Risks

The study staff are trained to conduct this study. Our priority is your safety and well-being. However, you may experience one or more of the risks indicated below from being in this study. In addition to these, there may be other unknown risks, or risks that we did not anticipate, associated with being in this study. All normal precautions will be taken to minimize any risks.

Blood collection

Likely/common: Minor pain, bleeding, bruising or swelling may result from the IV placement procedure. Some people become dizzy or feel faint.

Less likely/less common: There is a less likely risk of feeling lightheaded, dizzy, or nauseous when you get out of bed after your blood collection. 

Rare: There is a very rare risk of infection or blood clot from placement of an IV catheter. There is a rare risk of fainting.

MRI and PET imaging

Likely: Lying still in the scanner may produce some stiffness. Study staff will be nearby to stop the study in case you become uncomfortable.

Less likely: You may experience aching in your joints and muscles from lying very still. This research may produce some anxiety and discomfort. If you experience these symptoms and do not wish to continue, the study will be stopped immediately. People with a fear of being in small, enclosed places may find this procedure uncomfortable.

Rare: A small fraction of participants experience claustrophobia (anxiety due to being restrained or in a confined area) while some experience dizziness or feel faint. If you experience these symptoms and do not wish to continue, the study will be stopped immediately.

Medical devices: There is a rare risk of malfunction of worn or implanted electronic medical devices such as a pacemaker, bone hardware, cardiac stent, or device placed in your uterus. If you have electronic medical devices, please make sure you tell your study doctors and research staff. The PET and MRI scans may cause a malfunction of electronic medical devices or damage to surrounding tissue.