2023
Sen P, Donahue G, Li C, Lan Y, Egervari G, Robertson N, Shah P, Kerkhoven E, Schultz D, Adams P, Berger SL. Spurious intragenic transcription is a hallmark of mammalian cellular senescence and tissue aging. Nature Aging, 2023 Mar;3:402-417
2022
Alexander DC, Corman T, Mendoza M, Glass A, Belity T, Campbell R, Han J, Keiser A, Winkler J, Wood MA, Kim T, Garcia BA, Cohen H, Mews P#, Egervari G#, Berger SL#. Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation. Proceedings of the National Academy of Sciences, 2022 Aug 9;119(32):e2114758119.
Dmitrieva-Posocco O, Wong AC, Lundgren P, Golos AM, Descamps HC, Dohnalova L, Cramer Z, Tian Y, Yueh B, Eskiocak O, Egervari G, Lan Y, Liu J, Fan J, Kim J, Madhu B, Schneider KM, Khoziainova S, Andreeva N, Wang Q, Li N, Furth EE, Bailis W, Kelsen JR, Hamilton KE, Kaestner KH, Berger SL, Epstein JA, Jain R, Li M, Beyaz S, Lengner CJ, Katona BW, Grivennikov SI, Thaiss CA, Levy M. Beta-hydroxybutyrate suppresses colorectal cancer. Nature, 2022 May;605(7908):160-165
Mendoza M*, Egervari G*#, Donahue G, Sidoli S, Alexander DC, Sen P, Garcia BA#, Berger SL#. Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites. Science Advances, 2022 Jan 21;8(3):eabj5688.
2021
Egervari G#, Siciliano CA#, Whiteley E, Ron D#. Alcohol and the brain: from genes to circuits. Trends in Neurosciences, 2021 Dec;44(12):1004-1015
Egervari G#. Chromatin accessibility in neuropsychiatric disorders. Neurobiology of Learning and Memory, 2021 May;181:107438
2020
Egervari G, Glastad KM, Berger SL. Food for thought. Science, 2020 Nov;370(6517):660-662
Egervari G, Akpoyibo D, Rahman T, Fullard JF, Callens JE, Landry JA, Ly A, Zhou X, Warren N, Hauberg M, Hoffmann G, Ellis R, Ferland JN, Miller ML, Keller E, Zhang B, Roussos P, Hurd YL. Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder. Nature Communications, 2020 Sep 14;11(1):4634
Michaelides M, Miller ML, Egervari G, Primeaux SD, Gomez JL, Ellis RJ, Landry JA, Szutorisz H, Hoffman AF, Lupica CR, Loos RJF, Thanos PK, Bray GA, Neumaier JF, Zachariou V, Wang GJ, Volkow ND, Hurd YL. Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity. Molecular Psychiatry 2020 Sep;25(9):2058-2069
2019
Mews P*, Egervari G*#, Nativio R, Sidoli S, Donahue G, Lombroso SI, Alexander DC, Riesche SL, Heller EA, Nestler EJ, Garcia BA, Berger SL#. Alcohol metabolism contributes to brain histone acetylation. Nature, 2019 Oct;574(7780):717-721
Egervari G, Kozlenkov A, Dracheva S, Hurd YL. Molecular windows into the human brain for psychiatric disorders. Molecular Psychiatry 2019 May;24(5):653-673
Miller ML, Chadwick B, Dickstein D, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P, Shen L, Baxter M, Hurd YL. Adolescent exposure to d9-tetrahydrocannabinol alters the transcriptional projectory and dendritic architecture of prefrontal pyramidal neurons. Molecular Psychiatry, 2019 Mar;24(4):588-600
2018
Xi L*, Egervari G*, Wang Y, Berger SL, Lu Z. Regulation of chromatin and gene expression by metabolic enzymes and metabolites. Nature Reviews Molecular Cell Biology 2018 Sep;19(9):563-578
Fullard JF, Hauberg ME, Bendl J, Egervari G, Cirnaru MD, Reach SM, Motl J, Ehrlich ME, Hurd YL, Roussos P. An atlas of chromatin accessibility in the adult human brain. Genome Research, 2018 Aug;28(8):1243-1252
Miller ML, Ren Y, Szutorisz H, Warren N, Tessereau C, Egervari G, Mlodnicka A, Chaarani B, Morris C, Schumann G, Garavan H, Bannon M, Halperin J, Kapoor M, Goete A, Hurd YL. Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. Molecular Psychiatry, 2018 May;23(5):1328-1335
Egervari G, Ciccocioppo R, Jentsch JD, Hurd YL. Shaping individual addiction vulnerability – the contribution of behavior, neural circuits and molecular mechanisms. Neuroscience and Biobehavoral Reviews, 2018 Feb;85:117-125
2017
Michaelides M, Miller ML, DiNieri JA, Gomez JL, Schwartz E, Egervari G, Wang GJ, Mobbs CV, Volkow ND, Hurd YL. Dopamine D2 receptor signaling in the nucleus accumbens comprises a metabolic-cognitive brain interface regulating metabolic components of glucose reinforcement. Neuropsychopharmacology, 2017 Nov;42(12):2365-2376
Egervari G#, Rahman T. Increased firing of lateral habenula neurons mediates ethanol aversion – potential implications for substance use disorders. Journal of Physiology, 2017 Jul 1;595(13):4135-4136
Egervari G, Landry J, Callens J, Fullard JF, Roussos P, Keller E, Hurd YL. Striatal H3K27 acertylation linked to glutamatergic gene dysregulation in human heroin abusers holds promise as therapeutic target. Biological Psychiatry 2017 Apr 1;81(7):585-594
2016
Szutorisz H, Egervari G, Sperry J, Carter JM, Hurd YL. Cross-generational THC exposure alters the developmental sensitivity of ventral and dorsal striatal gene expression in male and female offspring. Neurotoxicology and Teratology 2016 Nov – Dec;58:107-114
Egervari G#. AMPA receptor plasticity in the nucleus accumbens mediates withdrawal-related negative-affective states. Journal of Neuroscience, 2016 Oct 12;36(41):10505-10507
Egervari G*, Jutras-Aswad D*, Landry J, Miller ML, Anderson SA, Michaelides M, Jacobs MM, Peter C, Yiannoulos G, Liu X, Hurd YL. A functional 3’UTR polymorphism (rs2235749) of prodynorphin alters microRNA-365 binding in ventral striatonigral neurons to influence novelty seeking and positive reward traits. Neuropsychopharmacology 2016 Sep;41(10):2512-2520
2015
Koo JW, Mazei-Robison MS, LaPlant Q, Egervari G, Braunscheidel KM, Adank DN, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno DM, Ribeiro E, Peña CJ, Walker D, Bagot RC, Cahill ME, Anderson SA, Labonté B, Hodes GE, Browne H, Chadwick B, Robison AJ, Vialou VF, Dias C, Lorsch Z, Mouzon E, Lobo MK, Dietz DM, Russo SJ, Neve RL, Hurd YL, Nestler EJ. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nature Neuroscience 2015 Mar;18(3):415-22
2014
Szutorisz H, DiNieri, JA, Sweet E, Egervari G, Michaelides M, Carter JM, Ren Y, Miller ML, Blitzer RD, Hurd YL. Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation. Neuropsychopharmacology 2014 May;39(6):1315-23
2011
Egervari G*, Mark A*, Hajdu M, Barna G, Sapi Z, Krenacs T, Kopper L, Sebestyen A. Mitotic lymphoma cells are characterized by high expression of phosphorylated ribosomal S6 protein. Histochemistry and Cell Biology 2011 Apr;135(4):409-17