Integrative and Network-Specific Connectivity of the Basal Ganglia and Thalamus Defined in Individuals

Summary The basal ganglia, thalamus, and cerebral cortex form an interconnected network implicated in many neurological and psychiatric illnesses. A better understanding of cortico-subcortical circuits in individuals will aid in development of personalized treatments. Using precision functional mapping—individual-specific analysis of highly sampled human participants—we investigated individual-specific functional connectivity between subcortical structures and cortical functional networks. […]

Spatial and Temporal Organization of the Individual Human Cerebellum

This article was originally published by Scott Marek, Joshua S. Siegel, Evan M. Gordon, Ryan V. Raut, Caterina Gratton, Dillan J. Newbold, Mario Ortega, Timothy O. Laumann, Babatunde Adeyemo, Derek B. Miller, Annie Zheng, Katherine C. Lopez, Jeffrey J. Berg, Rebecca Coalson, Annie L. Nguyen, Donna Dierker, Andrew N. Van, Catherine R. Hoyt, Kathleen B. […]

Effect of sleep on overnight CSF amyloid-β kinetics

This article was originally published by Brendan Lucey, Terry Hicks, Jennifer McLeland, Cristina Toedebusch, Jill Boyd, Donald Elbert, Bruce Patterson, Jack Baty, John Morris, Vitaliy Ovod, Kwasi Mawuenyega, & Randall Bateman. Sleep disturbances are associated with future risk of Alzheimer disease. Disrupted sleep increases soluble amyloid β, suggesting a mechanism for sleep disturbances to increase […]