Schedule

            Patient

• 8:20-8:40 Survival and Success: Which hearts and which patients are most favorable for VT ablation?

            Daniel Cooper, MD

• 8:40-9:00 Show me the data! Update on clinical trials

            Marye Gleva, MD

• 9:00-9:10 Wrap-up / Q&A

            Phillip Cuculich, MD with Speaker Panel

9:10-10:20    What Are They Doing in the Basement? A Primer on Radiotherapy

• 9:10-9:30 Physics of radiotherapy

           Nels Knutson, MD

• 9:30-9:50 Biology of radiotherapy

           Pamela Samson, MD, MPH

• 9:50-10:10 Cardiotoxicity of radiotherapy

           Shahed Badiyan, MD

• 10:10-10:20 Wrap-up / Q&A

           Cliff Robinson, MD with Speakers

10:20-10:40  COFFEE BREAK (Provided)

10:40-11:50  Preclinical Data Supporting Cardiac SBRT – Known knowns, known unknowns, and unknown unknowns.

• 10:40-11:00 Summary of Preclinical Data with Photons

           Oliver Blanck, PhD (UKSH, Kiel, Germany)

• 11:00-11:20 Update on Mayo Preclinical Work: Protons, Photons, and Carbon

           Amanda Deisher, PhD (Mayo Clinic, Rochester, MN)

• 11:20-11:30 SNUH Preclinical Work

           Ji Hyun Chang, MD, PhD (Seoul National University Hospital, Seoul, Korea)

• 11:30-11:40 WUSTL Preclinical Work:

           Stacey Rentschler, MD, PhD

• 11:40-11:50 Wrap-up / Q&A

           Stacey Rentschler, MD, PhD with Speakers

11:50-12:00   GROUP PHOTO

12:00-1:15      LUNCH (Provided) – Interview with a patient starting at 12:45.

1:15-1:45  KEYNOTE 1 – Clinical Trials for VT: Lessons Learned

           John Sapp, MD (Professor of Medicine, Physiology & Biophysics, Dalhousie University,
Halifax, Nova Scotia, Canada. Lead Investigator, VANISH and VANISH2 trials)

SESSION 2 – Mapping and Treating

1:45-2:35  How Do We Create a Target?

           Phillip Cuculich, MD

           Breakout Speaker – Timm Dickfield, MD, PhD (University of Maryland, Baltimore, MD)

           Breakout Speaker – Paul Zei, MD, PhD (Brigham and Womens, Boston, MA)      

2:35-3:25  How Do We Treat the Target?

           Cliff Robinson, MD

           Breakout Speaker – Geoff Hugo, PhD

           Breakout Speaker – Paul Keall, PhD (University of Sydney, Sydney, Australia)

3:25-3:40 Wrap-up / Q&A / Catch-up

           Phillip Cuculich, MD and Cliff Robinson, MD with speakers

3:40-4:00  COFFEE BREAK (Provided)

SESSION 3 – Clinical Outcomes

4:00-6:00  Clinical experiences to date

• 4:00-4:20 Overview of Global Treatments and Washington University in St. Louis (St. Louis, MO)

          Phillip Cuculich, MD

• 4:20-4:40 University Hospital Ostrava (Ostrava, Czech Republic)

          Jakub Cvek, PhD

• 4:40-4:50 University of Maryland (Baltimore, MD)

          Pranshu Mohindra, MD

• 4:50-5:10 Lausanne University Hospital (CHUV, Lausanne, Switzerland)

          Claudia Herrera-Siklody, MD

• 5:10-5:20 University Hospital Zurich (USZ, Zurich, Switzerland)

          Nicolaus Andratschke, MD

• 5:20-5:40 Brigham and Women’s Hospital (Boston, MA)

          Paul Zei, MD, PhD

• 5:40-6:00 Multi-centre Experience within the NHS (Sheffield, Newcastle, and Middlesbrough, UK)

          Matthew Hatton, MB ChB, MSc (Sheffield Teaching Hospital, Sheffield, UK)

           Ewen Shepherd, MB ChB (Newcastle Upon Tynes Hospitals, Newcastle Upon Tynes, UK)

          Jim Daniel, MSCi Hons, MsC (South Tees Hospital, Middlesbrough, UK)

6:00-6:20  QA / Panel Discussion

          Speakers

6:00-7:30  DRINKS/APPETIZERS (Provided) with Optional Tour of Siteman Cancer Center, Department of Radiation Oncology

7:30+  DINNER (On your own)

The Eric P. Newman Education Center is located in St. Louis’ Central West End neighborhood, and is close to a wide variety of excellent restaurants. We encourage attendees to take advantage of the free evening to explore one of the many nearby options!

Thursday, September 12

8:00  CHECK-IN & CONTINENTAL BREAKFAST

9:00  Welcome and Introduction

           Cliff Robinson, MD

SESSION 4 – Real Life Targeting and Treating

9:00-10:20  Group Team Hands-On Interactive Cases for Radiation Oncology and Electrophysiology!

• 9:00-10:00 Hand-On Interactive Cases

           All attendees

• 10:00-10:20 Wrap-up / Q&A

           Phillip Cuculich, MD and Cliff Robinson, MD     

10:20-10:40  COFFEE BREAK

10:40-11:10  KEYNOTE 2 – Introducing Novel Therapies into Clinical Practice: Lessons Learned from Lung SBRT

           Robert Timmerman, MD (Professor of Radiation Oncology and Neurological Surgery, UT Southwestern, Dallas, TX. Lead Investigator, RTOG 0236 and 0618 Trials)

11:10-11:30  FDA Regulatory Role (please e-mail Ouided.Rouabhi@fda.hhs.gov for copies)

          Ouided Raubhi, MS (Cardiac Ablation, Mapping, and Imaging Devices Team, Office of Cardiovascular Devices, U.S. Food and Drug Administration)

SESSION 5 – Working Lunch, Working Groups, and Working Towards Future Clinical Trials       

11:30-12:00  PICK UP LUNCH (Provided)

 12:00-12:30  Global Registry

           Phillip Cuculich, MD with all attendees (interactive)

  12:30-2:00 Consortiums, Trials

• UK-VT SABR Consortium

           Matthew Hatton, MB ChB, MSc (Sheffield Teaching Hospital, Sheffield, UK)

           Matthew Bates, MB ChB, PhD (South Tees Hospital, South Tees, UK)

• EU – STOPSTORM Consortium

           Joost Verhoeff, MD, PhD (UMC Utrecht, Utrecht, Netherlands)

• EU – Kiehl, Germany – RAVENTA Trial

           Oliver Blanck, PhD (UKSH, Kiel, Germany)

• EU – Czech Republic – STAR-VT Trial, etc.

           Radek Neuwirth, MD (Masaryk University, Brno, Czech Republic)

• US – St. Louis, MO – Center for Noninvasive Cardiac Radioablation (CNCR) / ENCORE-MULTI Trial

           Cliff Robinson, MD

           2:00-3:00 Working Groups

           Phillip Cuculich, MD and Cliff Robinson, MD with all attendees (interactive)           

 3:00 SAFE TRAVELS!