Select Publications
McCracken, S., Fitzpatrick, M.J., Hall, A.L., Wang, Z., Kerschensteiner, D., Morgan, J.L., and Williams, P.R. Diversity in homeostatic calcium set points predicts retinal ganglion cell survival following optic nerve injury in vivo (2023). Cell Reports 42, 113165.
Wang, Z., McCracken, S., and Williams, P.R. Transpupillary two-photon in vivo imaging of the mouse retina (2021). J Vis Exp 168, e61970.
Williams, P.R., Benowitz, L.I., Goldberg, J.L., and He, Z. Axon regeneration in the mammalian optic nerve (2020). Annu Rev Vis Sci 6, 195-213.
Zhang, Y.*, Williams, P.R.*#, Jacobi, A., Wang, C., Goel, A., Hirano, A.A., Brecha, N.C., Kerschensteiner, D., and He, Z. Elevating growth factor responsiveness and axon regeneratino by modulating presynaptic inputs (2019). Neuron 103(1), 39-51. *Equal contribution #Corresponding author
Witte, M.E., Schumacher, A.M., Mahler, C.F., Bewersdort, J.P., Lehmitz, J., Scheiter, A., Sanchez, P., Williams, P.R., Griesbeck, O., Naumann, R., Misgeld, T., and Kerschensteiner, M. Calcium influx through plasma-membrane nanoruptures drives axon degeneration in a model of multiple sclerosis (2019). Neuron 101(4), 615-624.
Liu, Y., Wang, X., Li, W., Zhang, Q., Li, Y., Zhang, Z., Zhu, J., Chen, B., Williams, P. R., Zhang, Y., Yu, B., and He Z. A sensitized IGF1 treatment restores corticospinal axon-dependent functions (2017). Neuron 95(4), 817-833.
Nawabi, H., Belin, S., Cartoni, R., Williams, P. R., Wang, C., Latremoliere, A., Wang, X., Fu, X., Taub, D.B., Yu, B., Woolf, C.J., Liu, J.S., Gabel, C.V., Steen, J.A. and He, Z. Doublecortin-like kinases promote neuronal survival and induce growth cone reformation via distinct mechanisms (2015). Neuron 88 (4), 1-16.
Williams, P. R., Marincu, B.N., Sorbara, C.D., Mahler, C.F., Schumacher, A.M., Griesbeck, O., Kerschensteiner, M. and Misgeld, T. A recoverable state of axon injury persists for hours after spinal cord contusion in vivo (2014). Nat Commun 5 (5683).
Kleele, T., Marinkovic, P., Williams, P. R., Stern, S., Weigand, E.E., Engerer, P., Naumann, R., Hartmann, J., Karl, R.M., Bradke, F., Bishop, D., Herms, J., Konnerth, A., Kershensteiner, M., Godinho, L. and Misgeld T. An assay to image neuronal microtubule dynamics in mice (2014). Nat Commun 5 (4827).
Breckwoldt, M.O., Pfister, F.M., Bradley, P.M., Marinkovic, P., Williams, P. R., Brill, M.S., Plomer, B., Schmalz, A., St. Clair, D.K., Naumann, R., Griesbeck, O., Schwarzlander, M., Godinho, L., Bareyre, F.M., Dick, T.P., Kerschensteiner, M. and Misgeld, T. Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo (2014). Nat Med 20 (5), 555-560.