Research Interests
- The role of the innate immune system in regulating pathologic angiogenesis
- The effects of senescence and physiologic aging on macrophage gene regulation
- Oxidative stress, inflammation and the regulation of cell death in models of macular degeneration
- Regulation of photoreceptor cell death by inflammation
- The role of innate immune cells in aging and disease
- Molecular regulation of uveitis
- The role of microRNAs in aging and age-related eye pathologies
- Molecular mechanisms in retinal microglia contributing to eye pathologies
- The role of cholesterol transport in models of ocular disease
- Therapeutic interventions for dry eye disease
Lab News
Follow us:
10-16-24: Congratulations, Poonam Naik on being named a Center for Regenerative Medicine(CRM) Distinguished Postdoc Scholar!
8-21-24: New publication from lead author Ryo Terao “Cholesterol Accumulation Promotes Photoreceptor Senescence and Retinal Degeneration” is available now in IOVS.
8-1-2024: Welcome new post-doc, Poonam Naik!
7-8-2024: Welcome new post-doc, Nori Misawa!
6-7-2024: Joseph Lin has been awarded the 2024 Cecil M. DeGutis Prize . This award recognizes one graduate student each year for research excellence and dedication to the fields of medicinal chemistry or chemical biology. Congratulations, Joseph!
6-6-2024: Tim Lee, PhD, has been named the 2024 Postdoctoral Winston Fellow. Congratulations, Tim!
4-17-2024: New publication in Cell Reports from lead author Ryo Terao, MD, PhD, “LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion.“
