2024
- He, X.Y., Gao, Y., Ng, D., Michalopoulou, E., George, S., Adrover, J., Sun, L., Albrengues, J., Daßler-Plenker, J., Han, X., Wan, L., Wu, X.S., Shui, L.S., Huang Y.H., Liu, B., Su, C., Spector, D.L., Vakoc, C.R., Van Aelst, L., Egeblad, M. (2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell, 42, 474–486. PMID: 38402610.
- This article was highlighted by Dr. Jing Hu in Cancer Cell: PMID: 38471456
- This article was highlighted by Dr. Seth Coffelt in Immunity: PMID:38599176
- Maia-Silva, D., Cunniff, P.J., Schier, A.C., Skopelitis, D., Trousdell, M.C., Moresco, P., Gao, Y., Kechejian, V., He, X.Y., Sahin, Y., Wan, L., Alpsoy, A., Liverpool, J., Krainer, A.R., Egeblad, M., Spector, D.L., Fearon, D.T., dos Santos, C.O., Taatjes, D.J., Vakoc, C.R. (2024). Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature Genetics. 2024 Jul;56(7):1377-1385. PMID: 38886586.
- Henry, S., Lewis, S.M., Cyrill, S.L., Callaway, M.K., Chatterjee, D., Somasundara, A., Jones, G., He, X.Y., Caligiuri, G., Ciccone, M.F., Diaz, I.A., Biswas, A., Hernandez E., Ha, T., Wilkinson, J.E., Egeblad, M., Tuveson, D.A., dos Santos, C.O. (2024). Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1. Nature Communications. 2024 Apr 16;15(1):3282. PMID: 38627380.
2023
- He, X.Y., Ng, D., Gao, Y., Michalopoulou, E., George, S., Adrover, J., Sun, L., Albrengues, J., Wan, L., Han, X., Vakoc, C.R., Van Aelst, L., Egeblad, M. (2023). Untangling the connection between stress and metastatic breast cancer. Cancer Res (2023) 83 (7_Supplement): 62. (AACR annunal meeting 2023, abstract).
- Adrover, J.M., McDowell, S.A.C., He, X.Y., Quail, D.F., Egeblad, M. (2023). NETworking with cancer: the bidirectional interplay between cancer and neutrophil extracellular traps. Cancer Cell, 41(3):505-526. PMID: 36827980
- Gao, Y., He, X.Y., Wu, X.S., Huang, Y.H., Toneyan, S., Ipsaro, J.J., Ha, T., Koo, P.K., Egeblad, M., Joshua-Tor, L., Vakoc, C.R. (2023). ETV6 dependency in Ewing sarcoma through antagonism of EWS-FLI1- mediated enhancer activation. Nature Cell Biology. 25, 298–308 (2023). PMID: 36658219 (Cover Story).
- This article was highlighted by Prof. Elizabeth R Lawlor in Nat Cell Biol: PMID: 36658218
2022
- He, X. Y., Ng, D., and Egeblad, M. (2022). Caught in a web: emerging roles of neutrophil extracellular traps in cancer. Annual Review of Cancer Biology. 6: 223-243.
- Wu, X.S., He, X.Y., Ipsaro, J.J., Huang, Y.H., Preall, J.B., Ng, D., Shue, Y.T., Sage, J., Egeblad, M., Joshua-Tor, L., Vakoc, C.R. (2022). OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. 607, 169–175 (2022). PMID: 35576971.
- Song, D., Adrover, J.M., Felice, C., Christensen, L.N., He, X.Y., Wilkinson, J.E., Janowitz, T., Egeblad, M., and Tonks, N.K. (2022). PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI insight. 7(14):e158199. PMID: 35866483
2021
- Sun, L., Kees, T., Almeida, A.S., Liu, B., He, X.Y., Ng, D., Spector, D., McNeish, I.A., Gimotty, P., Adams, S., Egeblad, M. (2021). Activating a collaborative innate-adaptive immune response to control breast and ovarian cancer metastasis. Cancer Cell. 39, 1361 –1374. PMID: 34478639. (Cover Story).
- This article was highlighted by Prof. Lisa M. Coussens in Cancer Cell: PMID: 34637745
- Barth, N D., Mendive-Tapia, L., Subiros-Funosas, R., Ghashghaei, O., Lavilla, R., Maiorino, L., He, X.Y., Dransfield, I., Egeblad, M., Vendrell, M. (2021) A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-induced Cancer Cell Death. Angewandte Chemie Intl Edit. 2021 Nov 11. PMID: 34762762
2020
- Fein, M.R.*, He, X.Y.*, Almeida, A.S., Bružas, E., Pommier, A., Yan, R., Eberhardt, A., Fearon, D.T., Van Aelst, L., Wilkinson, J.E., dos Santos, C.O., Egeblad, M. (2020). Cancer cell CCR2 orchestrates suppression of the adaptive immune response. The Journal of Experimental Medicine 217, (10). PMID: 32667673. *co-first author.
- He, X. Y., Ng, D., and Egeblad, M. (2020). Gut feelings block the flow: microbiota links stress to vascular disease. Immunity 53, 238-240. PMID: 32814021.
- Middleton, E.A., He, X.Y., Denorme, F., Campbell, R.A., Ng, D., Salvatore, S.P., et al. (2020). Neutrophil Extracellular Traps (NETs) Contribute to Immunothrombosis in COVID-19 acute respiratory distress syndrome. Blood. 136, 1169-1179. PMID: 32597954 (Cover Story).
- This article was highlighted by Prof. Andrés Hidalgo in Blood: PMID: 32882018
2019
- He, X. Y., Ng, D., Van Aelst, L., and Egeblad, M. (2019). Stressing Out about Cancer Immunotherapy. Cancer Cell 36, 468-470. PMID: 31715130
2018
- Huang, Y.H., Klingbeil, O., He, X.Y., Wu, X.S., Arun, G., Lu, B., et al. (2018). POU2F3 is a master regulator of a tuft cell like variant of small cell lung cancer. Genes and Development. 2018;32(13-14):915-28. PMID: 29945888 (Cover Story).
- This article was highlighted by Prof. Jane E. Johnson in Genes Dev: PMID: 29967289
Prior to 2018 (Selected Ph.D. works)
- He, X.Y., Xiang, C., Zhang, C.X., Xie, Y.Y., Chen, L., Zhang, G.X., Lu, Y., and Liu, G. (2015). p53 in the Myeloid Lineage Modulates an Inflammatory Microenvironment Limiting Initiation and Invasion of Intestinal Tumors. Cell Reports 13, 888-897. PMID: 26565902
- He, X.Y., Li, Y.J., Kalyanaraman, C., Qiu, L. L., Chen, C., Xiao, Q., Liu, W. X., Zhang, W., Yang, J. J., Chen, G., et al. (2016). GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors. Proceedings of the National Academy of Sciences of the United States of America 113, E5645-5654. PMID: 27601647.
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