Naoshad Muhammad, Fiona Ruiz, Jennifer Stanley, Ramachandran Rashmi, Kevin Cho, Kay Jayachandran, Michael C Zahner, Yi Huang, Jin Zhang, Stephanie Markovina, Gary J Patti, Julie K Schwarz Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy Cancer Res. 2022 Dec 16;82(24):4515-4527. doi: 10.1158/0008-5472.CAN-21-4369.
Varintra E Lander, Jad I Belle, Natalie L Kingston, John M Herndon, Graham D Hogg, Xiuting Liu, Liang-I Kang, Brett L Knolhoff, Savannah J Bogner, John M Baer, Chong Zuo, Nicholas C Borcherding, Daniel P Lander, Cedric Mpoy, Jalen Scott, Michael Zahner, Buck E Rogers, Julie K Schwarz, Hyun Kim, David G DeNardo Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade Cancer Discovery. 2022 Dec 2;12(12):2774-2799. doi: 10.1158/2159-8290.CD-22-0192.
Floberg, JM, Zhang J, Muhammad N, DeWees TA, Inkman M, Chen K, Lin AJ, Rashmi R, Jayachandran K, Edelson BT, Siegel BA, Dehdashti F, Grigsby PW, Markovina S, Schwarz JK. Standardized uptake value for 18F-fluorodeoxyglucose is a marker of inflammatory state and immune infiltrate in cervical cancer. Clin Cancer Res, 2021 Apr [in publication] doi: 10.1158/1078-0432. PMID: 33820781. PMCID: MPC8338789 (available on 2022-02-01). **article selected for journal highlight .
Ruiz FJ, Inkman M, Rashmi R, Muhammad N, Gabriel N, Miller CA, McLellan MD, Goldstein M, Markovina S, Grigsby PW, Schwarz JK. HPV transcript expression affects cervical cancer response to chemoradiation. JCI Insight. 2021 Aug 23;6(16):138734.doi: 10.1172/jci.insight138734. PMID: 34255749. PMCID: PMC8409981.
**article selected for journal highlight
Ruiz FJ, Sundaresan A, Zhang J, Pedamallu CS, Halle MK, Srinivasasainagendra V, Zhang J, Muhammad N, Stanley J, Markovina S, Tiwari HK, Grigsby PW, Krakstad C, Schwarz JK, Ojesina AI. Genomic Characterization and Therapeutic Targeting of HPV Undetected Cervical Carcinomas. Cancers (Basel). 2021 Sep 10;13(18):4551.doi: 10.3390/cancers13184551.PMID: 34572780. PMCID: PMC8467954.
Jin Zhang, Ramachandran Rashmi , Matthew Inkman , Kay Jayachandran , Fiona Ruiz , Michael R Waters , Perry W Grigsby , Stephanie Markovina, Julie K Schwarz
Integrating imaging and RNA-seq improves outcome prediction in cervical cancer
J Clin Invest 2021 Mar 1;131(5):e139232. doi: 10.1172/JCI139232. PMID: 33645544PMCID: PMC7919714 (available on 2021-06-01)DOI: 10.1172/JCI139232
Rashmi R, Jayachandran K, Zhang J, Menon V, Muhammad N, Zahner M, Ruiz F, Zhang S, Cho K, Wang Y, Huang X, Huang Y, McCormick ML, Rogers BE, Spitz DR, Patti GJ, Schwarz JK. Glutaminase inhibitors induce thiol-mediated oxidative stress and radio-sensitization in treatment resistant cervical cancers. Mol Cancer Ther. 2020 Oct 21:molcanther.0271.2020. doi: 10.1158/1535-7163.MCT-20-0271. Online ahead of print.PMID: 33087507
Hegde S, Krisnawan VE, Herzog BH, Zuo C, Breden MA, Knolhoff BL, Hogg GD, Tang JP, Baer JM, Mpoy C, Lee KB, Alexander KA, Rogers BE, Murphy KM, Hawkkins WG, Fields RC, DeSelm CJ, Schwarz JK, DeNardo DG. Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 2020 Mar 16;37(3):289-307.e9. doi: 10.1016/j.ccell.2020.02.08. PMID: 32183949.
Floberg JM, Wang L, Bandara N, Rashmi R, Mpoy C, Garbow JR, Rogers BE, Patti GJ, Schwarz JK Altering cellular reducing potential changes 64Cu-ATSM signal with or without hypoxia. J Nucl Med. 2019 Oct 4. pii: jnumed.119.230805. doi: 10.2967/jnumed.119.230805. [Epub ahead of print] PMID: 31586008
Amy J. Wisdom, Cierra S. Hong, Alexander J. Lin, Yu Xiang, Daniel E. Cooper, Jin Zhang, Eric S. Xu, Hsuan-Cheng Kuo, Yvonne M. Mowery, David J. Carpenter, Kushal T. Kadakia, Jonathon E. Himes, Lixia Luo, Yan Ma, Nerissa Williams, Diana M. Cardona, Malay Haldar, Yarui Diao, Stephanie Markovina, Julie K. Schwarz, and David G. Kirsch Neutrophils Promote Tumor Resistance to Radiation Therapy. PNAS first published August 28, 2019 https://doi.org/10.1073/pnas.1901562116
Panni RZ, Herndon JM, Zuo C, Hegde S, Hogg GD, Knolhoff BL, Breden MA, Li X, Krisnawan VE, Khan SQ, Schwarz JK, Rogers BE, Fields RC, Hawkins WG, Gupta V, DeNardo DG. Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies. Science Translational Medicine. July 3, 2019. DOI: 10.1126/scitranslmed.aau9240
Rashmi R, Huang X, Floberg JM, Elhammali A, McCormick ML, Patti GJ, Spitz DR, Schwarz JK*. Radio-resistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism. Cancer Res. 2018 Jan 16. [Epub ahead of print]
*Denotes corresponding or senior authorship.
**Article selected for journal highlight.