Seeking to avoid ‘full lockdown,’ cells monitor ribosome collisions: Cells activate individual quality control responses if they can (Links to an external site)

""

New research from Washington University in St. Louis shows that cells monitor for ribosome collisions to determine the severity of the problem and how best to respond when things start to go awry.

The research from the laboratory of Hani Zaher, associate professor of biology in Arts & Sciences, was published in the journal Molecular Cell.

Zaher Lab receives NIH grant

Hani Zaher, associate professor of biology in Arts & Sciences, received a $136,000 grant from the National Institutes of Health (NIH) to investigate the role of the ribosome in determining the fate of damaged mRNA.

Erica elected president of BALSA

Congratulations to Erica on being elected as president of the Biotechnology and Life Science Advising (BALSA) Group. 

Carrie and Leo’s paper published

Carrie and Leo‘s paper on ribosome traffic jam and quality control is published in Molecular Cell. Read the paper here

Bose, biology group net grant to work with high schoolers on STEM

Bose, along with two fellow assistant professors of biology, Joshua Blodgett and Hani Zaher, formed a high school partnership with the Gateway Science Academy, allowing local high school students to experience research in a university laboratory over the summer. Read full article here

Zaher Lab receives grant from Siteman Cancer Center

Hani Zaher, assistant professor of biology in Arts & Sciences, received a $400,000 award from the Siteman Cancer Center for a project titled “RNA as a Target of Alkylation Chemotherapy in Cancer.”

Will’s paper published in Cell Reports

Congratulations to Will. His paper on peptide release and methylation of release factor is published in Cell Reports. Read the paper here!

Erica receives a 3-year fellowship

Erica receives a 3-year fellowship from the Monsanto Excellence Fund for Graduate Fellowships in the Life Sciences.

Zaher Lab receives NIH grant

Hani Zaher, PhD, assistant professor of biology in Arts & Sciences, has received $268,008 of what’s expected to be a a five-year, $1.47 million grant from the National Institutes of Health for “The Role of Ribosome in Determining the Fate of Damaged MRNA.”

Zaher Lab receives NIH grant

Hani Zaher, PhD, assistant professor of biology in Arts & Sciences, has received $268,008 of what’s expected to be a a five-year, $1.47 million grant from the National Institutes of Health for “The Role of Ribosome in Determining the Fate of Damaged MRNA.”

Pierson wins Spector Prize

Each year, the Department of Biology in Arts & Sciences at Washington University in St. Louis awards a prize to a graduating senior in memory of Marion Smith Spector, a 1938 graduate who studied zoology under the late Viktor Hamburger, PhD. This year, Will Pierson has won the prize. The Spector Prize, first awarded in […]

It’s not always the DNA

""

Damaged messenger RNA can jam cellular machines that make protein. The failure to clear the jams and chew up bad messengers is associated with neurodegenerative diseases such as Alzheimer’s. Read the full article by Diana Lutz here.

Zaher Lab has moved!

The Zaher lab moves to its newly renovated space on the 5th floor of Monsanto Building.