Research Interests
- The role of the innate immune system in regulating pathologic angiogenesis
- The effects of senescence and physiologic aging on macrophage gene regulation
- Oxidative stress, inflammation and the regulation of cell death in models of macular degeneration
- Regulation of photoreceptor cell death by inflammation
- The role of innate immune cells in aging and disease
- Molecular regulation of uveitis
- The role of microRNAs in aging and age-related eye pathologies
- Molecular mechanisms in retinal microglia contributing to eye pathologies
- The role of cholesterol transport in models of ocular disease
- Therapeutic interventions for dry eye disease



Lab News
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1-23-25: “The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases” by Joseph B. Lin and Rajendra S. Apte is now available in Investigative Ophthalmology & Visual Sciences
12-17-24: Mitsu Yoshida, MD, PhD has received a research fellowship award from VRSF for AMD research
12-17-24: Post-doctoral research fellow Taku Yamamoto, MD, PhD has received a VRSF award for research on Aging and Ocular Immunity
12-5-24: Henok Getahun has been awarded the RPB medical student Eye Research Fellowship
11-4-24: Congratulations to Jason Colasanti on the successful defense of his PhD thesis “The Role of MiR-34a in Pathological Neovascularization as Seen in Age-Related Macular Degeneration”.
10-16-24: Congratulations, Poonam Naik on being named a Center for Regenerative Medicine(CRM) Distinguished Postdoc Scholar!
8-21-24: New publication from lead author Ryo Terao “Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration” is available now in IOVS.
8-1-2024: Welcome new post-doc, Poonam Naik!
7-8-2024: Welcome new post-doc, Nori Misawa!
