Employing state-of-the-art rational drug design tools, we are interested in the synthesis of small organic molecules, peptide conjugates, and metalloprobes to interrogate important biological pathways and identify new biomarkers. Other areas of near term interests are to extend the repertoire of our reporter probes into various biological applications via development of novel heterocyclic compounds for imaging reporter gene expression and cancer biology, chemiluminescent substrates for imaging inflammation, and near infrared optical probes for understanding critical disease-specific biochemical mechanism(s).

Print Friendly, PDF & Email