Jeremy is a graduate student in the lab. He graduated from Drury University in 2017 with a B.S. in Biology and a B.A. in Chemistry. He is originally from Camdenton, Missouri. When he is not in the lab he enjoys running, biking, and spending time outdoors. In 2019, Jeremy was named a Center for Science & Engineering of Living Systems (CSELS) Graduate Scholar. In 2021 Jeremy was awarded an NIH NRSA Fellowship from the National Institute of General Medical Sciences (NIGMS). Jeremy graduated in 2024 and went on to a post-doc position at Bayer in St. Louis.
Publications:
Chen S, Puri A, Bell B, Fritsche J, Palacios HH, Balch M, Sprunger ML, Howard MK, Ryan JJ, Haines JN, Patti GJ, Davis AA, and Jackrel ME (2024). HTRA1 disaggregates α-synuclein amyloid fibrils and coverts them into non-toxic and seeding incompetent species. Nat. Commun. 15: 2436. link
Howard, M.K., Miller K.R., Sohn B.S., Ryan J.J., Xu A., and M.E. Jackrel^ (2023). Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases. mBio. 10.1128/mbio.00587-23 (^Corresponding author) pdf file link
Ryan, J.J., A. Bao, B. Bell, C. Ling, and M.E. Jackrel (2021). Drivers of Hsp104 potentiation revealed by scanning mutagenesis of the middle domain. Protein Science. 30(8):1667-1685. pdf file link
Ryan, J.J., M.L. Sprunger, K. Holthaus, J. Shorter and M.E. Jackrel. (2019). Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. J. Biol. Chem. doi: 10.1074/jbc.RA119.009494. pdf file link.