Current Project Information
Client Information: Our client is UN&UP (https://www.unandup.com/) with our main point of contact being Michael Sabo (mes@unandup.com).
Need Statement: There is a need to shorten the time frostbite goes untreated and the time to localized drug delivery of a proprietary thrombolytic developed by UN&UP to improve frostbite patient treatment outcomes and increase extremity retention and function.
Project Scope: Physicians need a method to quickly and accurately deliver frostbite therapeutics to affected extremities where blood often coagulates. This timelier and more targeted therapeutic intervention utilizing a proprietary thrombolytic developed by UN&UP will improve patient outcomes allowing them to retain extremities and relevant function for a higher quality of life. The therapeutic localization device will be accessible to various orientations and sizes of digits and extremities, and the thrombolytic will reach extremities within 1 minute of device activation. Additionally, to test the validity of this device a realistic phantom reflecting the dynamics of extremity vasculature will be fabricated. A drug localization device, a realistic phantom, and all proper documentation to our client UN&UP by April 25, 2025.
Recent Activities
The team created CAD files for the limb stage with relative anthropometric data for wrist, arm, and hand sizes. The team decided to focus the solenoid and stage prototype on hands and fingers given their higher importance in quality of life and ease of accessibility for individual solenoids compared to toes; however, the spinning permanent magnet could still be applied to feet.
The team met with Sheila Ziobro of Parvus Microstructures about outsourcing the 3D printing of the microfluidic molds to reach resolutions smaller than what can be generated with UN&UPs printers.
The team continued to work on the Verification and Validation Report.
Future Steps
The team is awaiting further communication on Dr. Kells’s schedule, we have been in contact with her administrative secretary and expect a meeting to be set very soon.
Questions/Things to Look Into
None.