Cross-sectional MRLongitudinal MRI Data in Nondemented and Demented Older AdultsI Data in Young, Middle Aged, Nondemented and Demented Older Adults


This set consists of a longitudinal collection of 150 subjects aged 60 to 96. Each subject was scanned on two or more visits, separated by at least one year for a total of 373 imaging sessions. For each subject, 3 or 4 individual T1-weighted MRI scans obtained in single scan sessions are included. The subjects are all right-handed and include both men and women. 72 of the subjects were characterized as nondemented throughout the study. 64 of the included subjects were characterized as demented at the time of their initial visits and remained so for subsequent scans, including 51 individuals with mild to moderate Alzheimer’s disease. Another 14 subjects were characterized as nondemented at the time of their initial visit and were subsequently characterized as demented at a later visit.


MR Sessions

Publications and Acknowledgements


Acknowledgments: “Data were provided [in part] by OASIS [insert appropriate OASIS source info]”

OASIS-2: Longitudinal: Principal Investigators: D. Marcus, R, Buckner, J. Csernansky, J. Morris; P50 AG05681, P01 AG03991, P01 AG026276, R01 AG021910, P20 MH071616, U24 RR021382


Open Access Series of Imaging Studies (OASIS): Longitudinal MRI Data in Nondemented and Demented Older Adults. Marcus, DS, Fotenos, AF, Csernansky, JG, Morris, JC, Buckner, RL, 2010. Journal of Cognitive Neuroscience, 22, 2677-2684. doi: 10.1162/jocn.2009.21407

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OASIS-2 Longitudinal Subject Data

The following links contain important information on OASIS-2 subjects and processing.

Demographic Data

OASIS-2 Longitudinal Scan Data

OASIS-2 Longitudinal image data is available at the following links.