Research Interests

  • The role of the innate immune system in regulating pathologic angiogenesis
  • The effects of senescence and physiologic aging on macrophage gene regulation
  • Oxidative stress, inflammation and the regulation of cell death in models of macular degeneration
  • Regulation of photoreceptor cell death by inflammation
  • The role of innate immune cells in aging and disease
  • Molecular regulation of uveitis
  • The role of microRNAs in aging and age-related eye pathologies
  • Molecular mechanisms in retinal microglia contributing to eye pathologies
  • The role of cholesterol transport in models of ocular disease
  • Therapeutic interventions for dry eye disease


Lab News

Follow us:

1-23-25: “The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases” by Joseph B. Lin and Rajendra S. Apte is now available in Investigative Ophthalmology & Visual Sciences

12-17-24: Mitsu Yoshida, MD, PhD has received a research fellowship award from VRSF for AMD research

12-17-24: Post-doctoral research fellow Taku Yamamoto, MD, PhD has received a VRSF award for research on Aging and Ocular Immunity

12-5-24: Henok Getahun  has been awarded the RPB medical student Eye Research Fellowship

11-4-24: Congratulations to Jason Colasanti on the successful defense of his PhD thesis “The Role of MiR-34a in Pathological Neovascularization as Seen in Age-Related Macular Degeneration”.

10-16-24: Congratulations, Poonam Naik on being named a Center for Regenerative Medicine(CRM) Distinguished Postdoc Scholar!

8-21-24: New publication from lead author Ryo Terao “Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration” is available now in IOVS.

8-1-2024: Welcome new post-doc, Poonam Naik!

7-8-2024: Welcome new post-doc, Nori Misawa!

6-7-2024: Joseph Lin has been awarded the 2024 Cecil M. DeGutis Prize . This award recognizes one graduate student each year for research excellence and dedication to the fields of medicinal chemistry or chemical biology.  Congratulations, Joseph!