About the mentor:
Jing Hughes, MD PhD: Assistant Professor of Medicine at Washington University since 2019. I have trained undergraduates, graduate students, postdoctoral fellows, clinical fellows, and visiting scientists in my lab. I am passionate about teaching and fostering careers in academic medicine. I consider mentoring the most important part of my job.
Lab mentoring plan and structured training activities. Trainees in the Hughes Lab will receive guidance from the PI and senior lab members on:
- Experimental design
- Data analysis and interpretation
- Manuscript and grant writing
- Scientific data integrity
- Written and oral communication skills
Core techniques used in the lab include:
- Rodent surgery and pancreatic islet isolation
- Tissue culture and islet function testing
- Western blotting, RNA isolation, quantitative PCR, ELISA
- Transmission and scanning electron microscopy
- Quantitative fluorescence microscopy, live-cell imaging
- MATLAB data analysis
The lab holds frequent social outings and team-building events. We emphasize rest and time away from lab for mental and physical well-being.
The PI’s office is in the lab space and has an open-door policy. We do informal check-ins with everyone daily. We also hold structured one-on-one meetings (30-60 min) and lab meetings (60-90 min) weekly. All trainees have the opportunity to present within the institution and at national/international conferences. Everyone will meet with the PI for formal feedback on research and career development at least annually. Ethics training will be conducted via School of Medicine courses and regular discussions within the lab.
The PI will promote trainee success by publishing their work in a timely manner, supporting their grant applications, facilitating professional networking, and recommending them for awards and speaking opportunities. Individualized learning opportunities including mini-sabbaticals at collaborator labs and conference travel are covered by the lab.
The PI holds a clinical appointment with Barnes-Jewish Hospital and offers shadowing experiences to those interested on the inpatient and outpatient endocrine services.
Resources and support. Our newly renovated lab occupies 1,200 sq ft of wet lab space on the 8th floor of Southwest Tower in Barnes-Jewish Hospital, with shared equipment with other labs in the Endocrine Division and Diabetes Research Center. Most of our imaging is done at the Washington University Center for Cellular Imaging (WUCCI).
Specific for postdocs: commitment to trainee careers and plans for transitioning to independence. The PI will work with each postdoctoral trainee to develop their path to independence via the following milestones:
- Manuscript publications
- Identifying and obtaining intramural funding through the Washington University Diabetes Research Center (DRC), T32 training grant, WUCCI project seed grants, and Institute of Clinical and Translational Sciences (ICTS)
- Extramural funding through NIH K awards and foundation grants
- Discussion about division and ownership of research projects
- Tools, reagents, and projects developed by each postdoc will be theirs to take to implement their independent research career. This is a promise from the start, to allow the necessary freedom to pursue new and creative research directions.