• VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.

    Arhzaouy K, Papadopoulos C, Schulze N, Pittman SK, Meyer H, Weihl CC.

    Autophagy. 2019 Jan 18. doi: 10.1080/15548627.2019.1569933.

  • Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks.

    Meister-Broekema M, Freilich R, Jagadeesan C, Rauch JN, Bengoechea R, Motley WW, Kuiper EFE, Minoia M, Furtado GV, van Waarde MAWH, Bird SJ, Rebelo A, Zuchner S, Pytel P, Scherer SS, Morelli FF, Carra S, Weihl CC, Bergink S, Gestwicki JE, Kampinga HH.

    Nat Commun. 2018 Dec 17;9(1):5342. doi: 10.1038/s41467-018-07718-5.

  • 234th ENMC International Workshop: Chaperone dysfunction in muscle disease Naarden, The Netherlands, 8-10 December 2017.

    Weihl CC, Udd B, Hanna M; ENMC workshop study group.

    Neuromuscul Disord. 2018 Dec;28(12):1022-1030. doi: 10.1016/j.nmd.2018.09.004. Epub 2018 Sep 25.

  • Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.

    Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN.

  • Homozygous recessive MYH2 mutation mimicking dominant MYH2 associated myopathy.

    Findlay AR, Harms MB, Pestronk A, Weihl CC.

    Neuromuscul Disord. 2018 May 21. pii: S0960-8966(18)30002-6. doi: 10.1016/j.nmd.2018.05.006

  • CANOMAD and other chronic ataxic neuropathies with disialosyl antibodies (CANDA).

    Garcia-Santibanez R, Zaidman CM, Sommerville RB, Lopate G, Weihl CC, Pestronk A, Bucelli RC.

    J Neurol. 2018 Apr 9. doi: 10.1007/s00415-018-8853-4. [Epub ahead of print]

  • TIA1 variant drives myodegeneration in multisystem proteinopathy with SQSTM1 mutations.

    Lee Y, Jonson PH, Sarparanta J, Palmio J, Sarkar M, Vihola A, Evilä A, Suominen T, Penttilä S, Savarese M, Johari M, Minot MC, Hilton-Jones D, Maddison P, Chinnery P, Reimann J, Kornblum C, Kraya T, Zierz S, Sue C, Goebel H, Azfer A, Ralston SH, Hackman P, Bucelli RC, Taylor JP, Weihl CC, Udd B.

    J Clin Invest. 2018 Mar 1;128(3):1164-1177. doi: 10.1172/JCI97103. Epub 2018 Feb 19.

  • Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination.

    Lee Y, Chou TF, Pittman SK, Keith AL, Razani B, Weihl CC.

    Cell Rep. 2017 Aug 22;20(8):1994. doi: 10.1016/j.celrep.2017.08.019. No abstract available.

  • Regulation of SQSTM1/p62 via UBA domain ubiquitination and its role in disease.

    Lee Y, Weihl CC.

    Autophagy. 2017 Sep 2;13(9):1615-1616. doi: 10.1080/15548627.2017.1339845. Epub 2017 Aug 16.

  • Comparisons of ELISA and Western blot assays for detection of autophagy flux.

    Oh SH, Choi YB, Kim JH, Weihl CC, Ju JS.

    Data Brief. 2017 Jul 4;13:696-699. doi: 10.1016/j.dib.2017.06.045. eCollection 2017 Aug.

     

  • Cystinosis distal myopathy, novel clinical, pathological and genetic features.Cabrera-Serrano M, Junckerstorff RC, Alisheri A, Pestronk A, Laing NG, Weihl CC, Lamont PJ.Neuromuscul Disord. 2017 Sep;27(9):873-878. doi: 10.1016/j.nmd.2017.05.010. Epub 2017 May 15.
  • Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.Sergin I, Evans TD, Zhang X, Bhattacharya S, Stokes CJ, Song E, Ali S, Dehestani B, Holloway KB, Micevych PS, Javaheri A, Crowley JR, Ballabio A, Schilling JD, Epelman S, Weihl CC, Diwan A, Fan D, Zayed MA, Razani B.Nat Commun. 2017 Jun 7;8:15750. doi: 10.1038/ncomms15750.
  • Quantification of autophagy flux using LC3 ELISA.Oh SH, Choi YB, Kim JH, Weihl CC, Ju JS.Anal Biochem. 2017 Aug 1;530:57-67. doi: 10.1016/j.ab.2017.05.003. Epub 2017 May 4.
  • Establishing prevalence in rare neuromuscular diseases: A lesson from congenital myopathies.Bamaga AK, Weihl CC.Neurol Genet. 2017 Mar 21;3(2):e146. doi: 10.1212/NXG.0000000000000146. eCollection 2017 Apr. No abstract available.
  • Sporadic inclusion body myositis – a myodegenerative disease or an inflammatory myopathy.Weihl CC, Mammen AL.Neuropathol Appl Neurobiol. 2017 Feb;43(1):82-91. doi: 10.1111/nan.12384. Review.
  • Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis.Güttsches AK, Brady S, Krause K, Maerkens A, Uszkoreit J, Eisenacher M, Schreiner A, Galozzi S, Mertens-Rill J, Tegenthoff M, Holton JL, Harms MB, Lloyd TE, Vorgerd M, Weihl CC, Marcus K, Kley RA.Ann Neurol. 2017 Feb;81(2):227-239. doi: 10.1002/ana.24847. Epub 2017 Jan 27.
  • VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.Papadopoulos C, Kirchner P, Bug M, Grum D, Koerver L, Schulze N, Poehler R, Dressler A, Fengler S, Arhzaouy K, Lux V, Ehrmann M, Weihl CC, Meyer H.EMBO J. 2017 Jan 17;36(2):135-150. doi: 10.15252/embj.201695148. Epub 2016 Oct 17.
  • 215th ENMC International Workshop VCP-related multi-system proteinopathy (IBMPFD) 13-15 November 2015, Heemskerk, The Netherlands.Evangelista T, Weihl CC, Kimonis V, Lochmüller H; VCP related diseases Consortium.Neuromuscul Disord. 2016 Aug;26(8):535-47. doi: 10.1016/j.nmd.2016.05.017. Epub 2016 May 30. No abstract available.
  • TMEM184b Promotes Axon Degeneration and Neuromuscular Junction Maintenance.Bhattacharya MR, Geisler S, Pittman SK, Doan RA, Weihl CC, Milbrandt J, DiAntonio A.J Neurosci. 2016 Apr 27;36(17):4681-9. doi: 10.1523/JNEUROSCI.2893-15.2016.
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
  • Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.Bengoechea R, Pittman SK, Tuck EP, True HL, Weihl CC.Hum Mol Genet. 2015 Dec 1;24(23):6588-602. doi: 10.1093/hmg/ddv363. Epub 2015 Sep 11.
  • SQSTM1 splice site mutation in distal myopathy with rimmed vacuoles.Bucelli RC, Arhzaouy K, Pestronk A, Pittman SK, Rojas L, Sue CM, Evilä A, Hackman P, Udd B, Harms MB, Weihl CC.Neurology. 2015 Aug 25;85(8):665-74. doi: 10.1212/WNL.0000000000001864. Epub 2015 Jul 24.
  • In vivo kinetic approach reveals slow SOD1 turnover in the CNS.Crisp MJ, Mawuenyega KG, Patterson BW, Reddy NC, Chott R, Self WK, Weihl CC, Jockel-Balsarotti J, Varadhachary AS, Bucelli RC, Yarasheski KE, Bateman RJ, Miller TM.J Clin Invest. 2015 Jul 1;125(7):2772-80. doi: 10.1172/JCI80705. Epub 2015 Jun 15.
  • Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation.Jerath NU, Crockett CD, Moore SA, Shy ME, Weihl CC, Chou TF, Grider T, Gonzalez MA, Zuchner S, Swenson A.Case Rep Genet. 2015;2015:239167. doi: 10.1155/2015/239167. Epub 2015 Mar 23.
  • Altered cofactor regulation with disease-associated p97/VCP mutations.Zhang X, Gui L, Zhang X, Bulfer SL, Sanghez V, Wong DE, Lee Y, Lehmann L, Lee JS, Shih PY, Lin HJ, Iacovino M, Weihl CC, Arkin MR, Wang Y, Chou TF.Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1705-14. doi: 10.1073/pnas.1418820112. Epub 2015 Mar 16.
  • Targeted sequencing and identification of genetic variants in sporadic inclusion body myositis.Weihl CC, Baloh RH, Lee Y, Chou TF, Pittman SK, Lopate G, Allred P, Jockel-Balsarotti J, Pestronk A, Harms MB.Neuromuscul Disord. 2015 Apr;25(4):289-96. doi: 10.1016/j.nmd.2014.12.009. Epub 2015 Jan 6.
  • Autophagic vacuolar pathology in desminopathies.Weihl CC, Iyadurai S, Baloh RH, Pittman SK, Schmidt RE, Lopate G, Pestronk A, Harms MB.Neuromuscul Disord. 2015 Mar;25(3):199-206. doi: 10.1016/j.nmd.2014.12.002. Epub 2014 Dec 12.
  • The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis.Meyer H, Weihl CC.J Cell Sci. 2014 Sep 15;127(Pt 18):3877-83. doi: 10.1242/jcs.093831. Epub 2014 Aug 21. Review.
  • A novel mutation in VCP causes Charcot-Marie-Tooth Type 2 disease.Gonzalez MA, Feely SM, Speziani F, Strickland AV, Danzi M, Bacon C, Lee Y, Chou TF, Blanton SH, Weihl CC, Zuchner S, Shy ME.Brain. 2014 Nov;137(Pt 11):2897-902. doi: 10.1093/brain/awu224. Epub 2014 Aug 14.
  • Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.Stein KC, Bengoechea R, Harms MB, Weihl CC, True HL.J Biol Chem. 2014 Jul 25;289(30):21120-30.
  • Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains.Chou TF, Bulfer SL, Weihl CC, Li K, Lis LG, Walters MA, Schoenen FJ, Lin HJ, Deshaies RJ, Arkin MR.J Mol Biol. 2014 Jul 29;426(15):2886-99. doi: 10.1016/j.jmb.2014.05.022. Epub 2014 May 27.
  • Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis.Johnson JO, Pioro EP, Boehringer A, Chia R, Feit H, Renton AE, Pliner HA, Abramzon Y, Marangi G, Winborn BJ, Gibbs JR, Nalls MA, Morgan S, Shoai M, Hardy J, Pittman A, Orrell RW, Malaspina A, Sidle KC, Fratta P, Harms MB, Baloh RH, Pestronk A, Weihl CC, Rogaeva E, Zinman L, Drory VE, Borghero G, Mora G, Calvo A, Rothstein JD; ITALSGEN, Drepper C, Sendtner M, Singleton AB, Taylor JP, Cookson MR, Restagno G, Sabatelli M, Bowser R, Chiò A, Traynor BJ.Nat Neurosci. 2014 May;17(5):664-666. doi: 10.1038/nn.3688. Epub 2014 Mar 30.
  • Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function.Bibee KP, Cheng YJ, Ching JK, Marsh JN, Li AJ, Keeling RM, Connolly AM, Golumbek PT, Myerson JW, Hu G, Chen J, Shannon WD, Lanza GM, Weihl CC, Wickline SA.FASEB J. 2014 May;28(5):2047-61. doi: 10.1096/fj.13-237388. Epub 2014 Feb 5.
  • Increased autophagy accelerates colchicine-induced muscle toxicity.Ching JK, Ju JS, Pittman SK, Margeta M, Weihl CC.Autophagy. 2013 Dec;9(12):2115-25.
  • Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones.Udan-Johns M, Bengoechea R, Bell S, Shao J, Diamond MI, True HL, Weihl CC, Baloh RH.Hum Mol Genet. 2014 Jan 1;23(1):157-70. doi: 10.1093/hmg/ddt408. Epub 2013 Aug 19.
  • p62 expression and autophagy in αB-crystallin R120G mutant knock-in mouse model of hereditary cataract.Wignes JA, Goldman JW, Weihl CC, Bartley MG, Andley UP.Exp Eye Res. 2013 Oct;115:263-73. doi: 10.1016/j.exer.2013.06.026. Epub 2013 Jul 18.
  • Motor neuron involvement in multisystem proteinopathy: implications for ALS.Benatar M, Wuu J, Fernandez C, Weihl CC, Katzen H, Steele J, Oskarsson B, Taylor JP.Neurology. 2013 May 14;80(20):1874-80. doi: 10.1212/WNL.0b013e3182929fc3. Epub 2013 May 1.
  • Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS.Kim HJ, Kim NC, Wang YD, Scarborough EA, Moore J, Diaz Z, MacLea KS, Freibaum B, Li S, Molliex A, Kanagaraj AP, Carter R, Boylan KB, Wojtas AM, Rademakers R, Pinkus JL, Greenberg SA, Trojanowski JQ, Traynor BJ, Smith BN, Topp S, Gkazi AS, Miller J, Shaw CE, Kottlors M, Kirschner J, Pestronk A, Li YR, Ford AF, Gitler AD, Benatar M, King OD, Kimonis VE, Ross ED, Weihl CC, Shorter J, Taylor JP.Nature. 2013 Mar 28;495(7442):467-73. doi: 10.1038/nature11922. Epub 2013 Mar 3.
  • Rapamycin-induced autophagy aggravates pathology and weakness in a mouse model of VCP-associated myopathy.Ching JK, Weihl CC.Autophagy. 2013 May;9(5):799-800. doi: 10.4161/auto.23958. Epub 2013 Feb 25.
  • Monitoring autophagy in the treatment of protein aggregate diseases: steps toward identifying autophagic biomarkers.Weihl CC.Neurotherapeutics. 2013 Jul;10(3):383-90. doi: 10.1007/s13311-013-0180-y. Review.
  • mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.Ching JK, Elizabeth SV, Ju JS, Lusk C, Pittman SK, Weihl CC.Hum Mol Genet. 2013 Mar 15;22(6):1167-79. doi: 10.1093/hmg/dds524. Epub 2012 Dec 18.
  • Guidelines for the use and interpretation of assays for monitoring autophagy.
  • Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis.Qiu J, Tsien C, Thapalaya S, Narayanan A, Weihl CC, Ching JK, Eghtesad B, Singh K, Fu X, Dubyak G, McDonald C, Almasan A, Hazen SL, Naga Prasad SV, Dasarathy S.Am J Physiol Endocrinol Metab. 2012 Oct 15;303(8):E983-93. doi: 10.1152/ajpendo.00183.2012. Epub 2012 Aug 14.
  • Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.Harms MB, Sommerville RB, Allred P, Bell S, Ma D, Cooper P, Lopate G, Pestronk A, Weihl CC, Baloh RH.Ann Neurol. 2012 Mar;71(3):407-16. doi: 10.1002/ana.22683. Epub 2012 Feb 14.
  • Another VCP interactor: NF is enough.Weihl CC.J Clin Invest. 2011 Dec;121(12):4627-30. doi: 10.1172/JCI61126. Epub 2011 Nov 21.
  • An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors.Fuentealba RA, Marasa J, Diamond MI, Piwnica-Worms D, Weihl CC.Hum Mol Genet. 2012 Feb 1;21(3):664-80. doi: 10.1093/hmg/ddr500. Epub 2011 Nov 3.
  • Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations.Ritz D, Vuk M, Kirchner P, Bug M, Schütz S, Hayer A, Bremer S, Lusk C, Baloh RH, Lee H, Glatter T, Gstaiger M, Aebersold R, Weihl CC, Meyer H.Nat Cell Biol. 2011 Aug 7;13(9):1116-23. doi: 10.1038/ncb2301.
  • A knock-in mouse model for the R120G mutation of αB-crystallin recapitulates human hereditary myopathy and cataracts.Andley UP, Hamilton PD, Ravi N, Weihl CC.PLoS One. 2011 Mar 18;6(3):e17671. doi: 10.1371/journal.pone.0017671.
  • Valosin containing protein associated fronto-temporal lobar degeneration: clinical presentation, pathologic features and pathogenesis.Weihl CC.Curr Alzheimer Res. 2011 May;8(3):252-60. Review.
  • Novel GNE mutations in two phenotypically distinct HIBM2 patients.Weihl CC, Miller SE, Zaidman CM, Pestronk A, Baloh RH, Al-Lozi M.Neuromuscul Disord. 2011 Feb;21(2):102-5. doi: 10.1016/j.nmd.2010.11.002. Epub 2010 Dec 4.
  • Mitochondrial pathology in immune and inflammatory myopathies.Varadhachary AS, Weihl CC, Pestronk A.Curr Opin Rheumatol. 2010 Nov;22(6):651-7. doi: 10.1097/BOR.0b013e32833f108a. Review.
  • Sporadic inclusion body myositis: possible pathogenesis inferred from biomarkers.Weihl CC, Pestronk A.Curr Opin Neurol. 2010 Oct;23(5):482-8. doi: 10.1097/WCO.0b013e32833d3897. Review.
  • Quantitation of “autophagic flux” in mature skeletal muscle.Ju JS, Varadhachary AS, Miller SE, Weihl CC.Autophagy. 2010 Oct;6(7):929-35. doi: 10.4161/auto.6.7.12785. Epub 2010 Oct 24.
  • Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.Fuentealba RA, Udan M, Bell S, Wegorzewska I, Shao J, Diamond MI, Weihl CC, Baloh RH.J Biol Chem. 2010 Aug 20;285(34):26304-14. doi: 10.1074/jbc.M110.125039. Epub 2010 Jun 16.
  • Inclusion body myopathy, Paget’s disease of the bone and fronto-temporal dementia: a disorder of autophagy.Ju JS, Weihl CC.Hum Mol Genet. 2010 Apr 15;19(R1):R38-45. doi: 10.1093/hmg/ddq157. Epub 2010 Apr 21. Review.
  • p97/VCP at the intersection of the autophagy and the ubiquitin proteasome system.Ju JS, Weihl CC.Autophagy. 2010 Feb;6(2):283-5. Epub 2010 Mar 1. No abstract available.
  • Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1.Gurnett CA, Desruisseau DM, McCall K, Choi R, Meyer ZI, Talerico M, Miller SE, Ju JS, Pestronk A, Connolly AM, Druley TE, Weihl CC, Dobbs MB.Hum Mol Genet. 2010 Apr 1;19(7):1165-73. doi: 10.1093/hmg/ddp587. Epub 2010 Jan 2.
  • Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease.Ju JS, Fuentealba RA, Miller SE, Jackson E, Piwnica-Worms D, Baloh RH, Weihl CC.J Cell Biol. 2009 Dec 14;187(6):875-88. doi: 10.1083/jcb.200908115.
  • Acute and bilateral blindness due to optic neuropathy associated with copper deficiency.Naismith RT, Shepherd JB, Weihl CC, Tutlam NT, Cross AH.Arch Neurol. 2009 Aug;66(8):1025-7. doi: 10.1001/archneurol.2009.70.
  • Valosin-containing protein disease: inclusion body myopathy with Paget’s disease of the bone and fronto-temporal dementia.Weihl CC, Pestronk A, Kimonis VE.Neuromuscul Disord. 2009 May;19(5):308-15. doi: 10.1016/j.nmd.2009.01.009. Epub 2009 Apr 19. Review.
  • Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.Ju JS, Miller SE, Jackson E, Cadwell K, Piwnica-Worms D, Weihl CC.Autophagy. 2009 May;5(4):511-9. Epub 2009 May 6. Erratum in: Autophagy. 2010 Jul;6(5):676.
  • Inflammatory myopathies with mitochondrial pathology and protein aggregates.Temiz P, Weihl CC, Pestronk A.J Neurol Sci. 2009 Mar 15;278(1-2):25-9. doi: 10.1016/j.jns.2008.11.010. Epub 2008 Dec 20.
  • TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia.Weihl CC, Temiz P, Miller SE, Watts G, Smith C, Forman M, Hanson PI, Kimonis V, Pestronk A.J Neurol Neurosurg Psychiatry. 2008 Oct;79(10):1186-9. doi: 10.1136/jnnp.2007.131334.
  • Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease.Ju JS, Miller SE, Hanson PI, Weihl CC.J Biol Chem. 2008 Oct 31;283(44):30289-99. doi: 10.1074/jbc.M805517200. Epub 2008 Aug 20.
  • Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia.Watts GD, Thomasova D, Ramdeen SK, Fulchiero EC, Mehta SG, Drachman DA, Weihl CC, Jamrozik Z, Kwiecinski H, Kaminska A, Kimonis VE.Clin Genet. 2007 Nov;72(5):420-6.
  • Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice.Weihl CC, Miller SE, Hanson PI, Pestronk A.Hum Mol Genet. 2007 Apr 15;16(8):919-28. Epub 2007 Feb 28.
  • Motor neuron disease associated with copper deficiency.Weihl CC, Lopate G.Muscle Nerve. 2006 Dec;34(6):789-93.
  • Valproate may improve strength and function in patients with type III/IV spinal muscle atrophy.Weihl CC, Connolly AM, Pestronk A.Neurology. 2006 Aug 8;67(3):500-1. Epub 2006 Jun 14.
  • Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.Weihl CC, Dalal S, Pestronk A, Hanson PI.Hum Mol Genet. 2006 Jan 15;15(2):189-99. Epub 2005 Dec 1.
  • Adenoviral gene transfer of nitric oxide synthase increases cerebral blood flow in rats.Lüders JC, Weihl CC, Lin G, Ghadge G, Stoodley M, Roos RP, Macdonald RL.Neurosurgery. 2000 Nov;47(5):1206-14; discussion 1214-5.
  • Effect of adenovirus-mediated nitric oxide synthase gene transfer on vasospasm after experimental subarachnoid hemorrhage.Stoodley M, Weihl CC, Zhang ZD, Lin G, Johns LM, Kowalczuk A, Ghadge G, Roos RP, Macdonald RL.Neurosurgery. 2000 May;46(5):1193-202; discussion 1202-3.
  • The role of beta-catenin stability in mutant PS1-associated apoptosis.Weihl CC, Miller RJ, Roos RP.Neuroreport. 1999 Aug 20;10(12):2527-32.
  • Creutzfeldt-Jakob disease, new variant creutzfeldt-jakob disease, and bovine spongiform encephalopathy.Weihl CC, Roos RP.Neurol Clin. 1999 Nov;17(4):835-59. Review.
  • Alternative translation initiation of Theiler’s murine encephalomyelitis virus.Yamasaki K, Weihl CC, Roos RP.J Virol. 1999 Oct;73(10):8519-26.
  • Processing of wild-type and mutant familial Alzheimer’s disease-associated presenilin-1 in cultured neurons.Weihl CC, Ghadge GD, Miller RJ, Roos RP.J Neurochem. 1999 Jul;73(1):31-40.
  • Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.Weihl CC, Ghadge GD, Kennedy SG, Hay N, Miller RJ, Roos RP.J Neurosci. 1999 Jul 1;19(13):5360-9.