


Our Focus
The Hughes lab at Washington University studies primary cilia, whose function as a cellular sensor and signaling hub underlies islet hormone secretion and cell-cell interactions. Metabolic diseases such as diabetes and obesity are influenced by primary cilia in many ways, which we are studying using imaging and cell biology approaches:
- multi-modal microscopy
- live-cell sensors
- animal models of ciliopathy
- metabolic phenotyping
- proteomics
- transcriptomics
Contact Us
Hughes Lab
815 Southwest Tower, Barnes-Jewish Hospital
Washington University School of Medicine
(314) 362-7878
Affiliations:
Division of Endocrinology, Metabolism & Lipid Research