Stereotaxic brain injection
This procedure allows researchers to accurately target deep structures within the brain with drugs, genes or cells.
Includes:
- Equipment set up.
- Sterilization / disinfection of surgical tools and equipment.
- Disposal of biohazardous materials.
- Clean up in accordance with NIH guidelines.
- Initial preparation of DCM post surgical cards.
Does not include:
- Completion of DCM post surgical cards.
- Trial animals for testing coordinates.
- Virus, Drug or cells to be delivered.
- DCM housing costs.
Cost: $118 for first injection, $59 each additional. Ask for a quote for multiple animals, up to 5 per day.
Post-Operative care
This procedure will cause the rodent to experience a moderate pain level. Your animal will be given buprenorphine SR, which will provide pain relief for 72 hours.
The following is the responsibility of the client and not included in procedure price.
For an additional fee, surgery core personnel will complete the following tasks and fill out the required DCM documentation (surgical record cards).
Post-Surgical Monitoring Card
Card Instructions
- Monitor for 12-24 hrs for signs of pain and distress such as shaking, lethargy, chewing of tail, arched back, lack of grooming, etc.
- Check surgical wounds for infection and that the cannula is clean.
- Mark the green card daily for 2 time points and note the date sutures are removed on the front of the card. The card must remain on the cage until the sutures are removed in 7-10 days.
- Keep the card for 2 years.
Hazardous Materials Card
Required if administering hazardous substances.
Card Instructions
Place the animal in a clean cage after it recovers from surgery.
DCM will not change the cage or directly handle any animals that have been exposed to hazardous materials while the red card is on the cage. The investigator is responsible for changing the cage until the card is removed 3 days after the last administration of the hazardous compound.
Once the red card is removed, change the cage and place soiled cage into an autoclave or biohazard bag. Ask your animal facility staff where they want the cage left for disinfection.