Why is embryo development so reproducible?
Control principles of multicellular patterns and forms
Embryo development is remarkably robust. Despite environmental fluctuations and the noisy nature of biochemical processes, tissue patterns and morphology are often highly stereotypic. Using zebrafish as our primary model, we seek to understand the reciprocal regulation between biochemical signaling and cell mechanics that enables robust control of tissue pattern, shape, and size during embryo development.