Faculty

Abdallah’s Pubmed.

Abdallah’s research interests lie in the field of Bioinformatics and Computational Biology. More specifically, he is interested in the development of computational algorithms and machines learning approaches to integrate and interpret multiple large-scale modalities of “omics” data to better understand the biology of multiple neurodegenerative diseases with more emphasis on Alzheimer’s disease.

I have the privilege of leading a multicultural and diverse multidisciplinary research group that brings together computational biologists, systems biologists, and bioinformaticians to study Alzheimer disease, related dementias and neurodegeneration. We use traditional statistical and advanced machine learning and data science approaches to analyze molecular data and provide novel insights on neurodegeneration.

Our work aims to discern how genetic factor and genes contribute to the biological processes that affect disease using multi-omic integrative approaches with particular emphases in single-cell molecular data and spatially resolved transcriptomics. We develop and use innovative analytical workflows to study the genetic, transcriptomic, proteomic, metabolomic, and epigenetic data from tissue homogenates and single-cell brain tissue.

Dr. Harari PubMed Page.

Carolina’s Pubmed.

Carolina is a biologist with a PhD in Genetics from the Autonomous University of Barcelona and a M.S. in Bioinformatics and Biostatistics from Open University of Catalonia (Spain).

Her research interests focus on epigenetics, genetics , single-cell RNA sequencing and multi-omic approaches to identify novel variants, genes and pathways implicated on aging-associated diseases, with special attention to Stroke and Alzheimer’s disease. Her interests are also in the field of epigenetics of aging. To achieve her objectives she combines different tools: large and well characterized human cohorts, next generation sequencing (e.g. GWAS, EWAS, exome sequencing, single-cell RNAseq), bioinformatics, biostatistics and omic-data integration. She is fascinated by how epigenetic mechanism might modulate gene expression as a consequence of micro/environmental exposures, working as environmental mediator

In her free time she enjoys crafts, running, hiking and movies.