2024

Duong, K., Moss, E., Reichhardt, C. Solid-state NMR compositional analysis of sputum from people with cystic fibrosis. Solid state Nuclear Magnetic Resonance 2024, https://doi.org/10.1016/j.ssnmr.2024.101975.

Fazio, N. T., Reichhardt, C. Structural biology: Proteobacterial accessories for diverse cellulose synthesis. Current Biology 2024, https://doi.org/10.1016/j.cub.2023.12.029.

Audio file of Dispatch article

2023

Amyx-Sherer, K., Reichhardt, C. Challenges and opportunities in elucidating the structures of biofilm exopolysaccharides: A case study of the Pseudomonas aeruginosa exopolysaccharide called Pel. Magnetic Resonance in Chemistry 2023, https://doi.org/10.1002/mrc.5405.

Audio file of Pel case study

Reichhardt, C. The Pseudomonas aeruginosa biofilm matrix protein CdrA has similarities to other fibrillar adhesin proteins. Journal of Bacteriology-Special Series: 2022 ASM Conference on Biofilms 2023, e00019-23.

Audio file of CdrA review

Pre-WashU

2023

Razvi, E., Whitfield, G.B., Reichhardt, C. et al. Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence. NPJ Biofilms Microbiomes 2023, 9, 7.

2022

Le Mauff, F., Razvi, E., Reichhardt, C. et al. The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine. Commun Biol 2022, 5, 502.

2021

Morris A.J., Jackson L., Cw Yau Y., Reichhardt C., Beaudoin T., Uwumarenogie S., Guttman K.M., Lynne Howell P., Parsek M.R., Hoffman L.R., Nguyen D., DiGiandomenico A., Guttman D.S., Wozniak D.J., Waters V.J. The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis. NPJ Biofilms Microbiomes 2021, 7, 63.

Jennings L.K., Dreifus J.E., Reichhardt C., Storek K.M., Secor P.R., Wozniak D.J., Hisert K.B., M.R. Parsek, Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies. Cell Reports 2021, 34, 108782.

2020

Limqueco E., Passos Da Silva D., Reichhardt C., Su F., Das D., Chen J., Srinivasan S., Convertine A., Skerrett S.J., Parsek M.R., Stayton P.S., and Ratner D.M., Mannose conjugated polymer targeting P. aeruginosa biofilms. ACS Infectious Diseases 2020, 6, 2866-2871.

Reichhardt C., Jacobs H.M., Matwichuk M., Wong C., Wozniak D.J., and M.R. Parsek, The versatile Pseudomonas aeruginosa biofilm matrix protein CdrA promotes aggregation through different extracellular EPS interactions. Journal of Bacteriology 2020, 202, e00216-20.

2019

Reichhardt C. and M.R. Parsek, Confocal laser scanning microscopy for analysis of Pseudomonas aeruginosa biofilm architecture and matrix localization. Frontiers Microbiology 2019, 10, 677.

Passos da Silva D., Matwichuk M.L., Townsend D.O., Reichhardt C., Lamba D., Wozniak D.J., and M.R. Parsek, The Pseudomonas aeruginosa lectin LecB binds to Psl and stabilizes the biofilm matrix. Nature Communications 2019, 10, 2183.

Reichhardt C., Joubert L.-M., Clemons K.V., Stevens D.A., and L. Cegelski, Integration of electron microscopy and solid-state NMR analysis for new views and compositional parameters of A. fumigatus biofilms. Medical Mycology 2019, 57, S239–S244.

2018

Reichhardt C., Wong C., Passos da Silva D., Wozniak D.J., and M.R. Parsek, CdrA interactions within the Pseudomonas aeruginosa biofilm matrix safeguard it from proteolysis and promote cellular packing. mBio 2018, 9, e01376-18.

Tseng B.S.*, Reichhardt C.*, Merrihew G.E., Harrison J.J., MacCoss M.J., and M.R. Parsek, A biofilm matrix-associated protease inhibitor protects Pseudomonas aeruginosa from proteolytic attack. mBio 2018, 9, e00543-18 [*co-first authors]

Reichhardt C.# and L. Cegelski#, The Congo red derivative FSB binds to curli amyloid fibers and specifically stains curliated E. coli. PLOS ONE 2018, 13, e0203226. [#co-corresponding authors]

2016

Reichhardt C., Stevens, D.A., and L. Cegelski, Fungal biofilm composition and opportunities in drug discovery. Future Medicinal Chemistry 2016, 8, 1455-1468.

Reichhardt C., McCrate O.A., Zhou X., Lee J., and L. Cegelski,Influence of the amyloid dye Congo red on curli, cellulose, and the extracellular matrix in E. coli during growth and matrix purification. Analytical and Bioanalytical Chemistry 2016, 408, 7709-7717.

2015

Reichhardt C.*, Jacobson A.*, Maher M., Uang J., McCrate O.A., Eckart M., and L. Cegelski, Congo red interactions with curli-producing E. coli and native curli amyloid fibers. PLOS ONE 2015, 10, e0140388. [*co-first authors]

Reichhardt C.*, Ferreira J.A.G.*, Joubert L.M., Clemons K.V., Stevens D.A., and L. Cegelski, Analysis of the Aspergillus fumigatus biofilm extracellular matrix by solid-state nuclear magnetic resonance. Eukaryotic Cell 2015, 14, 1064-1072. [*co-first authors]

Reichhardt C., Fong J. N., Yildiz F., and L. Cegelski, Characterization of the Vibrio cholerae extracellular matrix: a top-down solid-state NMR approachBiochimica Biophysica Acta- Biomembranes 2015, 1848, 378-383.

2014

Reichhardt C. and L. Cegelski, Solid-state NMR for bacterial biofilms. Molecular Physics 2014, 112, 887-894.

2013

McCrate O.A., Zhou X., Reichhardt C., and L. Cegelski, Sum of the parts:  composition and architecture of the bacterial extracellular matrixJournal of Molecular Biology 2013, 425, 4286-4294.

2011

Jolley C., Lucon J., Uchida M., Reichhardt C., Vaughn M., LaFrance B., and T. Douglas, Structure, dynamics, and solvation in a disordered metal-organic coordination polymer: a multiscale study. Journal of Coordination Chemistry 2011, 64, 4301-4317.

Reichhardt C., Uchida M., O’Neil A., Li R., Prevelige P., and T. Douglas, Templated assembly of organic-inorganic materials using the core shell structure of the P22 bacteriophage. Chemical Communications 2011, 47, 6326-6328.

O’Neil A., Reichhardt C., Johnson B., Prevelige P., and T. Douglas, Genetically programmed in vivo packaging of protein cargo and its controlled release from bacteriophage P22. Angewandte Chemie International Edition 2011, 50, 7425-7428.

2010

Jolley C., Uchida M., Reichhardt C., Harrington R., Kang S., Klem M., Parise J., and T. Douglas, Size and crystallinity in protein-templated inorganic nanoparticles. Chemistry of Materials 2010, 22, 4612–4618.

Uchida M., Kang S., Reichhardt C., Harlen K., and T. Douglas, The ferritin superfamily:  Supramolecular templates for materials synthesis, Biochimica Biophysica Acta-General Subjects 2010, 1800, 834-845.