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SC beta cell differentiation process. Stage 5 Day 2 Pancreatic progenitor cells with depolymerized actin cytoskeleton Microscopic image of insulin-secreting beta cells (insulin is green) that were made from stem cells produced from the skin of a patient with Wolfram syndrome. Stage 6, Day 2 Endocrine progenitor cells Stage 6, Day 8 SC beta cell clusters 24 hours after aggregation Stage 6, Day 11 SC Islets 5x zoom Stage 6, Day 11 SC Islets 20x zoom