Publications, press, and support

Publications

  • Bandres MF, Gomes JL, & McPherson JG (2024). Intraspinal microstimulation of the ventral horn has therapeutically relevant cross-modal effects on nociception. Brain Communications, fcae280. https://doi.org/10.1093/braincomms/fcae280
  • Moreno Romero GN, Twyman AR, Bandres MF, & McPherson JG. (2024). Unintentionally intentional: unintended effects of spinal stimulation as a platform for multi-modal neurorehabilitation after spinal cord injury. Bioelectronic Medicine, 10(1), 12. https://doi.org/10.1186/s42234-024-00144-7
  • McPherson JG, & Bandres MF. (2023). Neural population dynamics reveal that motor-targeted intraspinal microstimulation preferentially depresses nociceptive transmission in spinal cord injury-related neuropathic pain. bioRxiv. https://10.1101/2023.07.27.550880.
  • Bandres MF†, Gomes JL, McPherson JG*(2023). Spinal cord injury constrains the variability of neuronal population activity despite the emergence of sensory hyperexcitability. (In final preparation). *corresponding author; †student author
  • McPherson JG*, Bandres MF† (2023). Scale-free dynamics of intraspinal local field potentials, but not spontaneous oscillations, reveal structural and functional organization of spinal networks. (In final preparation). *corresponding author; †student author
  • McPherson JG, Miller RR, Perlmutter SI, Fetz EE (2023). Operant conditioning of deep forebrain reward circuitry using an electrocorticogram-triggered recurrent neural-computer interface (in final preparation) DOI https://doi.org/10.1101/2024.09.10.612344.
  • Bandres MF†, Gomes JL, McPherson JG*(2023). Motor-targeted spinal stimulation promotes concurrent rebalancing of pathologic nociceptive transmission in chronic spinal cord injury. bioRxiv (and undergoing peer review) DOI: https://doi.org/10.1101/2023.04.12.536477. *corresponding author; †student author
  • Bandres MF†, Gomes JL, Moreno Romero GN†, Twyman AR†, McPherson JG* (2023). Precision neuromodulation: promises and challenges of spinal stimulation for multi-modal rehabilitation. Front. Rehab. Sci. V(4): 2023. doi: 10.3389/fresc.2023.1135593 *corresponding author; †student author
  • Bandres MF†, Gomes JL, McPherson JG*(2022). Spinal stimulation for motor rehabilitation immediately modulates nociceptive transmission. J Neural Engineering. 2022 Oct 13. doi: 10.1088/1741-2552/ac9a00. *corresponding author; †student author
  • Bandres MF†, Gomes J, McPherson JG* (2021). Spontaneous multimodal neural transmission suggests that adult spinal networks maintain an intrinsic state of readiness to execute sensorimotor behaviors. J Neuroscience. 2021 Sep 22;41(38):7978-7990. doi: 10.1523/JNEUROSCI.0662-21.2021.*corresponding author; †student author 
  • McPherson JG*, Bandres MF† (2021). Spontaneous neural synchrony links intrinsic spinal sensory and motor networks during unconsciousness. eLife. 2021;10:e66308 DOI: 10.7554/eLife.66308. *corresponding author; †student author
  • Moorjani S, McPherson JG, Perlmutter S (2019). Electrical Conditioning for Spike Timing-Dependent Plasticity of Neural Circuits. In: Jaeger D and Jung R (eds.) Encyclopedia of Computational Neuroscience. ISBN: 978-1-4614-6674-1.
  • Lemay M, McPherson JG* (2019). Spinal Interfaces: An Overview. In: Jaeger D and Jung R (eds.) Encyclopedia of Computational Neuroscience. ISBN: 978-1-4614-6674-1. *corresponding author
  • McPherson JG, Chen A, Ellis MD, Yao J, Heckman CJ, Dewald JPA (2019). Response to Letter to the Editor. J Physiol. 2019 Aug; 597(16): 4413-4414; DOI: 10.1113/JP278464.
  • McPherson JG*, Smith AC, Duben D†, Wasielewski M, McMahon K, Parrish TB, Elliott JM (2018). Short- and long-term reproducibility of diffusion-weighted magnetic resonance imaging of lower extremity musculature in asymptomatic individuals and a comparison to individuals with spinal cord injury. BMC Musculoskeletal Disorders. 2018 Dec 6th; 19:443. DOI: 10.1186/s12891-01802361-7.
  • McPherson JG, Stienen AH, Schmit BD, Dewald JPA (2018). Biomechanical parameters of the elbow stretch reflex in chronic hemiparetic stroke. Experimental Brain Research. 2018 Oct 1st; DOI: 10.1007/s00221-018-5389-x.
  • McPherson JG, Ellis MD, Harden RN, Carmona C, Drogos JM, Heckman CJ, Dewald JPA (2018). Neuromodulatory inputs to motoneurons contribute to the loss of independent joint control in chronic moderate to severe hemiparetic stroke. Front Neurol. 2018 Jun 21; 9:470. DOI: 10.3389/fneur.2018.00470.
  • McPherson JG, McPherson LM, Thompson CK, Ellis MD, Heckman CJ, Dewald JPA (2018). Altered neuromodulatory drive may contribute to exaggerated tonic vibration reflexes in chronic hemiparetic stroke. Front Hum Neurosci. 2018 Apr 9; 12:131. DOI: 10.3389/fnhum.2018.00131.
  • McPherson JG, Chen A, Ellis MD, Yao J, Heckman CJ, Dewald JPA (2018). Progressive recruitment of contralesional cortico-reticulospinal pathways drives impairment post-stroke. J Physiol. 2018 Apr 1; 596(7):1211-1225. DOI: 10.1113/JP274968.
  • McPherson JG, Stienen AH, Drogos JM, Dewald JPA (2018). Modification of spastic stretch reflexes at the elbow by flexion synergy expression in individuals with chronic, hemiparetic stroke. Arch Phys Med Rehabil. 2018 Mar; 99(3): 491-500; Epub 2017 Jul 24. DOI: 10.1016/j.apmr.2017.06.019.
  • Smith AC, Weber KA, Parrish TB, Hornby TG, Tysseling VM, McPherson JG, Wasielewski M, Elliott JM (2017). Ambulatory function in motor incomplete spinal cord injury: a magnetic resonance imaging study of spinal cord edema and lower extremity muscle morphometry. Spinal Cord. 2017 Jul; 55(7): 672-678. DOI: 10.1038/sc.2017.18.
  • Dewald JPA, Ellis MD, Acosta AM, McPherson JG, Stienen AH (2016). Implementation of impairment-based neurorehabilitation devices and technologies following brain injury. In: Dietz V, Reinkensmeyer DJ (eds.) Neurorehabilitation Technology: Springer, 2nd DOI: 10.1007/978-3-319-28603-7.
  • Elliott JM, Sudarshan D, Haxie C, Hoggarth M, McPherson JG, Sparks C, Weber K (2016). Advancements in imaging technology: do they (or will they) equate to advancements in our knowledge of recovery in whiplash? J Orthop Sports Phys Ther. 2016 Oct; 46(10):862-873. PMID: 27690846.
  • Smith AC, Knikou M, Yelick K, Alexander A, Murnane M, Kristelis A, Houmpavlis P, McPherson JG, Wasielewski M, Hoggarth M, Elliott (2016). MRI measures of fat infiltration in lower extremities following motor incomplete spinal cord injury: reliability and potential implications for muscle activation. Conf Proc IEEE Eng Med Biol Soc. 2016 Aug; 2016:5451-5456. DOI: 10.1109/EMBC.2016.7591960.
  • McPherson JG, Miller RR, Perlmutter SI (2015). Targeted, activity-dependent spinal stimulation produces long-lasting motor recovery in chronic cervical spinal cord injury. Proc Natl Acad Sci USA. 2015 Sept 29; 112(39): 12193-8. DOI: 10.1073/pnas.1505383112.
  • Smith AC, Parrish TB, Hoggarth MA, McPherson JG, Tysseling VM, Wasielewski M, Kim HE, Hornby TG, Elliott JM (2015). Potential associations between chronic whiplash and incomplete spinal cord injury. Spinal Cord Ser Cases. 2015; 1. pii: 15024. PMID: 27630770.
  • McPherson JG, Edwards WB, Prasad A, Troy KL, Griffith JW, Schnitzer TJ (2014). Dual energy x-ray absorptiometry of the knee in individuals with spinal cord injury: methodology and correlation with quantitative computed tomography. Spinal Cord. 2014 Nov; 52(11): 821-5. DOI: 10.1038/sc.2014.122.
  • Dewald JPA, Ellis MD, Acosta AM, McPherson JG, Stienen AH, (2012). Implementation of impairment-based neurorehabilitation devices and technologies following brain injury. In: Dietz V, Nef T, Rymer Z (eds.) Neurorehabilitation Technology: Chapter 19: 343-358. Springer, 1st edition. DOI: 10.1007/978-1-4471-2277-7.
  • McPherson JG, Stienen AH, Drogos JM, Dewald JPA (2011). The relationship between the flexion synergy and stretch reflexes in individuals with chronic hemiparetic stroke. IEEE Int Conf Rehabil Robot. 2011: 5975516. DOI: 10.1109/ICORR.2011.5975516.
  • Stienen AH, McPherson JG, Schouten AC, Dewald JPA (2011). The ACT-4D: a novel rehabilitation robot for the quantification of upper limb motor impairments following brain injury. IEEE Int Conf Rehabil Robot. 2011:5975460. DOI: 10.1109/ICORR.2011.5975460.
  • McPherson JG, Ellis MD, Heckman CJ, Dewald JPA (2008). Evidence for increased activation of persistent inward currents in individuals with chronic hemiparetic stroke. J Neurophysiol. 2008 Dec; 100(6): 3236-3243. DOI: 10.1152/jn.90563.2008

Press (selected)

  • “New research on the brain’s backup motor systems could open door to novel stroke therapies.” EurekAlert! (American Association for the Advancement of Science; AAAS). Feb. 14th, 2018.
  • “Study could lead to new therapies to improve movement control in stroke survivors.” The Medical News. Feb. 16th, 2018.
  • “New insights into stroke treatment.” Medindia. Feb. 16th, 2018.
  • Ozpinar A, Tempel ZJ, Monaco EA 3rd. “Targeted, activity-dependent spinal stimulation produces long-lasting motor recovery in chronic cervical spinal cord injury.” Commentary in 2016 Feb; 78(2): N18-9. doi: 10.1227/01.neu.0000479893.25489.47.
  • Nudo, RJ. “Rehabilitation: Boost for movement.” Nature, 527: 314-315, Sept 19th, 2015.
  • “Electric zaps help spinal-cord rehab.” Nature, 525: 428. Sept 24, 2015.
  • “New electrostatic stimulation technique improves damaged nerve function in rats.” Medical Xpress, Sept 15th, 2015.
  • “Stimulating damaged spines rewires rats for recovery.” IEEE Spectrum, Sept 14th, 2015.

Support

Active
  • CDMRP/DoD SC2101118P1, McPherson and Thompson (Co-PI’s): “Targeted spinal cord plasticity for alleviating SCI-related neuropathic pain.”
  • NIH/NINDS R01 NS111234, McPherson (PI): Research supplement to promote diversity in health-related research.
  • NIH/NINDS R01 NS111234, McPherson (PI): Administrative supplement to “Intraspinal microstimulation for multi-modal rehabilitation.” 
  • AHA 19IPLOI34760603, McPherson (PI): Administrative supplement to “Restorative neuroplasticity in brainstem motor pathways to enhance rehabilitation post-stroke.”
  • AHA 19IPLOI34760603, McPherson (PI): “Restorative neuroplasticity in brainstem motor pathways to enhance rehabilitation post-stroke.”
  • NIH/NINDS R01 NS111234, McPherson (PI): “Intraspinal microstimulation for multi-modal rehabilitation.” 
  • Craig H. Neilsen Fnd. SCIRTS 460399, Danziger (PI) and McPherson (Co-I): “Post-SCI bladder reflex conditioning with pelvic neuromodulation.”
Completed
  • Coulter Foundation SEED Grant, McPherson (multi-PI): “Non-invasive decoding of neuromuscular activity for rehabilitation and prosthetic control”
  • NIH/NICHD K12HD073945, McPherson (PI): “Spinal stimulation for neuropathic pain.”
  • Coulter Foundation SEED Grant, McPherson (multi-PI): “Exploring Neural Contributions to Aortic Valve Function and Disease”
  • NIH/NICHD R01 HD079076-01A1, Elliott (PI): “Neuromuscular mechanisms underlying poor recovery from whiplash injuries.”
  • Raymond and Beverly Sackler Foundation, McPherson (PI): “Development of flexible, biocompatible electrode arrays for chronic stimulation of the central nervous system following neurological injury.”
  • NIH /NINDS R01 NS054269, Dewald (PI): “Monoaminergic drive and discoordination following stroke.”