Dr. Scheller was elected to serve as a 2020 - 2022 board member for the International Society of Bone Morphometry (ISBM). She will work with the society and board to develop the field of skeletal imaging and morphology, including hosting the 2022 ISBM meeting in Denmark.
Mr. Beeve was selected as a recipient of the Department of Bioengineering travel award to attend the BMES conference in San Diego, CA where he will present his work on the acute and chronic regulation of bone by bioelectric stimulation of the sciatic nerve. Congratulations Alec!
Ms. Ivana Shen was awarded a 2020 BioSURF fellowship to pursue her work on the relationship between nerve quality and bone health in mice and humans with diabetes. Congratulations, Ivana!
Dr. Scheller was hosted by Dr. Tamara Alliston and the to UCSF Department of Orthopaedic Surgery to present the ongoing work in the laboratory pertaining to neural regulation of skeletal pathophysiology as part of the CCMBM seminar series. She then traveled to the UCLA School of Dentistry to visit with Dr. Paul Krebsbach and to […]
David Shin is currently a junior and was previously majoring in Economics and Accounting at Washington University in St. Louis prior to following the call to change his major to Biology. We welcome David to the lab and look forward to working with him to develop his scientific skills.
Implantable and wearable biosensors that enable monitoring of biophysical and biochemical parameters over long durations are highly attractive for early and presymptomatic diagnosis of pathological conditions and timely clinical intervention. Poor stability of antibodies used as biorecognition elements and the lack of effective methods to refresh the biosensors upon demand without severely compromising the functionality […]
Adipocytes within the skeleton are collectively termed bone marrow adipose tissue (BMAT). BMAT contributes to peripheral and local metabolism, however, its capacity for cell-autonomous expression of uncoupling protein 1 (UCP1), a biomarker of beige and brown adipogenesis, remains unclear. To overcome this, Ucp1-Cre was used to drive diphtheria toxin expression in cells expressing UCP1 (Ucp1Cre+/DTA+). Despite […]
A warm welcome to two new trainees. Dr. Alexander Ahmadi joins us from the Saint Louis University (SLU) periodontics residency program. Dr. Ahmadi will be working with us on the oral biosensor project. Xiao Zhang is currently visiting as a rotation student from the BME program at Washington University. Xiao will investigate the properties and […]
Bone marrow adipose tissue (BMAT) is increased in both obesity and anorexia. This is unique relative to white adipose tissue (WAT), which is generally more attuned to metabolic demand. It suggests that there may be regulatory pathways that are common to both BMAT and WAT and also those that are specific to BMAT alone. The […]
Dr. Scheller attended the XIVth Congress of the International Society of Bone Morphometry as an invited speaker and enjoyed the opportunity to share our work on nerves in bone and neural regulation of bone marrow adiposity.