| Age-related dysregulation of the retinal transcriptome in African turquoise killifish Bergmans S, Noel NCL, Masin L, Harding EG, Krzywańska AM, De Schutter JD, Ayana R, Hu CK, Arckens L, Ruzycki PA#, MacDonald RB#, Clark BS#, Moons L#. Aging Cell. 2024 May 14:e14192. doi: 10.1111/acel.14192. Epub ahead of print. PMID: 38742929. # co-corresponding authors |  |
| Cell-specific Systemic Immune Signatures Associated with Treatment Burden in Neovascular Age-related Macular Degeneration Lin JB, Santeford A, Usmani D, Shah AV, Ruzycki PA#, Apte RS#. Ophthalmol Sci. 2023 Oct 11;4(2):100410. doi: 10.1016/j.xops.2023.100410. PMID: 38524380; PMCID: PMC10960064. # co-corresponding authors |  |
| A Cataract-Causing Mutation in the TRPM3 Cation Channel Disrupts Calcium Dynamics in the Lens Zhou Y, Bennett TM, Ruzycki PA, Guo Z, Cao YQ, Shahidullah M, Delamere NA, Shiels A. Cells. 2024 Jan 30;13(3):257. doi: 10.3390/cells13030257. PMID: 38334649; PMCID: PMC10854584. |  |
| Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration Lin JB, Santeford A, Colasanti JJ, Lee Y, Shah AV, Wang TJ, Ruzycki PA#, Apte RS#. Cell Rep Med. 2024 Jan 16;5(1):101353. doi: 10.1016/j.xcrm.2023.101353. PMID: 38232696; PMCID: PMC10829736. # co-corresponding authors |  |
| Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function Lee TJ, Sasaki Y, Ruzycki PA, Ban N, Lin JB, Wu HT, Santeford A, Apte RS. JCI Insight. 2024 Jan 16;9(4):e173707. doi: 10.1172/jci.insight.173707. PMID: 38227383; PMCID: PMC11143937. |  |
| Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms Zheng Y, Sun C, Zhang X, Ruzycki PA, Chen S. Elife. 2023 Nov 14;12:RP87147. doi: 10.7554/eLife.87147. PMID: 37963072; PMCID: PMC10645426. |  |
| Dysregulated CD200-CD200R signaling in early diabetes modulates microglia-mediated retinopathy Pfeifer CW, Walsh JT, Santeford A, Lin JB, Beatty WL, Terao R, Liu YA, Hase K, Ruzycki PA, Apte RS. Proc Natl Acad Sci U S A. 2023 Nov 7;120(45):e2308214120. doi: 10.1073/pnas.2308214120. Epub 2023 Oct 30. PMID: 37903272; PMCID: PMC10636339. |  |
| Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity Sun C, Ruzycki PA#, Chen S#. Sci Rep. 2023 Aug 9;13(1):12899. doi: 10.1038/s41598-023-39979-6. PMID: 37558693; PMCID: PMC10412641. # co-corresponding authors |  |
| Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis Lin JB, Shen X, Pfeifer CW, Shiau F, Santeford A, Ruzycki PA, Clark BS, Liu Q, Huang AJW, Apte RS. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2204134120. doi: 10.1073/pnas.2204134120. Epub 2023 Jan 3. PMID: 36595669; PMCID: PMC9926235. |  |
| Essential Functions of MLL1 and MLL2 in Retinal Development and Cone Cell Maintenance Sun C, Zhang X, Ruzycki PA, Chen S. Front Cell Dev Biol. 2022 Feb 9;10:829536. doi: 10.3389/fcell.2022.829536. PMID: 35223853; PMCID: PMC8864151. |  |
| A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq Shiau F, Ruzycki PA, Clark BS. Dev Biol. 2021 Oct;478:41-58. doi: 10.1016/j.ydbio.2021.06.005. Epub 2021 Jun 17. PMID: 34146533; PMCID: PMC8386138. |  |
| Mutation of the EPHA2 Tyrosine-Kinase Domain Dysregulates Cell Pattern Formation and Cytoskeletal Gene Expression in the Lens Zhou Y, Bennett TM, Ruzycki PA, Shiels A. Cells. 2021 Sep 30;10(10):2606. doi: 10.3390/cells10102606. PMID: 34685586; PMCID: PMC8534143. |  |
| Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages Santeford A, Lee AY, Sene A, Hassman LM, Sergushichev AA, Loginicheva E, Artyomov MN, Ruzycki PA, Apte RS. Elife. 2021 Aug 23;10:e66703. doi: 10.7554/eLife.66703. PMID: 34423778; PMCID: PMC8412946. |  |
| Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis Hassman LM, Paley MA, Esaulova E, Paley GL, Ruzycki PA, Linskey N, Laurent J, Feigl-Lenzen L, Springer L, Montana CL, Hong K, Enright J, James H, Artyomov MN, Yokoyama WM. Ophthalmol Sci. 2021 Mar;1(1):100010. doi: 10.1016/j.xops.2021.100010. Epub 2021 Mar 13. PMID: 35937550; PMCID: PMC9352144. |  |
| Atoh7-independent specification of retinal ganglion cell identity Brodie-Kommit J, Clark BS, Shi Q, Shiau F, Kim DW, Langel J, Sheely C, Ruzycki PA, Fries M, Javed A, Cayouette M, Schmidt T, Badea T, Glaser T, Zhao H, Singer J, Blackshaw S, Hattar S. Sci Adv. 2021 Mar 12;7(11):eabe4983. doi: 10.1126/sciadv.abe4983. PMID: 33712461; PMCID: PMC7954457. |  |
| Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease Ray TA, Cochran K, Kozlowski C, Wang J, Alexander G, Cady MA, Spencer WJ, Ruzycki PA, Clark BS, Laeremans A, He MX, Wang X, Park E, Hao Y, Iannaccone A, Hu G, Fedrigo O, Skiba NP, Arshavsky VY, Kay JN. Nat Commun. 2020 Jul 3;11(1):3328. doi: 10.1038/s41467-020-17009-7. PMID: 32620864; PMCID: PMC7335077. |  |
| AMIGO2 Scales Dendrite Arbors in the Retina Soto F, Tien NW, Goel A, Zhao L, Ruzycki PA, Kerschensteiner D. Cell Rep. 2019 Nov 5;29(6):1568-1578.e4. doi: 10.1016/j.celrep.2019.09.085. PMID: 31693896; PMCID: PMC6871773. |  |
Showing: All results