Zimmerman SM, Nay Lin P, Souroullas GP. Non-canonical functions of EZH2 in cancer. Frontiers Oncology. 2023. doi: 10.3389/fonc.2023.1233953
Zimmerman SM, Nixon SJ, Chen PY, Raj L, Smith SR, Paolini RL, Nay Lin P, Souroullas GP. Ezh2Y641F mutations co-operate with Stat3 to regulate MHC class I antigen processing and alter the tumor immune response in melanoma. Oncogene. 2022. doi:10.1038/s41388-022-02492-7
Goldsmith SR, Fiala MA, O’Neal J, Souroullas GP, Toama W, Vij R, Schroeder MA. EZH2 Overexpression in Multiple Myeloma: Prognostic Value, Correlation With Clinical Characteristics, and Possible Mechanisms. Clinical Lymphoma Myeloma and Leukemia, 2019
Liu JU, Souroullas GP, Diekman BO, Krishnamurthy K, Hall BM, Sorrentino JA, Parker JS, Sessions GA, Gudkov AV, Sharpless NE. Cells exhibiting strong p16INK4apromoter activation in vivo display features of senescence. PNAS. 2019
Souroullas GP, Fedoriw Y, Staudt LM, Sharpless NE. Lkb1 deletion in murine B lymphocytes promotes cell death and cancer. Experimental Hematology (2017), doi: 10.1016/j.exphem.2017.04.005
Souroullas GP, Jeck WR, Parker JS, Simon JM, Liu JY, Paulk J, Xiong J, Clark KS, Fedoriw Y, Qi J, Burd CE, Bradner JE, Sharpless NE. An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation. Nature Medicine. 2016. May 6; (22)6
Souroullas GP, Sharpless NE. Stem cells: Down’s syndrome link to ageing. Nature. 2013 Sep 19;501(7467):325-6
Burd CE, Liu W, Huynh MV, Waqas MA, Gillahan JE, Clark KS, Fu K, Martin BL, Jeck WR, Souroullas GP, Darr DB, Zedek DC, Miley MJ, Baguley BC, Campbell SL, Sharpless NE. Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma. Cancer Discovery. 2014 Dec;4(12):1418-29
Souroullas GP, Sharpless NE. mTOR signaling in melanoma: oncogene-induced pseudo-senescence? Cancer Cell. 2015 Jan 12;27(1):3-5
Souroullas GP, Salmon JM, Sablitzky F, Curtis DJ, Goodell MA. Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell. 2009 Feb 6;4(2):180-6.
Lukov GL, Rossi L, Souroullas GP, Mao R, Goodell MA. The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation. Leukemia Research. 2011 Mar;35(3):405-12.
Souroullas GP, Goodell MA. A new allele of Lyl1 confirms its important role in hematopoietic stem cell function. Genesis. 2011 Jun;49(6):441-8
Zohren F, Souroullas GP, Luo M, Gerdemann U, Imperato MR, et al. The transcription factor Lyl1 regulates lymphoid specification and the maintenance of early T lineage progenitors. Nature Immunology. 2012 Jul 8;13(8):761-9.
Kahle JJ*, Souroullas GP*, Yu P, Zohren F, Lee Y, et al. Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery. PLoS Genetics. 2013 Mar;9(3):e1003359. *co-first authors
Diamond TL, Souroullas G, Weiss KK, Lee KY, Bambara RA, et al. Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque. Journal of Biological Chemistry. 2003 Aug 8;278(32):29913-24.