Adam Eggebrecht, PhD

Assistant Professor

Radiology

Optical Radiology Lab at Mallinckrodt Institute of Radiology

Keywords:

Neurophotonics, Finite Element Modeling, NeuroDOT, autism spectrum disorder, Parkinson’s disease, language processing, brain plasticity

Research:

The Neurophotonics Lab of the Optical Radiology Labs is a diverse and interdisciplinary team whose research focuses on developing novel tools that extend mapping of brain function beyond current limitations. We harness the power of diffuse optics to create portable and wearable systems for unconstrained imaging of brain function including in subjects with implanted devices who are not able to be studied with MRI due to safety concerns. Our efforts are focused on three broad areas: hardware development, software and algorithm development, and applications from basic science to clinical care. Hardware development projects concentrate on optimizing signal-to-noise, image quality, subject comfort, and portability. Software and algorithm projects include Finite Element Modeling of light propagation, image reconstruction speed and accuracy, spatial registration of multiple data types, and development of a self-contained toolbox, NeuroDOT, for acquisition and analysis of diffuse optical tomography data. To further understanding of brain function in health and disease, our lab is focused on basic science and clinical applications including autism spectrum disorder, Parkinson’s disease, bedside imaging in the Intensive Care Unit, language processing, and brain plasticity from childhood development throughout the lifespan.

website