PET-RTRC Seminar Speaker | Uwe Haberkorn, MD

Uwe Haberkorn, MD | Heidelberg University | August 31, 2021 @ 12:00pm CDT | “Design and problems of tumor targeting tracers”

Technological advances in molecular biology and biotechnology are increasingly used for the development of new tumor targeting tracers. In oncology, major progress has recently been achieved with peptidic and small molecule compounds. This relies on the identification and validation of new target structures in close conjunction with the application of new techniques for the development of new biocompatible molecules. These are based on either rational design or high throughput methods such as phage and ribosome display. Their further evaluation and optimization consists in the characterization of the structure-function relationships and subsequent improvement with respect to binding, internalization and biodistribution of corresponding analogues. The concept will be shown for display techniques using peptide libraries and rational design of a radiopharmaceutical targeting the fibroblast activation protein (FAP).

PET-RTRC Hosts First Meeting

The PET Radiotracer Translation and Resource Center’s (PET-RTRC) nationwide network of leaders and collaborators gathered at the School of Medicine campus on April 25 for the center’s first annual meeting. The event, which included a mini poster session, highlighted the PET-RTRC’s primary research projects.