Featured Publications

Postdoctoral fellow Dr. Natalie Wee presents at ASBMR

Postdoctoral fellow Dr. Natalie Wee presents at ASBMR
Dr. Wee was selected for a podium presentation for her work entitled "Shared autonomic pathways connect bone marrow and peripheral adipose tissues across the central neuraxis". She presented during the session on 'Bone-Lipid Connections' at the recent 2019 ASBMR meeting. This work was also recently accepted for publication in Frontiers in Endocrinology. Congratulations Natalie!

Peripheral Neuropathy as a Component of Diabetic Skeletal Disease

Peripheral Neuropathy as a Component of Diabetic Skeletal Disease
The goal of this review is to explore clinical associations between peripheral neuropathy and diabetic bone disease and to discuss how nerve dysfunction may contribute to dysregulation of bone metabolism, reduced bone quality, and fracture risk. In addition, we address therapeutic and experimental considerations to guide patient care and future research evaluating the emerging relationship […]

Exploiting Self-Capacitances for Wireless Power Transfer.

Exploiting Self-Capacitances for Wireless Power Transfer.
Conventional approaches for wireless power transfer rely on the mutual coupling (near-field or far-field) between the transmitter and receiver transducers. In this paper, we show that when the operational power-budget requirements are in the order of microwatts, a self-capacitance (SC)-based power delivery has significant advantages in terms of the power transfer-efficiency, receiver form-factor, and system […]

Characterization of the bone marrow adipocyte niche with 3D-EM.

Characterization of the bone marrow adipocyte niche with 3D-EM.
The bone marrow adipocyte (BMA) exists in a microenvironment containing unique populations of hematopoietic and skeletal cells. To study this microenvironment at the sub-cellular level, we performed a three-dimensional analysis of the ultrastructure of the BMA niche with focused ion beam scanning electron microscopy (FIB-SEM).

2019

  • Beeve AT, Brazill JB, Scheller EL. (2019) Peripheral neuropathy as a component of skeletal disease in diabetes. Curr Osteoporos Rep. Aug 7. doi: 10.1007/s11914-019-00528-8
  • Brazill JB, Beeve AT, Craft CS, Ivanusic JJ, Scheller EL. (2019) Nerves in bone: evolving concepts in pain and anabolism. J Bone Miner Res. Jun 27. doi: 10.1002/jbmr.3822. 
  • McCabe IC, Fedorko A, Meyers MG Jr, Leinninger G, Scheller E, McCabe LR. Novel leptin receptor signaling mutants identify location and sex-dependent modulation of bone density, adiposity, and growth. (2019) J Cell Biochem. 120(3):4398-4408. PMCID: PMC6336499
  • Zou W, Rohatgi N, Brestoff JR, Zhang Y, Scheller EL, Craft CS, Brodt MD, Migotsky N, Silva MJ, Harris CA, Teitelbaum SL. (2019) Congenital lipodystrophy induces severe osteosclerosis. PLoS Genet. Jun 24;15(6):e1008244. PMCID: 31233501
  • Robles H, Park S, Joens MS, Fitzpatrick JAJ, Craft CS, Scheller EL. (2019) Characterization of the bone marrow adipocyte niche with three-dimensional electron microscopy. Bone. 118:89-98. PMCID: PMC6063802
  • Scheller EL, Khandaker S, Learman BS, Cawthorn WP, Anderson LM, Pham HA, Robles H, Wang Z, Li Z, Parlee SD, Simon BR, Mori H, Bree AJ, Craft CS, MacDougald OA. (2019) Bone marrow adipocytes resist lipolysis and remodeling in response to β-adrenergic stimulation. Bone. 118:32-41. PMCID: PMC6062480
  • Alazzawi Y, Aono K, Scheller EL, Chakrabartty S. Exploiting Self-Capacitances for Wireless Power Transfer. (2019) IEEE Trans Biomed Circuits Syst. 13(2):425-434.
  • Silva MJ, Eekhoff JD, Patel T, Kenney-Hunt JP, Brodt MD, Steger-May K, Scheller EL, Cheverud JM. Effects of High-Fat Diet and Body Mass on Bone Morphology and Mechanical Properties in 1100 Advanced Intercross Mice. (2019) J Bone Miner Res. doi: 10.1002/jbmr.3648.

2018

  • Turecamo SE, Walji TA, Broekelmann TJ, Williams JW, Ivanov S, Wee NK, Procknow JD, McManus MR, Randolph GJ, Scheller EL, Mecham RP, Craft CS. (2018) Contribution of metabolic disease to bone fragility in MAGP1-deficient mice. Matrix Biol. 67:1-14.
  • Bauerle KT, Hutson I, Scheller EL, Harris CA. (2018) Glucocorticoid Receptor Signaling Is Not Required for In Vivo Adipogenesis. Endocrinology. 159(5):2050-2061
  • Li Z, Hardij J, Bagchi DP, Scheller EL, MacDougald OA. (2018) Development, regulation, metabolism and function of bone marrow adipose tissues. Bone. 110:134-140.
  • Craft CS, Li Z, MacDougald OA, Scheller EL. (2018) Molecular differences between subtypes of bone marrow adipocytes. Current Molecular Biology Reports. (in press).
  • Craft CS, Broekelmann TJ, Mecham RP. (2018) Microfibril-associated glycoproteins MAGP-1 and MAGP-2 in disease. Matrix Biol. doi: 10.1016/j.matbio.2018.03.006. [Epub ahead of print] 
  • Stoka KV, Maedeker JA, Bennett L, Bhayani SA, Gardner WS, Procknow JD, Cocciolone AJ, Walji TA, Craft CS, Wagenseil JE. (2018) Effects of Increased Arterial Stiffness on Atherosclerotic Plaque Amounts. J Biomech Eng. 140(5)

2017

  • Craft CS, Wee NK, Scheller EL. (2017)  Adipocytes and Bone. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 8th Edition. (Accepted)
  • Scheller EL, Hildebolt C, Civitelli R.(2017)  Oral Manifestations of Metabolic Bone Diseases. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 8th Edition. (Accepted)
  • Cawthorn WP, Scheller EL. (2017) Editorial: Bone Marrow Adipose Tissue: Formation, Function, and Impact on Health and Disease. Front Endocrinol (Lausanne). 2017 May 29;8:112. 
  • Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ. (2017) Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood. Circ Res. 2017 Sep 1;121(6):662-676. 

2016

  • Cawthorn WP*, Scheller EL, Parlee SD, Pham HA, Learman BS, Redshaw CM, Sulston RJ, Burr AA, Das AK, Simon BR, Mori H, Bree AJ, Schell B, Krishnan V, MacDougald OA. (2016) Expansion of Bone Marrow Adipose Tissue During Caloric Restriction Is Associated With Increased Circulating Glucocorticoids and Not With Hypoleptinemia. Endocrinology. 157(2):508-521. PMCID: PMC4733126
  • Scheller EL*, Khoury B, Moller KL, Wee NK, Khandaker S, Kozloff KM, Abrishami SH, Zamarron BF, Singer K. (2016) Changes in skeletal integrity and marrow adiposity during high-fat diet and after weight-loss. Front Endocrinol. Jul 27;7:102. PMCID: PMC4961699
  • Walji TA*, Turecamo SE*, Sanchez AC, Anthony BA, Abou-Ezzi G, Scheller EL, Link DC, Mecham RP, Craft CS. (2016) Marrow adipose tissue expansion coincides with insulin resistance in MAGP1-deficient mice. Front Endocrinol. Jun 30;7:87. PMCID: PMC4928449
  • Sulston RJ, Learman BS, Zhang B, Scheller EL, Parlee SD, Simon BR, Mori H, Bree AJ, Wallace RJ, Krishnan V, MacDougald OA, Cawthorn WP. (2016) Increased circulating adiponectin in response to thiazolidinediones: investigating the role of bone marrow adipose tissue. Front Endocrinol. Sep 21;7:128. PMCID: PMC5030308
  • Scheller EL*, Burr A, MacDougald OA, Cawthorn WP. (2016) Inside out: Bone marrow adipose tissue as a source of circulating adiponectin. Adipocyte. DOI: 10.1080/21623945.2016.1149269
  • Scheller EL*, Cawthorn WP, Burr AA, Horowitz MC, MacDougald OA. (2016) Marrow adipose tissue: Trimming the Fat. Trends Endocrinol Metab. 27(6):392-403. PMCID: PMC4875855
  • Craft CS* and Scheller EL. (2016) Evolution of the Marrow Adipose Tissue Microenvironment. Calcif Tissue Int. Doi: 10.1007/s00223-016-0168-9
  • Walji TA, Turecamo SE, DeMarsilis AJ, Sakai LY, Mecham RP, Craft CS.(2016) Characterization of metabolic health in mouse models of fibrillin-1 perturbation. Matrix Biol. Sep;55:63-76.
  • Maedeker JA, Stoka KV, Bhayani SA, Gardner WS, Bennett L, Procknow JD, Staiculescu MC, Walji TA, Craft CS, Wagenseil JE.(2016) Hypertension and decreased aortic compliance due to reduced elastin amounts do not increase atherosclerotic plaque accumulation in Ldlr-/- mice. Atherosclerosis. Jun;249:22-9.