Sara Sanders, PhD

Current Research

Sara is using genetic and cytological strategies to dissect the regulatory circuits coupling DNA replication to cell growth and nutrient availability.

Publications

Sanders, S., K. Joshi, P. A. Levin, and S. Iyer-Biwas (2022) Beyond the average: An updated framework for understanding the relationship between cell growth, DNA replication, and division in a bacterial system, PLoS Genetics, in press. bioRxiv2022.03.15.484524;doi:https://doi.org/10.1101/2022.03.15.484524

Sanders S, Bartee D, Harrison MJ, Phillips PD, Koppisch AT, Freel Meyers CL., 2018 “Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors.” PLoS One. 2018 May 17;13(5):e0197638.  PMCID: PMC5957436

Sanders, S., Vierling, RJ., Bartee, D., DeColli, AA., Harrison, MJ., Aklinski, JL., Koppisch, AT. and Freel Meyers, CL., 2017, “Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase,” ACS Infect Dis. PMCID: PMC5650741 

Colis, L., Peltonen, K., Sirajuddin, P., Liu, H., Sanders, S., Ernst, G., Barrow, JC. and Laiho, M., 2014, “DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response,” Oncotarget, 5(12):4361-4369. PMCID: PMC4147329

Colis, L., Ernst, G., Sanders, S., Liu, H., Sirajuddin, P., Peltonen, K., DePasquale, M., Barrow, JC. and Laiho, M., 2014, “Design, synthesis, and structure-activity relationships of pyridoquinazolinecarboxamides as RNA polymerase I inhibitors,” J Med Chem 57(11):4950-61.​ PMCID: PMC4059246​