Need Statement:

There is a need to develop a system that will collect samples from infusion line effluent, in
preparation for concentration measurements that will validate UN&UP’s nanoparticle delivery
system for patients with ischemic stroke.

Project Scope:

There is a need for a device that collects periodic samples from a nanoparticle treatment in
preparation for concentration measurements. UN&UP must verify consistent concentrations
from their nanoparticle delivery system to optimize treatment for ischemic stroke patients. The device will collect equally timed samples into Eppendorf tubes without interfering with the magnetic properties of the nanoparticles. The system will ensure no loss of effluent between samples and the entire sampling process will be monitored. The final prototype (including hardware and software) along with CAD drawings of individual parts and assembly will be delivered to Mike Sabo on Friday, April 22, 2022.

Current method of sampling:

UN&UP’s current method of manual sampling is inefficient. The time is recorded on a stopwatch and the testing engineer physically pinches the IV line with his/her fingers between samples. To collect a full set of 66 samples for 60 seconds each, the engineer must collect samples for 66 minutes. Manual sampling is not efficient, not completely controlled, and poses a risk for contamination.