor@wustl.edu

Immunology, virology, structural biology, viral immune evasion, cytokine receptors, signaling, protein trafficking

• Email: fremont@wustl.edu

Biophysical studies of transcription initiation in Eukaryotes and Mycobacterial tuberculosis

• Email: egalburt@wustl.edu

Optogenetic Control of Signaling and Cell Behavior

• Email: gautam@wustl.edu

AAA proteases, cryo-EM, biochemistry, mass spectrometry, structural biology, microbiology, mitochondria

• Email: alirezag@wustl.edu

Biochemistry, metabolism, parasitology, malaria, protease, heme

• Email: dgoldberg@wustl.edu

Myosin, actin, single molecule, optical trapping, muscle, cardiac, stem cells, engineered tissue, molecular motors, mechanosensing, cytoskeleton

• Email: greenberg@biochem.wustl.edu

Whole Body and Joint-Level Orthopaedic Biomechanics

• Email: harrismi@wustl.edu

Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease

• Email: jhaspel@dom.wustl.edu

Bioinformatics, Proteomic data analysis, Systems biology, Protein redox regulation and structural dynamics

• Email: jheld@wustl.edu

Bacterial pathogenesis, host-pathogen interactions, iron, mass spectrometry, medicinal chemistry, metabolomics

• Email: jhenderson@dom.wustl.edu

Stem cells, differentiation, synapse biology, receptor, ion channel

• Email: jhuettner@wustl.edu

protein engineering, systems neuroscience, optical molecular tools, neurological disorders

• Email: inoue.m@wustl.edu

cancer, metabolism, imaging, sex differences, glioblastoma

• Email: ippolitoj@wustl.edu

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Protein folding and misfolding, and the engineering and application of protein disaggregases to reverse misfolding

• Email: mjackrel@wustl.edu

Organic Chemistry, Biological Chemistry, Organic Synthesis, Protease, lectin, drug discovery, structure-based design, cancer, infectious disease, metastasis, cell-signaling, synthesis, medicinal chemistry, carbohydrate, peptdidomimetic

• Email: janetkaj@wustl.edu

Biochemistry, enzymology, plant biology, protein engineering, protein structure, structural biology

• Email: jjez@biology2.wustl.edu

Cancer, Targeted therapy, Antibodies, Cell signaling, antibody-drug conjugates, drug resistance

• Email: vkapoor@wustl.edu

Aging, metals, zinc, development, sperm activation, signal transduction, homeostasis

• Email: kornfeld@wustl.edu

Biophysics, cardiology, cardiovascular physiology, echocardiography, imaging, mathematical modeling

• Email: sjk@wuphys.wustl.edu

Musculoskeletal Soft Tissue Mechanics

• Email: lake.s@wustl.edu