The focus of the Willie Laboratory for Behavioral Neuromodulation is to characterize the function of brain circuits that control memory and arousal in normal and disease states. These studies leverage direct access to sampling and stimulating brain circuits in awake behaving neurosurgery patients and have direct implications for engineering novel neuromodulation strategies. His team is actively developing novel brain stimulation strategies to treat epilepsy, cognitive impairments, post-traumatic stress disorder (PTSD) and sleep disorders.