Publications

Click here for the most up-to-date list of publications

Dorando HK, Mutic EC, Tomaszewski KL, Tian L, Stefanov MK, Quinn CC, Veis DJ, Wardenburg JB, Musiek AC, Mehta-Shah N, Payton JE. 2024. bioRxiv. LAIR1 prevents excess inflammatory tissue damage in S. aureus skin infection and Cutaneous T-cell Lymphoma. doi:10.1101/2024.06.13.598864
Dorando HK, Mutic EC, Li JY, Perrin EP, Wurtz M, Quinn CC, Payton JE. LPS and type I&II interferons have opposing effects on epigenetic regulation of LAIR1 expression in mouse and human macrophages. J Leuk Biol. accepted 2023. J Leuk Biol. 2024 Feb 23;115(3):547-564. doi: 10.1093/jleuko/qiad148. PMID: 38011310
Jingjing Pei, Nina Beri, Angela J. Zou, Jared Andrews, Philipp Hubel, Valter Bergant, Rebecca D. Andrews, Kathleen C. F. Sheehan, Andreas Pichlmair, Gaya K. Amarasinghe, Jacqueline E. Payton†, and Daisy W. Leung†. Human Respiratory Syncytial Virus Non-Structural Protein NS1 enters the nucleus to modulate gene transcription. Cell Reports 2021 Oct 12;37(2):109803. doi: 10.1016/j.celrep.2021.109803. PMID: 34644581
Andrews JM, Pyfrom SC, Schmidt JA, Koues OI, Kowalewski RA, Grams NR, Sun JJ, Berman LR, Duncavage EJ, Lee Y-S, Cashen AF, Oltz EM, Payton JE. Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers. EBioMedicine. Sept. 2021; 71: 103559. ePub ahead of print. https://doi.org/10.1016/j.ebiom.2021.103559. PMID: 34461601
Pyfrom SC, Quinn CC, Dorando HK, Luo H, and Payton JE. BCALM (AC099524.1) is a human B lymphocyte-specific lncRNA that modulates B cell receptor-mediated calcium signaling. Journal of Immunology. Aug 1;205(3):595-607. Epub June 22, 2020 doi: 10.4049/jimmunol.2000088. PMID: 32571842
Andrews JM, Schmidt JA, Carson KR, Musiek AC, Mehta-Shah N, Payton JE. Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma. EBioMedicine. 2019 Aug;46:170-183. doi: 10.1016/j.ebiom.2019.07.053. Epub 2019 Jul 26. PMID: 31358475; PMCID: PMC6711861.
Andrews JM, Payton JE. Epigenetic dynamics in normal and malignant B cells: die a hero or live to become a villain. Curr Opin Immunol. 2019 Apr;57:15-22. doi: 10.1016/j.coi.2018.09.020. Epub 2018 Oct 17. Review. PubMed PMID: 30342313; PubMed Central PMCID: PMC6470061.
Pyfrom SC, Luo H, Payton JE. PLAIDOH: a novel method for functional prediction of long non-coding RNAs identifies cancer-specific LncRNA activities. BMC Genomics. 2019 Feb 15;20(1):137. doi: 10.1186/s12864-019-5497-4. PubMed PMID: 30767760; PubMed Central PMCID: PMC6377765.
Christopher MJ, Petti AA, Rettig MP, Miller CA, Chendamarai E, Duncavage EJ, Klco JM, Helton NM, O’Laughlin M, Fronick CC, Fulton RS, Wilson RK, Wartman LD, Welch JS, Heath SE, Baty JD, Payton JE, Graubert TA, Link DC, Walter MJ, Westervelt P, Ley TJ, DiPersio JF. Immune Escape of Relapsed AML Cells after Allogeneic Transplantation. N Engl J Med.2018 Dec 13;379(24):2330-2341. doi: 10.1056/NEJMoa1808777. Epub 2018 Oct 31. PubMed PMID: 30380364; PubMed Central PMCID: PMC6322675.
Andrews JM, El-Alawi M, Payton JE. Genotify: Fast, lightweight gene lookup and summarization. J Open Source Softw.2018;3(28). doi: 10.21105/joss.00885. Epub 2018 Aug 15. PubMed PMID: 31080942; PubMed Central PMCID: PMC6510020.
Gascoyne RD, Nadel B, Pasqualucci L, Fitzgibbon J, Payton JE, Melnick A, Weigert O, Tarte K, Gribben JG, Friedberg JW, Seymour JF, Cavalli F, Zucca E. Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015. Hematol Oncol.2017 Dec;35(4):397-407. doi: 10.1002/hon.2411. Epub 2017 Apr 4. Review. PubMed PMID: 28378425.
Morales AJ, Carrero JA, Hung PJ, Tubbs AT, Andrews JM, Edelson BT, Calderon B, Innes CL, Paules RS, Payton JE, Sleckman BP. A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages. 2017 Mar 31;6. doi: 10.7554/eLife.24655. PubMed PMID: 28362262; PubMed Central PMCID: PMC5409825.
Huang Y, Koues OI, Zhao JY, Liu R, Pyfrom SC, Payton JE, Oltz EM. cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer Independent. Cell Rep. 2017 Mar 21;18(12):2918-2931. doi: 10.1016/j.celrep.2017.02.067. PubMed PMID: 28329684; PubMed Central PMCID: PMC5393904.
Spencer DH, Russler-Germain DA, Ketkar S, Helton NM, Lamprecht TL, Fulton RS, Fronick CC, O’Laughlin M, Heath SE, Shinawi M, Westervelt P, Payton JE, Wartman LD, Welch JS, Wilson RK, Walter MJ, Link DC, DiPersio JF, Ley TJ. CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression. 2017 Feb 23;168(5):801-816.e13. doi: 10.1016/j.cell.2017.01.021. Epub 2017 Feb 16. PubMed PMID: 28215704; PubMed Central PMCID: PMC5328582.
Luo H, Schmidt JA, Lee YS, Oltz EM, Payton JE. Targeted epigenetic repression of a lymphoma oncogene by sequence-specific histone modifiers induces apoptosis in DLBCL. Leuk Lymphoma. 2017 Feb;58(2):445-456. doi: 10.1080/10428194.2016.1190973. Epub 2016 Jun 7. PubMed PMID: 27268204; PubMed Central PMCID: PMC5206989.
Griffith M, Griffith OL, Krysiak K, Skidmore ZL, Christopher MJ, Klco JM, Ramu A, Lamprecht TL, Wagner AH, Campbell KM, Lesurf R, Hundal J, Zhang J, Spies NC, Ainscough BJ, Larson DE, Heath SE, Fronick C, O’Laughlin S, Fulton RS, Magrini V, McGrath S, Smith SM, Miller CA, Maher CA, Payton JE, Walker JR, Eldred JM, Walter MJ, Link DC, Graubert TA, Westervelt P, Kulkarni S, DiPersio JF, Mardis ER, Wilson RK, Ley TJ. Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia. Exp Hematol. 2016 Jul;44(7):603-13. doi: 10.1016/j.exphem.2016.04.011. Epub 2016 May 13. PubMed PMID: 27181063; PubMed Central PMCID: PMC4914477.
Raju S, Kretzmer LZ, Koues OI, Payton JE, Oltz EM, Cashen A, Polic B, Schreiber RD, Shaw AS, Markiewicz MA. NKG2D-NKG2D Ligand Interaction Inhibits the Outgrowth of Naturally Arising Low-Grade B Cell Lymphoma In Vivo. J Immunol. 2016 Jun 1; 196(11):4805-13. doi: 10.4049/jimmunol.1501982. Epub 2016 May 2. PubMed PMID: 27183590; PubMed Central PMCID: PMC4875802.
Koues OI, Collins PL, Cella M, Robinette ML, Porter SI, Pyfrom SC, Payton JE, Colonna M, Oltz EM. Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells. 2016 May 19;165(5):1134-1146. doi: 10.1016/j.cell.2016.04.014. Epub 2016 May 5. PubMed PMID: 27156452; PubMed Central PMCID: PMC4874868.
Gu J, Stevens M, Xing X, Li D, Zhang B, Payton JE, Oltz EM, Jarvis JN, Jiang K, Cicero T, Costello JF, Wang T. Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome.G3 (Bethesda). 2016 Apr 7;6(4):973-86. doi: 10.1534/g3.115.025437. PubMed PMID: 26888867; PubMed Central PMCID: PMC4825665.
Bednarski JJ, Pandey R, Schulte E, White LS, Chen BR, Sandoval GJ, Kohyama M, Haldar M, Nickless A, Trott A, Cheng G, Murphy KM, Bassing CH, Payton JE, Sleckman BP. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. J Exp Med. 2016 Feb 8;213(2):209-23. doi: 10.1084/jem.20151048. Epub 2016 Feb 1. PubMed PMID: 26834154; PubMed Central PMCID: PMC4749927.
Liu C, Duffy B, Bednarski JJ, Calhoun C, Lay L, Rundblad B, Payton JE, Mohanakumar T. Maternal T-Cell Engraftment Interferes With Human Leukocyte Antigen Typing in Severe Combined Immunodeficiency. Am J Clin Pathol. 2016 Feb;145(2):251-7. doi: 10.1093/ajcp/aqv079. Epub 2016 Feb 1. PubMed PMID: 26834123; PubMed Central PMCID: PMC4901308.
Koues OI, Oltz EM, Payton JE. Short-Circuiting Gene Regulatory Networks: Origins of B Cell Lymphoma. Trends Genet.2015 Dec;31(12):720-731. doi: 10.1016/j.tig.2015.09.006. Epub 2015 Oct 22. Review. PubMed PMID: 26604030; PubMed Central PMCID: PMC4674374.
Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, Chang GS, Fulton R, O’Laughlin M, Fronick C, Magrini V, Demeter RT, Larson DE, Kulkarni S, Ozenberger BA, Welch JS, Walter MJ, Graubert TA, Westervelt P, Radich JP, Link DC, Mardis ER, DiPersio JF, Wilson RK, Ley TJ. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. 2015 Aug 25;314(8):811-22. doi: 10.1001/jama.2015.9643. PubMed PMID: 26305651; PubMed Central PMCID: PMC4621257.
Koues OI, Kowalewski RA, Chang LW, Pyfrom SC, Schmidt JA, Luo H, Sandoval LE, Hughes TB, Bednarski JJ, Cashen AF, Payton JE, Oltz EM. Enhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma. 2015 Jan 20;42(1):186-98. doi: 10.1016/j.immuni.2014.12.021. Epub 2014 Dec 25. PubMed PMID: 25607463; PubMed Central PMCID: PMC4302272.