May 13, 2024: Best of luck to our graduating seniors moving onto great things!

Allan is moving to Caltech to pursue his PhD in Biochemistry!
Amy is moving to Tufts to pursue her PhD in Chemistry!
Cynthia is moving to Harvard to pursue her PhD in Chemical Biology!
Ken is joining the MSTP program at Yale to pursue his MD/PhD!

May 6, 2024: Chris Camitta joins the lab as a graduate student!! Welcome Chris!

May 1, 2024: Our senior undergraduates were honored at our annual department luncheon with a number of awards:
Ken received the American Chemical Society Biochemistry Award
Allan and Amy received the Royal Society of Chemistry Merck Index Award
Cynthia received the Lipkin Award for Bioorganic Chemistry

Congratulations everyone!!

April 26, 2024: Following graduation, Sheng has moved onto a position at Purohit Navigation as a junior strategic analyst!

April 4, 2024: Darcy has been awarded a National Science Foundation Graduate Research Fellowship (NSF-GRFP), and Cynthia received an honorable mention!

March 18, 2024: Sheng’s paper is published in Nature Communications!!

February 23, 2024: Following graduation, Jeremy has moved on to a post-doc position at Bayer!

January 22, 2024: Jeremy defended his Ph.D. thesis!

December 4, 2023: Sheng defended his Ph.D. thesis!

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November 3, 2023: Meredith presented a Neurology/Neuroscience seminar at the University of Michigan, which was jointly sponsored by the LiveLikeLou Foundation.

October 10, 2023: Macy defended her Ph.D. thesis!

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September 25, 2023: Collaborative work with Ying Chen’s lab has been accepted at Nature Communications. Preprint link

August 24, 2023: Our work on the HtrA1 disaggregase has been preprinted on Research Square!

August 10, 2023: Meredith presented an invited seminar at the Packard Center for ALS Research at Johns Hopkins University.

August 9, 2023: Collaborative work with the Rudra Lab is accepted for publication in Acta Biomaterialia! 

June 8, 2023: Meredith gave a talk at the Proteostasis Research in Canada (PRINCE) 2023 meeting.

June 1, 2023: Darcy Harris joins the lab as a graduate student! Darcy will work jointly between our lab and the Rudra Lab.

May 31, 2023: Cynthia is named a Beckman Scholar!

May 17, 2023: Our work to model Staph biofilm protein properties in yeast, where we also show that Hsp104 can dissolve biofilms, is published in mBio!

May 3, 2023: Brian is awarded the Sowden Prize for the top graduating senior!

May 3, 2023: Shamika is awarded the Royal Society of Chemistry Merck Index Award at graduation!

March 31, 2023: Ken has been named a Goldwater Scholar!

March 29, 2023: Joey has been awarded a National Science Foundation Graduate Research Fellowship (NSF-GRFP)!

March 25, 2023: Kira has been named a MARC U-STAR fellow, which will support her work in the lab from 2023 to 2025!

March 1, 2023: Anirban Das joins the lab as a postdoctoral researcher! Anirban will work jointly between our lab and the Rudra Lab in Biomedical Engineering.

January 12, 2023: Collaborative work with Maggie Chen’s lab on protein misfolding in kidney disease is preprinted at BioRxiv.

January 1, 2023: R21 proposal on liquid-liquid phase separation of Matrin-3 is funded by National Institute on Aging (NIA).

January 1, 2023: Joey starts his graduate studies in the lab!

November 12, 2022: Ken gave a presentation at the ABRCMS annual meeting and received a presentation award for his work!

October 20, 2022: Meredith gave the keynote lecture at the University of Michigan Protein Folding Diseases Initiative Symposium.

October 15, 2022: Jeremy won a poster prize at the Biochemistry, Biophysics, & Structural Biology retreat!

October 14, 2022: Meredith gave a talk and the lab presented posters at the inaugural symposium for the Center for Biomolecular Condensates at WUSTL.

September 12, 2022: Our latest work on amyloid-inspired peptides as vaccine materials in collaboration with the Rudra Lab is posted on BioRxiv.

August 1, 2022: Anuradhika is awarded the ALS Association’s Milton Safenowitz Postdoctoral Fellowship!

July 15, 2022: Macy and Meredith attended a forum organized by the Live Like Lou Foundation, where Macy presented a poster and Meredith presented a talk.

July 1, 2022: Macy’s methods paper is accepted for publication in STAR Protocols!

May 31, 2022: Kira Jones joins the lab as a uSTAR Summer Scholar!

April 26, 2022: Jeremy, Macy, and Meredith attended the Protein Homeostasis in Health and Disease Conference at Cold Spring Harbor, where Jeremy and Macy presented posters and Meredith presented a seminar.

April 5, 2022: Brian has been awarded a BioSURF fellowship to support his work over the summer!

March 25, 2022: Ken has been named a MARC U-STAR fellow, which will support his work in the lab from 2022 to 2024!

March 14, 2022: Brian Sohn has been selected as the winner of the Washington University Outstanding Junior Award, which is sponsored by the St. Louis ACS Section!

February 4, 2022: Our work on Matrin-3 and its role in driving ALS is accepted for publication in iScience!

January 18, 2022: Avika Jayatilaka joins the lab as a graduate student!

January 4, 2022: Sabrina Talir joins the lab as a research assistant!

November 1, 2021: Anuradhika Puri joins the lab as a postdoctoral researcher!

August 1, 2021: Our work in collaboration with the Rudra Lab on amyloid-inspired vaccine delivery for the elderly is funded by the National Institute on Aging!

July 14, 2021: Joey Fritsche and Andy Xu join the lab as research specialists!

July 11, 2021: Macy’s review of prion-like proteins is published in Biomolecules.

July 9, 2021: Best of luck to Matt, as he heads off to pursue his Ph.D. at UCSF!

June 30, 2021: Congratulations to Jeremy, who has been awarded an NIH NRSA Fellowship from the National Institute of General Medical Sciences (NIGMS)!

May 28, 2021: Best of luck to Braxton, as he heads off to pursue his Ph.D. in Chemistry at Stanford!

May 21, 2021: Best of luck to Cendi, as she heads off to pursue her Ph.D. at UCLA!

May 19, 2021: Our work on scanning mutagenesis of Hsp104 is accepted for publication in Protein Science!

May 19, 2021: Cendi was awarded the Lipkin Memorial Prize for Organic or Bio-organic Chemistry!

January 22, 2021: Macy has been awarded an NIH NRSA Fellowship from the National Institute of Neurological Disorders and Stroke (NINDS)!

July 1, 2020: Meredith was awarded a Career Development Award from the American Heart Association!

May 13, 2020: Braxton was awarded the Lipkin Memorial Prize for Organic or Bio-organic Chemistry!

May 13, 2020: Andy was awarded the Merck Index Award for special achievements in the Chemical Sciences!

March 10, 2020: Our work on Hsp104 is published in PLoS ONE. Congratulations Matt, Brian, Julius, and Andy!

February 18, 2020: Meredith presents a talk and co-chairs the Protein Stability, Folding, and Chaperones platform session for the Biophysical Society Annual Meeting.

January 10, 2020: Karlie Miller joins the lab as a graduate student!

November 1, 2019: The ALS Association has awarded us a research grant!

October 31, 2019: Meredith presents an invited seminar at Middle Tennessee State University’s Molecular Biosciences Seminar Series

October 13, 2019: Macy and Jeremy present posters at the American Neurological Association Annual Meeting!

September 23, 2019: Rachel Dreher joins the lab as a research specialist.

August 8, 2019: Macy’s Preview is published in Molecular Cell!

July 1, 2019: Jeremy is named a Center for Science & Engineering of Living Systems (CSELS) Graduate Scholar!

June 5, 2019: Our work on sarcoma is accepted for publication in J. Biol. Chem. Congratulations Jeremy, Macy, and Kayla!

May 1, 2019: The Knight Alzheimer’s Disease Research Center has awarded us a pilot grant!

May 1, 2019: Matt was awarded the Lipkin Award for Organic or Bio-organic Chemistry!

May 1, 2019: Meredith presents a talk at the Target ALS meeting in Boston.

April 5, 2019: Cendi and Jessica were awarded BioSURF fellowships to support their work over the summer!

March 15, 2019: Andy Chen joins the lab as a graduate student!

October 8, 2018: Meredith presents a seminar at the Department of Chemistry and Biochemistry at University of Missouri – St. Louis.

October 1, 2018: The Longer Life Foundation has awarded us a grant!

September 4, 2018: Maurie Balch joins the lab as a postdoctoral researcher!

August 26, 2018: Meredith presents an invited talk at the LiveLikeLou Foundation symposium in Pittsburgh.

August 26, 2018: Macy presents a poster at the LiveLikeLou Foundation symposium in Pittsburgh.

August 1, 2018: The Lab is awarded an R35 MIRA from the National Institute Of General Medical Sciences!

June 11, 2018: Kayla Holthaus joins the lab as a research specialist!

April 18, 2018: Meredith presents research at the Cold Spring Harbor Protein homeostasis in health and disease meeting.

April 10, 2018: Jeremy and Macy present posters at the Washington University Hope Center retreat.

April 9, 2018: Matt is awarded a BioSURF fellowship to support his work!

April 7, 2018: Aaron is awarded a uSTAR scholarship to support his work!

April 2, 2018: Meredith presents a seminar at the Edward A. Doisy Department of Biochemistry and Molecular Biology at Saint Louis University School of Medicine. Thanks to Yuna Ayala for hosting!

December 5, 2017: The Frick Foundation for ALS Research has awarded us a grant!

December 4, 2017: Meredith presents a talk in the “Protein Folding, Misfolding, and Neurodegeneration” minisymposium at the ASCB|EMBO 2017 meeting in Philadelphia.

October 1, 2017: The ALS Association has awarded us a grant to explore the effects of Hsp104 variants on TDP-43, FUS, and dipeptide repeat proteins!

August 1, 2017: The lab opens!