| Structure of an LGR dimer-an evolutionary predecessor of glycoprotein hormone receptors Z Gong, S Chen, Z Fu, B Kloss, C Wang, OB Clarke, QR Fan, …bioRxiv, 2024.12. 31.630923 | 2025 |
| Structure of the Flotillin complex in a native membrane environment Z Fu, R MacKinnon Proceedings of the National Academy of Sciences 121 (29), e2409334121 | 2024 |
| An electrostatic cluster guides Aβ40 fibril formation in sporadic and Dutch-type cerebral amyloid angiopathy Z Fu, EJ Crooks, BA Irizarry, X Zhu, S Chowdhury, WE Van Nostrand, …Journal of structural biology 216 (2), 108092 | 2024 |
| Cryo-EM studies of the four E. coli paralogs establish ABCF proteins as master plumbers of the peptidyl-transferase center of the ribosome S Singh, RC Gentry, Z Fu, NA Bailey, CG Altomare, KH Wong, MJ Neky, …bioRxiv, 2023.06. 15.543498 | 2023 |
| Uncovering translation roadblocks during the development of a synthetic tRNA A Prabhakar, N Krahn, J Zhang, O Vargas-Rodriguez, M Krupkin, Z Fu, …Nucleic Acids Research 50 (18), 10201-10211 | 2022 |
| Mechanism of dual pharmacological correction and potentiation of human CFTR C Wang, Z Yang, BJ Loughlin, H Xu, G Veit, S Vorobiev, OB Clarke, …bioRxiv, 2022.10. 10.510913 | 2022 |
| Quantitative prediction and measurement of Piezo’s membrane footprint CA Haselwandter, YR Guo, Z Fu, R MacKinnonProceedings of the National Academy of Sciences 119 (40), e2208027119 | 2022 |
| Elastic properties and shape of the Piezo dome underlying its mechanosensory function CA Haselwandter, YR Guo, Z Fu, R MacKinnon Proceedings of the National Academy of Sciences 119 (40), e2208034119 | 2022 |
| Symmetric activation and modulation of the human calcium-sensing receptor J Park, H Zuo, A Frangaj, Z Fu (Co-first author), LY Yen, Z Zhang, L Mosyak, …Proceedings of the National Academy of Sciences 118 (51), e2115849118 | 2021 |
| High-resolution view of HIV-1 reverse transcriptase initiation complexes and inhibition by NNRTI drugs B Ha, KP Larsen, J Zhang, Z Fu, E Montabana, LN Jackson, DH Chen, …Nature Communications 12 (1), 2500 | 2021 |
| Anti-parallel β-hairpin structure in soluble Aβ oligomers of Aβ40-dutch and Aβ40-iowa Z Fu, WE Van Nostrand, SO Smith International Journal of Molecular Sciences 22 (3), 1225 | 2021 |
| Structure of human GABAB receptor in an inactive state J Park, Z Fu (Co-first author), A Frangaj, J Liu, L Mosyak, T Shen, VN Slavkovich, KM Ray, …Nature 584 (7820), 304-309 | 2020 |
| Structure of human GABA (B) receptor in an inactive state (Jun, 10.1038/s41586-020-2452-0, 2020) J Park, Z Fu (Co-first author), A Frangaj, J Liu, L Mosyak, T Shen, VN Slavkovich, KM Ray, …NATURE 583 (7818), E20-E20 | 2020 |
| Mechanism of ligand activation of a eukaryotic cyclic nucleotide− gated channel X Zheng, Z Fu (Co-first author), D Su, Y Zhang, M Li, Y Pan, H Li, S Li, RA Grassucci, …Nature structural & molecular biology 27 (7), 625-634 | 2020 |
| Structural and functional characterization of the bestrophin-2 anion channel AP Owji, Q Zhao, C Ji, A Kittredge, A Hopiavuori, Z Fu, N Ward, OB Clarke, …Nature structural & molecular biology 27 (4), 382-391 | 2020 |
| THERMODYNAMIC ENGINEERING ENABLES DETERMINATION OF NEAR-ATOMIC RESOLUTION CRYO-EM STRUCTURES OF HUMAN F508DEL-CFTR IN DIVERSE CONFORMATIONAL STATES SM Vorobiev, C Wang, Z Yang, OB Clarke, F Jiang, A Aleksandrov, Z Fu, …PEDIATRIC PULMONOLOGY 54, S81-S82 | 2019 |
| Late steps in bacterial translation initiation visualized using time-resolved cryo-EM S Kaledhonkar, Z Fu (Co-first author), K Caban, W Li, B Chen, M Sun, RL Gonzalez Jr, …Nature 570 (7761), 400-404 | 2019 |
| Single-Particle Cryo-Electron Microscopy Z Fu, S Kaledhonkar, B Shah, J FrankAcademic Press | 2019 |
| The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy Z Fu, G Indrisiunaite, S Kaledhonkar, B Shah, M Sun, B Chen, …Nature Communications 10 | 2019 |
| Time-resolved Cryo-EM Studies on Translation and Cryo-EM Studies on Membrane Proteins Z Fu Columbia University | 2019 |
| Structure and activity of lipid bilayer within a membrane-protein transporter W Qiu, Z Fu (Co-first author), GG Xu, RA Grassucci, Y Zhang, J Frank, WA Hendrickson, …Proceedings of the National Academy of Sciences 115 (51), 12985-12990 | 2018 |
| Real-time structural dynamics of late steps in bacterial translation initiation visualized using time-resolved cryogenic electron microscopy S Kaledhonkar, Z Fu (Co-first author), K Caban, W Li, B Chen, M Sun, RL Gonzalez Jr, …bioRxiv, 390674 | 2018 |
| Lipid Bilayer Structure in Native Cell Membrane Nanoparticles of Multidrug Exporter ACRB W Qiu, Z Fu (Co-first author), G Xu, RA Grassucci, WA Hendrickson, Y Zhang, J Frank, …Biophysical Journal 114 (3), 369a-370a | 2018 |
| The Structural Basis for Initiation Factor 2 Activation during Translation Initiation K Caban, M Pavlov, S Kaledhonkar, Z Fu, J Frank, M Ehrenberg, …Biophysical Journal 114 (3), 593a | 2018 |
| Time-resolved cryo-electron microscopy using a microfluidic chip S Kaledhonkar, Z Fu, H White, J FrankProtein Complex Assembly: Methods and Protocols, 59-71 | 2018 |
| A fast and effective microfluidic spraying-plunging method for high-resolution single-particle cryo-EM X Feng, Z Fu (Co-first author), S Kaledhonkar, Y Jia, B Shah, A Jin, Z Liu, M Sun, B Chen, …Structure 25 (4), 663-670. e3 | 2017 |
| Key intermediates in ribosome recycling visualized by time-resolved cryoelectron microscopy Z Fu, S Kaledhonkar, A Borg, M Sun, B Chen, RA Grassucci, M Ehrenberg, …Structure 24 (12), 2092-2101 | 2016 |
| Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure F Xu, Z Fu, S Dass, AME Kotarba, J Davis, SO Smith, WE Van NostrandNature communications 7 (1), 13527 | 2016 |
| O5‐06‐03: Cerebral Vascular Amyloid Seeds Drive Amyloid Ss‐Protein Fibril Assembly with a Distinct Anti‐Parallel Structure WE Van Nostrand, F Xu, Z Fu, M Hoos, S Dass, AM Kotarba, J Davis, …Alzheimer’s & Dementia 12, P391-P391 | 2016 |
| Mechanism of nucleated conformational conversion of Aβ42 Z Fu, D Aucoin, J Davis, WE Van Nostrand, SO SmithBiochemistry 54 (27), 4197-4207 | 2015 |
| Conformational changes induced by the A21G Flemish mutation in the amyloid precursor protein lead to increased A beta secretion in Alzheimer’s disease T Tang, Y Hu, P Kienlen-Campard, L El Haylani, M Decock, J Van Hees, …ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249 | 2015 |
| Capping of Aβ42 oligomers by small molecule inhibitors Z Fu, D Aucoin, M Ahmed, M Ziliox, WE Van Nostrand, SO SmithBiochemistry 53 (50), 7893-7903 | 2014 |
| Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice F Xu, AME Kotarba, MH Ou-Yang, Z Fu, J Davis, SO Smith, …Journal of Biological Chemistry 289 (25), 17895-17908 | 2014 |
| Conformational changes induced by the A21G Flemish mutation in the amyloid precursor protein lead to increased Aβ production TC Tang, Y Hu, P Kienlen-Campard, L El Haylani, M Decock, J Van Hees, …Structure 22 (3), 387-396 | 2014 |
| Combination of supercritical fluid extraction with counter‐current chromatography to isolate anthocyanidins from the petals of Chaenomeles sinensis based on … S Li, L Guo, C Liu, Z Fu, Y ZhangJournal of separation science 36 (21-22), 3517-3526 | 2013 |
| Pressurized liquid extraction coupled with countercurrent chromatography for systematic isolation of chemical constituents by preprogrammed automatic control Y Zhang, L Guo, C Liu, L Cong, Y Qi, D Li, S Li, J WangJournal of Chromatography B 935, 16-25 | 2013 |
| An unusual two-fold interpenetrating polyrotaxane motif comprised of two interlocked sets of identical diamond nets H Guo, Z Fu, X Guo, X Li, R Chen, Y Qi, H ZouJournal of Molecular Structure 1038, 8-11 | 2013 |