Ruzycki Lab

We are interested in fundamental mechanisms of gene regulation and their impacts on retinal development and disease.

Specifically, we are currently focussing on:

• Novel histone modifications
• Non-canonical histone isoforms
• Cell fate specification
• Epigenetic alterations in aging and disease
• Enhancer function
• and more!

We are grateful for the generous organizations that fund our research.

Current Lab Funding

• NIH/NEI (National Eye Institute) – R01 (1R01EY036368) to PAR.
• Research to Prevent Blindness – Career Development Award to PAR.
• The McDonnell Center for Cellular and Molecular Neurobiology – Small Grant Program award to PAR and Dr. Benjamin Garcia.

We are also funded for collaborative work with:

• Dr. Brian Clark
• Dr. Tom Ferguson
• Dr. Shiming Chen
• Dr. Phil Williams
• Dr. Carla Siegfried
• Drs. Joe Dougherty & Robi Mitra
• Drs. Qin Liu & Andrew Huang

Previous Funding

• Hope Center for Neurological Disorders – Pilot Grant award to PAR and Dr. Daniel Kerschensteiner.
• BrightFocus Foundation – Macular Degeneration Research Grant to PAR with Dr. Raj Apte.
• The McDonnell Genome Institute – Pilot Project award to PAR and Dr. Raj Apte.
• The Carl Marshall and Mildred Almen Reeves Foundation – Macular Degeneration Research Grants to PAR and PAR with Dr. Raj Apte.