https://orcid.org/0000-0002-7590-7390

https://www.researchgate.net/scientific-contributions/Linda-J-Richards-39483182

2023

Ha T, Burgess R, Newman M, Moey C, Mandelstam S, Gardner A, Ivancevic A, Pham D, Kumar R, Smith N, Patel C, Malone S, Ryan M, Calvert S, van Eyk Clare, Lardelli M, Berkovic S, Leventer R, Richards L, Corbett M. (2023). Aicardi syndrome Is a genetically heterogeneous disorder. Genes, 14:1565. PDF

Suárez R, Bluett T, McCullough MH, Avitan L, Black DA, Paolino A, Fenlon LR, Goodhill GJ, Richards LJ. (2023). Cortical activity emerges in region-specific patterns during early brain development. Proceedings of the National Academy of Sciences 2023-05-30. PDF

Knight JL, Barker MS, Edwards TJ, Barnby JM, Richards LJ, Robinson GA. (2023). Mirror movements and callosal dysgenesis in a family with a DCC mutation: Neuropsychological and neuroimaging outcomes. Cortex, Apr;161:38-50. PDF

Palmer EE, Pusch M, Picollo A, Forwood C, Nguyen MH, Suckow V, Gibbons J, Hoff A, Sigfrid L, Megarbane A, Nizon M, Cogné B, Beneteau C, Alkuraya FS, Chedrawi A, Hashem MO, Stamberger H, Weckhuysen S, Vanlander A, … Kalscheuer VM. (2023). Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition. Mol Psychiatry, Feb;28(2):668-697. PDF

2022

Barnby JM, Dean RJ, Burgess H, Kim J, Teunisse AK, Mackenzie L, Richards LJ. (2022). Increased persuadability and credulity in people withcorpus callosum dysgenesis. Cortex, 155:251-263. PDF

Janowicz PW, Houston ZH, Bunt J, Fletcher NL, Bell CA, Cowin G, Howard CB, Taslima D, van Holthe NW, Prior A, Soh V, Ghosh S, Humphries J, Huda P, Mahler SM, Richards LJ, Thurecht KJ. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283. PDF

Wu D, Richards LJ, Zhao Z, Cao Z, Luo W, Shao W, Shi SH, Miller MI, Mori S, Blackshaw S, Zhang J. (2022). A diffusion MRI-based spatiotemporal continuum of the embryonic mouse brain for probing gene-neuroanatomy connections. Proc Natl Acad Sci U S A. Feb 15;119(7):e2111869119. PDF

Kozulin P, Suarez R, Zhao QY, Paolino A, Richards LJ, Fenlon LR. (2022). Divergent evolution of developmental timing in the neocortex revealed by marsupial and eutherian transcriptomes. Development, 149(3). PDF

Wickliffe CA, Geffen LB, McLachlan EM, Richards LJ, Rostas JAP. (2022). A brief history of the Australasian Neuroscience Society. Jnl of the History of the Neurosciences 31(4). PDF

2021

Lim JWC, Bunt J, Bridges CR, Moey C, Jacobs MT, Chen K-S, Richards LJ. (2021). EMX2 transcriptionally regulates Nfib expression in neural progenitor cells during early cortical development. bioRxiv 2021.12.26.474186. (Preprint). PDF

Quaglio G, Toia P, Moser EI, Karapiperis T, Amunts K, Okabe S, Poo M-M, Rah J-C, Koninck YD, Ngai J, Richards L, Bjaalie JG. (2021). The international brain initiative: Enabling collaborative science. Lancet Neurology, 20(12). PDF

Fenlon LR, Suarez R, Lynton Z, Richards LJ. (2021). The evolution, formation and connectivity of the anterior commissure. Seminars in Cell & Developmental Biology, 118:50-59. PDF

Morcom L, Edwards TJ, Rider E, Jones-Davis D, Lim JW, Chen KS, Dean RJ, Bunt J, Ye Y, Gobius I, Suárez R, Mandelstam S, Sherr EH, Richards LJ. (2021). DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation. Elife, May 4;10:e61618. PDF

Morcom L, Gobius I, Marsh AP, Suárez R, Lim JW, Bridges C, Ye Y, Fenlon LR, Zagar Y, Douglass AM, Donahoo AS, Fothergill T, Shaikh S, Kozulin P, Edwards TJ, Cooper HM, IRC5 Consortium, Sherr EH, Chédotal A, Leventer RJ, Lockhart PJ, Richards LJ. (2021). DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife, Apr 19;10:e61769. PDF

Barker MS, Knight JL, Dean RJ, Mandelstam S, Richards LJ, Robinson GA. (2021). Verbal adynamia and conceptualization in partial rhombencephalosynapsis and corpus callosum dysgenesis. Cognitive and Behavioral Neurology, 34(1):38-52. PDF

Chen KS, Lynton Z, Lim JWC, Robertson T, Gronostajski RM, Bunt J, Richards LJ. (2021). NFIA and NFIB function as tumour suppressors in high-grade glioma in mice. Carcinogenesis, 42(3):357-368. PDF

2020

Edwards TJ, Fenlon LR, Dean RJ, Bunt J, IRC5 Consortium, Sherr EH, Richards LJ. (2020). Altered structural connectivity networks in a mouse model of complete and partial dysgenesis of the corpus callosum. Neuroimage, Aug 15;217:116868. PDF

Spencer-Smith M, Knight JL, Lacaze E, IRC5 Consortium; Depienne C, Lockhart PJ, Richards LJ, Heron D, Leventer RJ, Robinson GA. (2020). Callosal agenesis and congenital mirror movements: outcomes associated with DCC mutations. Dev Med Child Neurol, Jun;62(6):758-762. PDF

Houston ZH, Bunt J, Chen KS, Puttick S, Howard CB, Fletcher NL, Fuchs AV, Cui J, Ju Y, Cowin G, Song X, Boyd AW, Mahler SM, Richards LJ, Caruso F, Thurecht KJ, (2020). Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies. ACS Cent Sci, May 27;6(5):727-738. PDF

Paolino A, Fenlon LR, Kozulin P, Haines E, Lim JWC, Richards LJ, Suárez R. (2020). Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution. Proc Natl Acad Sci U S A. May 12;117(19):10554-10564. PDF

Szczupak D, Liu C, Yen CCC, Choi S-H, Meireles F, Victorino C, Richards L, Lent R, Silva AC, Tovar-Moll F. (2020). Long-distance aberrant heterotopic connectivity in a mouse strain with a high incidence of callosal anomalies. NeuroImage, 217, 116875. PDF

Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bézieau S, Blackburn PR, Bunt J, Burglen L, Campeau PM, Charles P, … Sherr EH. (2020). Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development. Neuron, May 6;106(3):404-420.e8. PDF

Spencer-Smith M, Knight JL, Lacaze E, Depienne C, Lockhart PJ, Richards LJ, Heron D, Leventer RJ, Robinson GA. (2020). Callosal agenesis and congenital mirror movements: Outcomes associated with DCC mutations. Dev Med Child Neurol, 62:758-762. PDF

International Brain Initiative. (2020). International brain initiative: An innovative framework for coordinated global brain research efforts. Neuron, Jan 22;105(2):212-216. PDF

Australian Brain Alliance. (2020). A neuroethics framework for the australian brain initiative. Neuron, Jan 8;105(1):201. PDF

Chen KS, Bridges CR, Lynton Z, Lim JWC, Stringer BW, Rajagopal R, Wong KT, Ganesan D, Ariffin H, Day BW, Richards LJ, Bunt J. (2020). Transcription factors NFIA and NFIB induce cellular differentiation in high-grade astrocytoma. Journal of Neuro-Oncology, 146(1):41-53. PDF

2019

Zenker M, Bunt J, Schanze I, Schanze D, Piper M, Priolo M, Gerkes EH, Gronostajski RM, Richards LJ, Vogt J, Wessels MW, Hennekam RC. (2019). Variants in nuclear factor I genes influence growth and development. American Journal of Medical Genetics Part C-Seminars in Medical Genetics, 181 (4):611-626. PDF

Pajtler KW, Wei Y, Okonechnikov K, Silva PBG, Vouri M, Zhang L, Brabetz S, Sieber L, Gulley M, Mauermann M, Wedig T, Mack N, Imamura Kawasawa Y, Sharma T, Zuckermann M, Andreiuolo F, Holland E, Maass K, Körkel-Qu H, … Kawauchi D. (2019). YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis. Nat Commun, Sep 2;10(1):3914. PDF

Friocourt F, Kozulin P, Belle M, Suárez R, Di-Poï N, Richards LJ, Giacobini P, Chédotal A. (2019). Shared and differential features of Robo3 expression pattern in amniotes. J Comp Neurol, Aug 15;527(12):2009-2029. PDF

Emery B, Mitew S, Gobius I, Fenlon LR, McDougall S, Hawkes D, Lulu Xing L, Bujalka H, Gundlach AL, Richards LJ, Kilpatrick TJ, Merson T, Foster A. (2019). Oligodendroglial responses to neuronal activity in the developing and adult CNS. Glia, 67, E52-E52. (Conference abstract). PDF

Hearne LJ, Dean RJ, Robinson GA, Richards LJ, Mattingley JB, Cocchi L. (2019). Increased cognitive complexity reveals abnormal brain network activity in individuals with corpus callosum dysgenesis. Neuroimage Clin, 21:101595. PDF

2018

Paolino, A.; Fenlon, L.R.; Suárez, R.; Richards, L.J. (2018). Transcriptional control of long-range cortical projections. Current Opinion in Neurobiology, 53:57-65. PDF

Schanze I, Bunt J, Lim JWC, Schanze D, Dean RJ, Alders M, Blanchet P, Attié-Bitach T, Berland S, Boogert S, Boppudi S, Bridges CJ, Cho MT, Dobyns WB, Donnai D, Douglas J, Earl DL, Edwards TJ, Faivre L, … Richards LJ. (2018). NFIB haploinsufficiency is associated with intellectual disability and macrocephaly. Am J Hum Genet, Nov 1;103(5):752-768. PDF

Suárez R, Paolino A, Fenlon LR, Morcom LR, Kozulin P, Kurniawan ND, Richards LJ. (2018). A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum. Proc Natl Acad Sci USA. Sep 18;115(38):9622-9627. PDF

Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey TJ, Essebier A, Vidovic D, Gladwyn-Ng I, Burne TH, Heng JI, Richards LJ, Gronostajski RM, Piper M. (2018). Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development, 145(14). PDF

Edwards TJ, Marsh APL, Lockhart PJ, Richards LJ, Leventer RJ. (2018). Teaching neuroImages: Imaging features of DCC-mediated mirror movements and isolated agenesis of the corpus callosum. Neurology, 91(9). PDF

da Silva RV, Johannssen HC, Wyss MT, Roome RB, Bourojeni FB, Stifani N, Marsh APL, Ryan MM, Lockhart PJ, Leventer RJ, Richards LJ, Rosenblatt B, Srour M, Weber B, Zeilhofer HU, Kania A. (2018). DCC Is required for the development of nociceptive topognosis in mice and humans. Cell Rep, Jan 30;22(5):1105-1114. PDF

Mitew S, Gobius I, Fenlon LR, McDougall SJ, Hawkes D, Xing YL, Bujalka H, Gundlach AL, Richards LJ, Kilpatrick TJ, Merson TD, Emery B. (2018). Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner. Nat Commun, Jan 22;9(1):306. PDF

Marsh APL, Edwards TJ, Galea C, Cooper HM, Engle EC, Jamuar SS, Méneret A, Moutard ML, Nava C, Rastetter A, Robinson G, Rouleau G, Roze E, Spencer-Smith M, Trouillard O, Billette de Villemeur T, Walsh CA, Yu TW; IRC5 Consortium; Heron D, Sherr EH, Richards LJ, Depienne C, Leventer RJ, Lockhart PJ. (2018). DCC mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome. Hum Mutat, Jan;39(1):23-39. PDF

Paolino A, Fenlon LR, Kozulin P, Richards LJ, Suárez R. (2018). Multiple events of gene manipulation via in pouch electroporation in a marsupial model of mammalian forebrain development. J Neurosci Methods, Jan 1;293:45-52. PDF

2017

Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M. (2017). Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol, Dec 15;432(2):286-297. PDF

Chen K-S, Lim JWC, Richards LJ, Bunt J. (2017). The convergent roles of the nuclear factor I transcription factors in development and cancer. Cancer Letters, 410:124-138. PDF

Bunt J, Osinski JM, Lim JW, Vidovic D, Ye Y, Zalucki O, O’Connor TR, Harris L, Gronostajski RM, Richards LJ, Piper M. (2017). Combined allelic dosage of Nfia and Nfib regulates cortical development. Brain Neurosci Adv, Nov 22;1:2398212817739433. PDF

Suárez R, Paolino A, Kozulin P, Fenlon LR, Morcom LR, Englebright R, O’Hara PJ, Murray PJ, Richards LJ. (2017). Development of body, head and brain features in the australian fat-tailed dunnart (sminthopsis crassicaudata; marsupialia: dasyuridae); A postnatal model of forebrain formation. PLoS One, Sep 7;12(9):e0184450. PDF

Chen KS, Harris L, Lim JWC, Harvey TJ, Piper M, Gronostajski RM, Bunt J. (2017). Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice. Journal of Comparative Neurology, 525(11):2465-2483. PDF

Chen KS, Richards LJ, Bunt J. (2017). The role of nuclear factor I transcription factors in glioma. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res, 77(13). (Abstract). PDF

Gobius I, Suárez R, Morcom L, Paolino A, Edwards TJ, Kozulin P, Richards LJ. (2017). Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. Neural Dev, May 30;12(1):9. PDF

Double KL, Richards LJ. (2017). Reducing the burden of neurological disease and mental illness. Medical Journal of Australia, 206(8):341-U374. PDF

Marsh AP, Heron D, Edwards TJ, Quartier A, Galea C, Nava C, Rastetter A, Moutard ML, Anderson V, Bitoun P, Bunt J, Faudet A, Garel C, Gillies G, Gobius I, Guegan J, Heide S, Keren B, Lesne F, … Depienne C. (2017). Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance. Nat Genet. Apr;49(4):511-514. PDF

Fenlon LR, Suárez R, Richards LJ. (2017). The anatomy, organisation and development of contralateral callosal projections of the mouse somatosensory cortex. Brain Neurosci Adv, Mar 8;1:2398212817694888. PDF

2016

Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey TJ, Essebier A, Vidovic D, Gladwyn-Ng I, Burne TH, Heng JI, Richards LJ, Gronostajski RM, Piper M. (2016). Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development, Dec 15;143(24):4620-4630. PDF

Michie PT, Badcock DR, Bartlett PF, Bekkers JM, Bourne JA, Castles A, Egan FG, Fornito A, Hannan AJ, Hickie IB, Mattingley JB, Richards LJ, Schofield PR, Shum DHK, Stuart GJ, Vickers JC, Vissel B.(2016). Australian brain alliance. Neuron, 92(3):597-600. PDF

Edwards TJ, Sherr EH, Barkovich AJ, Richards LJ. (2016). Reply: ARID1B mutations are the major genetic cause of corpus callosum anomalies in patients with intellectual disability. Brain, 2016 Nov 1;139(11):e65. PDF

Gobius I, Morcom L, Suárez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ. (2016). Astroglial-mediated remodeling of the interhemispheric midline Is required for the formation of the corpus callosum. Cell Rep, Oct 11;17(3):735-747. PDF

Kozulin P, Richards LJ. (2016). Axonal guidance: Making cConnections. In: Pfaff D, Volkow N. (eds). Neuroscience in the 21st Century. Springer, New York, NY. PDF

Lambo S, Bunt J, Schmidt C, Pfister SM, Richards LJ, Chavez L, Korshunov A, Kool M. (2016). Genome-wide profiling of embryonal tumors with multilayered rosettes (ETMR). Neuro Oncol. Jun; 18(3): iii9. (Conference abstract). PDF

Stringer BW, Bunt J, Day BW, Barry G, Jamieson PR, Ensbey KS, Bruce ZC, Goasdoué K, Vidal H, Charmsaz S, Smith FM, Cooper LT, Piper M, Boyd AW, Richards LJ. (2016). Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma. Oncotarget. May 17;7(20):29306-20. PDF

Liu CR, Li YH, Edwards TJ, Kurniawan ND, Richards LJ, Jiang TZ. (2016). Altered structural connectome in adolescent socially isolated mice. Neuroimage, 139, 259-270. PDF

2015

Morcom LR, Edwards TJ, Richards LJ. (2015). Cortical architecture, midline guidance, and tractography of 3D white matter tracts. In: Axons and Brain Architecture, 289-313 Editor: Rockland K.S. Publisher: Elsevier. PDF

Kozulin P, Almarza G, Gobius I, Richards LJ. (2016). Investigating early formation of the cerebral cortex by in utero electroporation: Methods and protocols. In: Walker, D. (eds). Prenatal and Postnatal Determinants of Development. Neuromethods, vol 109. Humana Press, New York, NY. PDF

Lim JW, Donahoo AL, Bunt J, Edwards TJ, Fenlon LR, Liu Y, Zhou J, Moldrich RX, Piper M, Gobius I, Bailey TL, Wray NR, Kessaris N, Poo MM, Rubenstein JL, Richards LJ. (2015). EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex. Development, Nov 1;142(21):3746-57. PDF

Heng YH, Zhou B, Harris L, Harvey T, Smith A, Horne E, Martynoga B, Andersen J, Achimastou A, Cato K, Richards LJ, Gronostajski RM, Yeo GS, Guillemot F, Bailey TL, Piper M. (2015). NFIX regulates proliferation and migration within the murine SVZ neurogenic niche. Cereb Cortex, Oct;25(10):3758-78. PDF

Tsuyama J, Bunt J, Richards LJ, Iwanari H, Mochizuki Y, Hamakubo T, Shimazaki T, Okano H. (2015). MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells. Stem Cell Reports, Sep 8;5(3):365-77. PDF

Aggarwal M, Gobius I, Richards LJ, Mori S. (2015). Diffusion MR microscopy of cortical development in the mouse embryo. Cereb Cortex, 15 Jul;25(7):1970-80. PDF

Bunt J, Lim JW, Zhao L, Mason S, Richards LJ. (2015). PAX6 does not regulate Nfia and Nfib expression during neocortical development. Sci Rep, May 29;5:10668. PDF

Fenlon LR, Richards LJ. (2015). Contralateral targeting of the corpus callosum in normal and pathological brain function. Trends in Neurosciences, 38(5), 264-272. PDF

Fenlon LR, Liu S, Gobius I, Kurniawan ND, Murphy S, Moldrich RX, Richards LJ. (2015). Formation of functional areas in the cerebral cortex is disrupted in a mouse model of autism spectrum disorder. Neural Dev, Apr 3;10:10. PDF

2014

Faridar A, Jones-Davis D, Rider E, Li J, Gobius I, Morcom L, Richards LJ, Sen S, Sherr EH. (2014). Mapk/Erk activation in an animal model of social deficits shows a possible link to autism. Mol Autism. Dec 22;5:57. PDF

Schmidt ERE, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AS, Lilleväli K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ. (2014). Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron, Jul 16;83(2):372-387. PDF

Suárez R, Gobius I, Richards LJ. (2014). Evolution and development of interhemispheric connections in the vertebrate forebrain. Front Hum Neurosci, Jul 14;8:497. PDF

Suárez R, Fenlon LR, Marek R, Avitan L, Sah P, Goodhill GJ, Richards LJ. (2014). Balanced interhemispheric cortical activity is required for correct targeting of the corpus callosum. Neuron, Jun 18;82(6):1289-98. PDF

Edwards TJ, Sherr EH, Barkovich AJ, Richards LJ. (2014). Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes. Brain, Jun;137(Pt 6):1579-613. PDF

Srivatsa S, Parthasarathy S, Britanova O, Bormuth I, Donahoo AL, Ackerman SL, Richards LJ, Tarabykin V. (2014). Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation. Nat Commun, Apr 17;5:3708. PDF

Piper M, Barry G, Harvey TJ, McLeay R, Smith AG, Harris L, Mason S, Stringer BW, Day BW, Wray NR, Gronostajski RM, Bailey TL, Boyd AW, Richards LJ. (2014). NFIB- mediated repression of the epigenetic factor Ezh2 regulates cortical development. J Neurosci, Feb 19;34(8):2921-30. PDF

Clark CE, Richards LJ, Stacker SA, Cooper HM. (2014). Wnt5a induces Ryk-dependent and -independent effects on callosal axon and dendrite growth. Growth Factors, Feb;32(1):11-7. PDF

Heng YH, McLeay RC, Harvey TJ, Smith AG, Barry G, Cato K, Plachez C, Little E, Mason S, Dixon C, Gronostajski RM, Bailey TL, Richards LJ, Piper M. (2014). NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis. Cereb Cortex, Jan;24(1):261-79. PDF

Fothergill T, Donahoo ALS, Douglass A, Zalucki O, Yuan JJ, Shu TZ, Goodhill GJ, Richards LJ. (2014). Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating slit2-mediated repulsion. Cerebral Cortex, 24(5):1138-1151. PDF

2013

Lu T, Chen R, Cox TC, Moldrich RX, Kurniawan N, Tan G, Perry JK, Ashworth A, Bartlett PF, Xu L, Zhang J, Lu B, Wu M, Shen Q, Liu Y, Richards LJ, Xiong Z. (2013). X-linked microtubule-associated protein, mid1, regulates axon development. Proc Natl Acad Sci USA. Nov 19;110(47):19131-6. PDF

Huang H, Jeon T, Sedmak G, Pletikos M, Vasung L, Xu X, Yarowsky P, Richards LJ, Kostovic I, Sestan N, Mori S. (2013). Coupling diffusion imaging with histological and gene expression analysis to examine the dynamics of cortical areas across the fetal period of human brain development. Cereb Cortex, Nov;23(11):2620-31. PDF

Zhou J, Wen Y, She L, Sui YN, Liu L, Richards LJ, Poo MM. (2013). Axon position within the corpus callosum determines contralateral cortical projection. Proc Natl Acad Sci USA. Jul 16;110(29):E2714-23. PDF

Stegeman S, Jolly LA, Premarathne S, Gecz J, Richards LJ, Mackay-Sim A, Wood SA. (2013). Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis. PLoS One, Jul 5;8(7):e68287. PDF

Harris L, Dixon C, Cato K, Heng YH, Kurniawan ND, Ullmann JF, Janke AL, Gronostajski RM, Richards LJ, Burne TH, Piper M. (2013). Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice. PLoS One, 13 Jun 11;8(6):e65478. PDF

2012

Richards LJ. (2012). Wiring the developing brain. International Jnl of Developmental Neuroscience, 30 (8):637- 37. (Conference abstract). PDF

Plachez C, Cato K, McLeay RC, Heng YHE, Bailey TL, Gronostasjki RM, Richards LJ, Puche AC, Piper M. (2012). Expression of Nuclear Factor One A and -B in the Olfactory Bulb. Journal of Comparative Neurology, 520 (14):3135-3149. PDF

Subramanian L, Sarkar A, Shetty AS, Muralidharan B, Padmanabhan H, Piper M, Monuki ESM, Bach I, Gronostajski RM, Richards LJ, Tole S. (2012). Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus. International Journal of Developmental Neuroscience, 30(8):690-690. PDF

Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ. (2012). Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol, May 1;365(1):36-49. PDF

Shekarabi M, Moldrich RX, Rasheed S, Salin-Cantegrel A, Laganière J, Rochefort D, Hince P, Huot K, Gaudet R, Kurniawan N, Sotocinal SG, Ritchie J, Dion PA, Mogil JS, Richards LJ, Rouleau GA. (2012). Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum. J Neurosci, Mar 14;32(11):3865-76. PDF

Heng YH, Barry G, Richards LJ, Piper M. (2012). Nuclear factor I genes regulate neuronal migration. Neurosignals, 20(3):159-67. PDF

2011

Piper M, Harris L, Barry G, Heng YH, Plachez C, Gronostajski RM, Richards LJ. (2011). Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum. J Comp Neurol, Dec 1;519(17):3532-48. PDF

Moldrich RX, Mezzera C, Holmes WM, Goda S, Brookfield SJ, Rankin AJ, Barr E, Kurniawan N, Dewar D, Richards LJ, López-Bendito G, Iwata T. (2011). Fgfr3 regulates development of the caudal telencephalon. Dev Dyn, Jun;240(6):1586-99. PDF

Thompson AW, Pujic Z, Richards LJ, Goodhill GJ. (2011). Cyclic nucleotide-dependent switching of mammalian axon guidance depends on gradient steepness. Molecular and Cellular Neuroscience, 47(1):45-52. PDF

Stringer BW, Day BW, Barry G, Piper M, Jamieson, PR, Ensbey KS, Charmsaz S, Boyd AW, Richards LJ. (2011). The gliogenesis initiation factor nuclear factor IB induces differentiation and inhibits growth of glioblastoma.  In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR. Cancer Res 2011;71(8). (Abstract). PDF

Chuang N, Mori S, Yamamoto A, Jiang H, Ye X, Xu X, Richards LJ, Nathans J, Miller MI, Toga AW, Sidman RL, Zhang J. (2011). An MRI-based atlas and database of the developing mouse brain. Neuroimage, Jan 1;54(1):80-9. PDF

2010

Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ. (2010). Molecular regulation of the developing commissural plate. J Comp Neurol, Sep 15;518(18):3645-61. PDF

Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ. (2010). NFIA controls telencephalic progenitor cell differentiation through repression of the notch effector Hes1. J Neurosci, Jul 7;30(27):9127-39. PDF

Moldrich RX, Pannek K, Hoch R, Rubenstein JL, Kurniawan ND, Richards LJ. (2010). Comparative mouse brain tractography of diffusion magnetic resonance imaging. Neuroimage, Jul 1;51(3):1027-36. PDF

Chédotal A, Richards LJ. (2010). Wiring the brain: the biology of neuronal guidance. Cold Spring Harb Perspect Biol, Jun;2(6):a001917. PDF

2009

Piper M, Moldrich RX, Lindwall C, Little E, Barry G, Mason S, Sunn N, Kurniawan ND, Gronostajski RM, Richards LJ. (2009). Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Neural Dev, Dec 4;4:43. PDF

Donahoo A-LS, Richards LJ. (2009). Understanding the mechanisms of callosal development through the use of transgenic mouse models. Seminars in Pediatric Neurology. 16(3):127-142. PDF

Piper M, Plachez C, Zalucki O, Fothergill T, Goudreau G, Erzurumlu R, Gu C, Richards LJ. (2009). Neuropilin 1-sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum. Cereb Cortex, Jul;19 (Suppl 1):i11-21. PDF

Mortimer D, Feldner J, Vaughan T, Vetter I, Pujic Z, Rosoff WJ, Burrage K, Dayan P, Richards LJ, Goodhill GJ. (2009). A Bayesian model predicts the response of axons to molecular gradients. Proc Natl Acad Sci USA. Jun 23;106(25):10296-301. PDF

McGrath JJ, Richards LJ. (2009). Why schizophrenia epidemiology needs neurobiology–and vice versa. Schizophr Bull, May;35(3):577-81. PDF

Huang H, Xue R, Zhang J, Ren T, Richards LJ, Yarowsky P, Miller MI, Mori S. (2009). Anatomical characterization of human fetal brain development with diffusion tensor magnetic resonance imaging. J Neurosci, Apr 1;29(13):4263-73. PDF

Kumbasar A, Plachez C, Gronostajski RM, Richards LJ, Litwack ED. (2009). Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei. Journal of Comparative Neurology, 513 (1):98-112. PDF

2008

Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ. (2008). Specific glial populations regulate hippocampal morphogenesis. J Neurosci, Nov 19;28(47):12328-40. PDF

Plachez C, Lindwall C, Sunn N, Piper M, Moldrich RX, Campbell CE, Osinski JM, Gronostajski RM, Richards LJ. (2008). Nuclear Factor I gene expression in the developing forebrain. Journal of Comparative Neurology, 508 (3):385-401. PDF

Mason S, Piper M, Gronostajski RM, Richards LJ. (2009). Nuclear Factor One Transcription Factors in CNS Development. Mol Neurobiol, 39:10–23. PDF

Campbell CE, Piper M, Plachez C, Yeh YT, Baizer JS, Osinski JM, Litwack ED, Richards LJ, Gronostajski RM. (2008). The transcription factor Nfix is essential for normal brain development. BMC Dev Biol, May 13;8:52. PDF

Plachez C, Andrews W, Liapi A, Knoell B, Drescher U, Mankoo B, Zhe L, Mambetisaeva E, Annan A, Bannister L, Parnavelas JG, Richards LJ, Sundaresan V. (2008). Robos are required for the correct targeting of retinalganglion cell axons in the visual pathway of the brain. Molecular and Cellular Neuroscience, 37(4):719-730. PDF

Mortimer D, Fothergill T, Pujic Z, Richards LJ, Goodhill GJ. (2008). Growthcone chemotaxis. Trends in Neurosciences, 31(2):90-98. PDF

Piper M, Dawson A-LS, Lindwall C, Barry G, Plachez C, Richards LJ. (2008). Emx and Nfi Genes Regulate Cortical Development and Axon Guidance in the Telencephalon. Cortical Development: Genes and Genetic Abnormalities 288.(Abstract) PDF

2007

Ren T, Zhang J, Plachez C, Mori S, Richards LJ. (2007). Diffusion tensor magnetic resonance imaging and tract-tracing analysis of probst bundle structure in Netrin1- and DCC-deficient mice. J Neurosci, Sep 26;27(39):10345-9. PDF

Paul LK, Brown WS, Adolphs R, Tyszka JM, Richards LJ, Mukherjee P, Sherr EH. (2007). Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity. Nat Rev Neurosci, Apr;8(4):287-99. PDF

Lindwall C, Fothergill T, Richards LJ. (2007). Commissure formation in the mammalian forebrain. Current Opinion in Neurobiology, 17 (1), 3-14. PDF

2006

Zhang, Jiangyang; Richards, Linda J.; Miller, Michael. I.; Yarowsky, Paul; van Zijl, Peter; Mori, Susumu. (2006). Characterization of mouse brain and its development using diffusion tensor imaging and computational techniques. 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vols 1-15. PDF

Andrews W, Liapi A, Plachez C, Camurri L, Zhang J, Mori S, Murakami F, Parnavelas JG, Sundaresan V, Richards LJ. (2006). Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. Development, Jun;133(11):2243-52. PDF

Shen WB, Plachez C, Mongi AS, Richards LJ. (2006). Identification of candidate genes at the corticoseptal boundary during development. Gene Expression Patterns, 6(5):471-481. PDF

Ren T, Anderson A, Shen WB, Huang H, Plachez C, Zhang J, Mori S, Kinsman SL, Richards LJ. (2006). Imaging, anatomical, and molecular analysis of callosal formation in the developing human fetal brain. Anat Rec A Discov Mol Cell Evol Biol, Feb;288(2):191-204. PDF

Huang H, Zhang J, Wakana S, Zhang W, Ren T, Richards LJ, Yarowsky P, Donohue P, Graham E, van Zijl PCM, Mori S. (2006). White and gray matter development in human fetal, newborn and pediatric brains. NeuroImage, 33(1):27-38. PDF

2005

Zhang J, Chen YB, Hardwick JM, Miller MI, Plachez C, Richards LJ, Yarowsky P, van Zijl P, Mori S. (2005). Magnetic resonance diffusion tensor microimaging reveals a role for bcl-x in brain development and homeostasis. J Neurosci, Feb 23;25(8):1881-8. PDF

Zhang J, Miller MI, Plachez C, Richards LJ, Yarowsky P, van Zijl P, Mori S. (2005). Mapping postnatal mouse brain development with diffusion tensor microimaging. NeuroImage, 26(4). PDF

Plachez C, Richards LJ. (2005). Mechanisms of axon guidance in the developing nervous system. Current Topics in Developmental Biology, Academic Press, 69:267-346. PDF

Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ, Gronostajski RM. (2005). The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol Cell Biol, Jan;25(2):685-98. PDF

2004

Richards LJ, Plachez C, Ren T. (2004). Mechanisms regulating the development of the corpus callosum and its agenesis in mouse and human. Clinical Genetics, 66(4):276-289. PDF

Rosoff WJ, Urbach JS, Esrick MA, McAllister RG, Richards LJ, Goodhill GJ. (2004). A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients. Nat Neurosci, 7:678–682. PDF

2003

Shu T, Sundaresan V, McCarthy MM, Richards LJ. (2003). Slit2 guides both precrossing and postcrossing callosal axons at the midline in vivo. J Neurosci, Sep 3;23(22):8176-84. PDF

Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD. (2003). Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Dev Cell, Jul;5(1):45-57. PDF

Shu T, Li Y, Keller A, Richards LJ. (2003). The glial sling is a migratory population of developing neurons. Development, Jul;130(13):2929-37. PDF

Leingärtner A, Richards LJ, Dyck RH,  Akazawa C, O’Leary DDM. (2003). Cloning and cortical expression of rat Emx2 and adenovirus-mediated overexpression to assess its regulation of area-specific targeting of thalamocortical axons. Cerebral Cortex, 13(6):648–660. PDF

Zhang J, Richards LJ, Yarowsky P, Huang H, van Zijl PCM, Mori S. (2003). Three-dimensional anatomical characterization of the developing mouse brain by diffusion tensor microimaging. NeuroImage, 20(3):1639-1648. PDF

Shu TZ, Puche AC, Richards LJ. (2003). Development of midline glial populations at the corticoseptal boundary. Journal of Neurobiology, 57(1):81-94. PDF

Shu T, Butz KG, Plachez C, Gronostajski RM, Richards LJ. (2003). Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. J Neurosci, Jan 1;23(1):203-12. PDF

2002

Richards LJ. (2002). Axonal pathfinding mechanisms at the cortical midline and in the development of the corpus callosum. Braz J Med Biol Res, Dec;35(12):1431-9. PDF

Richards LJ. (2002). Surrounded by Slit–how forebrain commissural axons can be led astray. Neuron, Jan 17;33(2):153-5. PDF

2001

Shu T, Richards LJ. (2001). Cortical axon guidance by the glial wedge during the development of the corpus callosum. J Neurosci, Apr 15;21(8):2749-58. PDF

Shu TZ, Shen WB, Richards LJ. (2001). Development of the perforating pathway: An ipsilaterally projecting pathway between the medial septum/diagonal band of broca and the cingulate cortex that intersects the corpus callosum. Journal of Comparative Neurology, 436(4):411-422. PDF

Rash BG, Richards LJ. (2001). A role for cingulate pioneering axons in the development of the corpus callosum. Journal of Comparative Neurology, 434(2):147-157. PDF

2000

Ivic, L., Pyrski, M., Margolis, J. et al. (2000). Adenoviral vector-mediated rescue of the OMP-null phenotype in vivoNat Neurosci, 3:1113–1120 . PDF

Gad JM, Keeling SL, Shu T, Richards LJ, Cooper H. (2000). The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. Experimental Eye Research, 70(6). PDF

Shu T, Valentino KM, Seaman C, Cooper HM, Richards LJ. (2000). Expression of the netrin-1 receptor, deleted in colorectal cancer (DCC), is largely confined to projecting neurons in the developing forebrain. Jnl of Comparitive Neurology, 416(2):201-212. PDF

1999

Goodhill GJ, Richards LJ. (1999). Retinotectal maps: molecules, models and misplaced data. Trends Neurosci, Dec;22(12):529-34. PDF

1998

Tuttle R, Braisted JE, Richards LJ, O’Leary DDM. (1998). Retinal axon guidance by region-specific cues in diencephalon. Development, 125(5):791-801. PDF

1997

Richards LJ, Koester SE, Tuttle R, O’Leary DD. (1997). Directed growth of early cortical axons is influenced by a chemoattractant released from an intermediate target. J Neurosci, Apr 1;17(7):2445-58. PDF

1996

Moriyoshi K, Richards LJ, Akazawa C, O’Leary DD, Nakanishi S. (1996). Labeling neural cells using adenoviral gene transfer of membrane-targeted GFP. Neuron, Feb;16(2):255-60. PDF

Richards LJ, Kilpatrick TJ, Dutton R, Tan S-S, Gearing DP, Bartlett PF, Murphy M. (1996). Leukaemia inhibitory factor or related factors promote the differentiation of neuronal and astrocytic precursors within the developing murine spinal cord. European Journal of Neuroscience, 8(2):291-299. PDF

1995

Richards LJ, Murphy M, Dutton R, Kilpatrick TJ, Puche AC, Key B, Tan SS, Talman PS, Bartlett PF. (1995). Lineage specification of neuronal precursors in the mouse spinal cord. Proc Natl Acad Sci USA. Oct 24;92(22):10079-83. PDF

Bartlett PF, Richards LR, Kilpatrick TJ, Talman PT, Bailey KA, Brooker GJ, Dutton R, Koblar SA, Nurcombe V, Ford MO, Cheema SS, Likiardopoulos V, Barrett G, Murphy M. (1995). Factors regulating the differentiation of neural precursors in the forebrain. Ciba Found Symp. 93:85-99; discussion 117-26. PDF

Bartlett, PF, Richards, LR, Kilpatrick, TJ, Talman, PS, Bailey, KA, Brooker, Gjf, Dutton, R, Koblar, S, Nurcombe, V, Ford, M, Cheema, SS, Likiardopoulos, V, and Murphy, M (1995). Regulation of Neural Precursor Differentiation in the Embryonic and Adult Forebrain. Clinical and Experimental Pharmacology and Physiology, 22(8):559-562. PDF

Kilpatrick TJ, Richards LJ, Bartlett PF. (1995). The Regulation of Neural Precursor Cells within the Mammalian Brain. Molecular and Cellular Neuroscience, 6(1):2-15. PDF

1994

Cheema SS, Richards LJ, Murphy M. (1994). Leukemia inhibitory factor rescues motoneurons from axotomy-induced cell death. NeuroReport, 5(8):989-992. PDF

Cheema SS, Richards L, Murphy M, Bartlett PF. (1994). Leukemia inhibitory factor prevents the death of axotomised sensory neurons in the dorsal root ganglia of the neonatal rat. Journal of Neuroscience Research, 37(2):213-218. PDF

Bartlett PF, Kilpatrick TJ, Richards LJ, Talman PS, Murphy M. (1994). Regulation of the early development of the nervous system by growth factors. Pharmacology & Therapeutics, 64(3):371-393. PDF

1993

Rosenfeld JV, Richards LJ, Bartlett PF. (1993). Mutant mouse cerebellum does not provide specific signals for the selective migration and development of transplanted Purkinje cells. Neuroscience Letters, 155(1):19-23. PDF

1992

Richards LJ, Kilpatrick TJ, Bartlett PF. (1992). De novo generation of neuronal cells from the adult mouse brain. Proc Natl Acad Sci U S A. Sep 15;89(18):8591-5. PDF

Richards LJ, Kilpatrick TJ, Bartlett PF, Murphy M. (1992). Leukemia inhibitory factor promotes the neuronal development of spinal cord precursors from the neural tube. Journal of Neuroscience Research 33:476-484. PDF

Bartlett PF, Drago JK, Trevor J, Richards LJ, Wookey P, Murphy M. (1992). Regulation of the early development of the nervous system by growth factors. In: Development of the Central Nervous System in Vertebrates. Edited by S. C. Sharma and A. M. Goffinet. Boston, MA, United States: Springer. PDF