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CXCR4-Binding Positron Emission Tomography Tracers Link Monocyte Recruitment and Endothelial Injury in Murine Atherosclerosis.

Baba O, Huang LH, Elvington A, Szpakowska M, Sultan D, Heo GS, Zhang X, Luehmann H, Detering L, Chevigne A, Liu Y, Randolph GJ.Arterioscler Thromb Vasc Biol. 2020 Dec 17:ATVBAHA120315053. doi: 10.1161/ATVBAHA.120.315053. Online ahead of print.PMID: 33327748

Delineating the Role of Macrophages in Cardiovascular Disease: How Specific Do We Need to Be?

Liu Y, Gropler RJ.Circ Cardiovasc Imaging. 2020 Oct;13(10):e011605. doi: 10.1161/CIRCIMAGING.120.011605. Epub 2020 Oct 20.PMID: 33076697 No abstract available.

Targeted PET Imaging of Chemokine Receptor 2-Positive Monocytes and Macrophages in the Injured Heart.

Heo GS, Bajpai G, Li W, Luehmann HP, Sultan DH, Dun H, Leuschner F, Brody SL, Gropler RJ, Kreisel D, Lavine KJ, Liu Y.J Nucl Med. 2021 Jan;62(1):111-114. doi: 10.2967/jnumed.120.244673. Epub 2020 May 22.PMID: 32444372


CCR2 Positron Emission Tomography for the Assessment of Abdominal Aortic Aneurysm Inflammation and Rupture Prediction.

English SJ, Sastriques SE, Detering L, Sultan D, Luehmann H, Arif B, Heo GS, Zhang X, Laforest R, Zheng J, Lin CY, Gropler RJ, Liu Y.Circ Cardiovasc Imaging. 2020 Mar;13(3):e009889. doi: 10.1161/CIRCIMAGING.119.009889. Epub 2020 Mar 13.PMID: 32164451


Acute Rodent Tolerability, Toxicity, and Radiation Dosimetry Estimates of the S1P1-Specific Radioligand [11C]CS1P1.

Liu H, Laforest R, Gu J, Luo Z, Jones LA, Gropler RJ, Benzinger TLS, Tu Z.Mol Imaging Biol. 2020 Apr;22(2):285-292. doi: 10.1007/s11307-019-01380-z.PMID: 31165387

In preparation for USA Food and Drug Administration (FDA) approval of [(11)C]CS1P1 for human use, an acute biodistribution study in mice and an acute tolerability and toxicity evaluation in rats were conducted. …

Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors.

Tangadanchu VKR, Jiang H, Yu Y, Graham TJA, Liu H, Rogers BE, Gropler R, Perlmutter J, Tu Z.Eur J Med Chem. 2020 Nov 15;206:112713. doi: 10.1016/j.ejmech.2020.112713. Epub 2020 Aug 8.PMID: 32919113

In vivo Characterization of Four 18F-Labeled S1PR1 Tracers for Neuroinflammation.

Liu H, Luo Z, Gu J, Jiang H, Joshi S, Shoghi KI, Zhou Y, Gropler RJ, Benzinger TLS, Tu Z.Mol Imaging Biol. 2020 Oct;22(5):1362-1369. doi: 10.1007/s11307-020-01514-8.PMID: 32602083

Galuminox: Preclinical validation of a novel PET tracer for non-invasive imaging of oxidative stress in vivo.

Sivapackiam J, Liao F, Zhou D, Shoghi KI, Gropler RJ, Gelman AE, Sharma V. Redox biology. 2020 October;37:101690. PubMed PMID: 33039825; PubMed Central
PMCID: PMC7648173; DOI: 10.1016/j.redox.2020.101690.

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