November 6th, 2019 – More than a year ago, in collaboration with Tanner Johanns and Charles Kaufman, also of WashU, we put together an LOI for a Phase I clinical trial through the NIH/CTEP program.  The proposal is based on our preclinical data on the interaction between EZH2 and BRAF in melanoma.  The LOI has been approved and the drug company has committed to provide the drug for the trial!  One of our goals as a cancer research lab is to carry out robust and thorough  basic science and always try to translate and apply those findings to the clinic… this gives us tremendous motivation to keep going!

November 5th, 2019 – Gejae Jeffers, graduate student in DBBS Molecular Genetics and Genomics Program, joins the lab for a rotation.  Welcome Gejae!

October 14th, 2019 – Rachel Paolini, graduate student in DBBS Molecular Genetics and Genomics Program, joins the lab for a rotation.  Welcome Rachel!

September 23rd, 2019 – Look at that, our first FACS analysis! We knocked down some genes, grew some cells, injected them into mice, harvested tumors and analyzed the tumor immune response… looks like we are doing some real science!

September 3rd, 2019 – Leela decides to extend her summer research and keep working in our lab for the rest of the academic year.  We are glad to have her back!

June 24th, 2019 – Jessica Harrison, graduate student in DBBS Human and Statistical Genetics Program, joins the lab for a summer rotation.  Welcome Jessica!

May 20th, 2019 – Leela Raj, a WashU undergraduate, joins the lab for the summer.  Welcome Leela!

May 1st, 2019 – OMG, it’s been a year since we started!  Celebratory picture by the Ellen S. Clark Hope Plaza Fountain on the WashUMed campus! (we always forget to take pictures during lunch)

March 15, 2019 – Our lab is now officially a member of the Siteman Comprehensive Cancer Center and part of the Solid Tumor Therapeutics Program.  We are very excited to be part of this amazing scientific community and look forward to working with our colleagues and contribute towards the Center’s goals!  You can learn more about the different research programs at Siteman here.


February 12, 2019 – George’s last paper from his postdoc was recently published in PNAS.  Most of this work was done by “the best graduate student ever”, Jie-Yu Liu.  If you want to learn more about a new p16 reporter, check it out here.


January 10th, 2018 – DBBS-DB student Laura Fischer has joined the lab for a rotation.  Laura will be shearing chromatin, IP’ing methylated histones and figuring out some interesting chromatin dynamics in the EZH2 Y641F mutants!  Welcome Laura!

December 2018 –  Sarah Zimmerman joined our lab as a postdoctoral research associate.  Welcome Sarah!

November 2018 – George is very excited and grateful to the Cancer Research Foundation (CRF) for the Young Investigator Award!  Thank you for supporting our research!



October 30th, 2018 – DBBS-MCB student Kent Lin has joined the lab for a rotation.  He will be working on some cool epigenetic stuff!  Welcome Kent!



August 10th, 2018 – We are very excited to receive a Notice of Award for the Transition Career Development Award from the NCI!


July 11th, 2018 – We are in business!  We might not have a direct view of the Arch, but we have lots of space and we love it.

Our new assistants, Eppi and Nano, are already hard at work!

June 4th, 2018 – Samantha Nixon joins the lab as a Research Technician.  Sammi recently graduated from the University of Wisconsin Oshkosh.  She was brave enough to move to St. Louis, with her dog Kona, and be the lab’s first employee!  Welcome Sammi!

May 24th, 2018 – As promised, some fresh coat of paint… we are almost there…


May 1st, 2018 – Day 1.  Empty lab waiting for some TLC


May 1st, 2018 – George’s first day at work.  Lots to do and lots to learn, but taking a moment to take it all in. First things first, found the coffee machine!