link to Nonet lab micropubs
Marom, R., Zhang, B., Washington, M.E., Song, I.-W., Burrage, L.C., Rossi, V.C., Berrier, A.S., Lindsey, A., Lesinski, J., Nonet, M.L., Chen, J., Baldridge, D., Silverman, G.A., Sutton, V.R., Rosenfeld, J.A., Tran, A.A., Hicks, M. J., Murdock, D.R., Dai, H., Weis, M., Jhangiani, S.N., Muzny, D.M., Gibbs, R.A., Richard Caswell, R., Pottinger, C., Cilliers, D., Stals, K., Undiagnosed Diseases Network, Eyre, D., Krakow, D., Schedl, T., Pak, S. C., and B.H. Lee.. Dominant negative variants in KIF5B cause osteogenesis imperfecta via down regulation of mTOR signaling, PLoS Genet 19(11): e1011005. 2023. [Abstract] [PDF]
Pohl F., Germann A.L., Mao J., Hou S., Bakare B., Kong Thoo Lin P., Yates K., Nonet, M.L, Akk G., Kornfeld K. and J.M. Held .  UNC-49 is a redox-sensitive GABAA receptor that regulates the mitochondrial unfolded protein response cell non-autonomously. Sci Adv. 9(44):eadh2584. 2023. [Abstract] [PDF]
M. L. Nonet.  Rapid generation of C. elegans single copy transgenes combining RMCE and drug selection. Genetics 224: iyad072. 2023. [Abstract] [PDF]
M. L. Nonet. Efficient Transgenesis in Caenorhabditis elegans Using Flp Recombinase-Mediated Cassette Exchange. Genetics 215: 902-921. 2020 [Abstract] [PDF]
Sood P., Murthy K., Kumar V., Nonet M.L., Menon G.I., and S. P. Koushika. Cargo crowding at actin-rich regions along axons causes local traffic jams. Traffic 19: 166-181. 2018 [Abstract] [PDF]
Fu B.X., Hansen L.L., Artiles K.L., Nonet M.L., and A. Z. Fire. Landscape of target: guide homology effects on Cas9-mediated cleavage. Nucleic Acids Research, 42: 13778-87. 2014 [Abstract] [PDF]
Luo S., Schaefer A.M., Dour S., and M.L. Nonet. The conserved LIM domain-containing focal adhesion protein ZYX-1 regulates synaptic maintenace in Caenorhaditis elegans. Development, 141: 3922-33. 2014. [Abstract] [PDF]
Zheng Q., Ahlawat S., Schaefer, A.M., Mahoney T., Koushika S., and M.L. Nonet. The vesicle protein SAM-4 regulates the processivity of synaptic vesicle transport. PLoS Genetics, 10: e1004644. 2014. [Abstract] [PDF]
Marcette J., Chen J.J., and M. L. Nonet. The C. elegans microtubule minus end binding homolog PTRN-1 stabilizes synapses and neurites. eLife 3:e01637. 2014. [Abstract] [PDF]
Nonet M.L. A window into domain amplification through Piccolo in teleost fish. G3, 2:1325-1339. 2012. [Abstract] [PDF]
Saifee O., Metz L.B., Nonet M.L. and C.M. Crowder. A gain-of-function mutation in adenylate cyclase confers isoflurane resistance in Caenorhabditis elegans. Anesthesiology, 115:1162-71. 2011.[Abstract] [PDF]
Rosana M., Luo S., Hoover C.M., Miller K., Minniti A., Inestrosa N. and M.L. Nonet. HID-1, a new component of the peptidergic signaling pathway. Genetics, 187:467-83. 2011. [Abstract] [PDF]
Zheng Q., Schaefer A.M. and M.L. Nonet Regulation of C. elegans presynaptic differentiation and neurite branching via a novel signaling pathway initiated by SAM-10. Development, 138:87-96. 2011 [Abstract] [PDF]
Kumar J., Choudhary B.C., Metpally .R, Zheng Q., Nonet M.L., Ramanathan S., Klopfenstein D.R. and S. P. Koushika. The Caenorhabditis elegans Kinesin-3 Motor UNC-104/KIF1A Is Degraded upon Loss of Specific Binding to Cargo. PLoS Genet. 6: e10011200. 2010. [Abstract] [PDF]
Williams P.R., Suzuki S.C., Yoshimatsu T., Lawrence O.T., Waldron S.J., Parsons M.J., Nonet M.L. and R. O. Wong.In vivo development of outer retinal synapses in the absence of glial contact. J. Neurosci., 30:11951-61. 2010. [Abstract] [PDF]
Hadwiger G., Dour S., Arur S., Fox P. and M. L. Nonet. A monoclonal antibody toolkit for C. elegans. Plos One, 5:e10161. 2010. [Abstract] [PDF]
Bounoutas A., Zheng Q., Nonet M.L. and M. Chalfie. mec-15 Encodes an F-box protein required for touch receptor neuron mechanosensation, synapse formation and development. Genetics, 183:607-17. 2009. [Abstract][PDF]
Kural C., Nonet M.L. and P.R. Selvin. FIONA on Caenorhabditis elegans. Biochemistry, 48:4663-4665. 2009. [Abstract] [PDF]
Mahoney T.R., Luo S., Round E.K., Brauner M., Gottschalk A., Thomas J.H., and M. L.Nonet. Intestinal signaling to GABAergic neurons regulates a rhythmic behavior in Caenorhabditis elegans.  PNAS 105:16350-16355. 2008. [Abstract] [PDF]
Gracheva E.O., Hadwiger G., Nonet M.L., amd J.E. Richmond. Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynpatic density.  Neurosci. Lett., 444:137-142. 2008. [Abstract] [PDF]
Campbell, D. S.,  Sydney A. Stringham, S.A.,  Timm, A,  Xiao, T, Baier, H., Nonet, M.L., and C.-B. Chien. Slit1a inhibits retinal ganglion cell arborisation and synaptogenesis via Robo2-dependent and -independent pathways. Neuron 55 :231-245. 2007. [Abstract] [PDF]
Dai, Y., Goncharov, A., Taru, H., Deken, S., Grill, B., Acckley, B., Nonet, M.L., and Jin, Y. SYD-2/Liprin-a organizes presynaptic active zone formation through ELKS. Nature Neuroscience 9:1479-1487. 2006. [Abstract][PDF]
Gracheva E.O., Burdina A.O., Holgado A.M., Berthelot-Grosjean M., Ackley B.D., Hadwiger G, Nonet M.L.,Weimer, R W., and Richmond JE. Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans. PLos Biol 4:1426-1437. 2006 [Abstract] [PDF]
Mahoney T.R., Liu Q., Itoh T., Luo S., Hadwiger G., Vincent R., Wang Z.W., Fukuda M. and Nonet M.L. Regulation of Synaptic Transmission by RAB-3 and RAB-27 in Caenorhabditis elegans. Mol Biol Cell.17:2617-2625. 2006. [Abstract] [PDF]
Lauer J.M., Dalal S, Marz K.E,. Nonet M.L., Hanson P.I. SNARE complex zero layer residues are not critical for NSF-mediated disassembly. J Biol Chem 281:14823-14832. 2006. [Abstract] [PDF]
Deken, S. L, Vincent, R., Hadwiger, G.,Liu Q., Wang, Z.-W., and Nonet M. L . Redundant Localization Mechanisms of RIM and ELKS in C. elegans. J Neurosci. 25:5975-5983. 2005. [Abstract] [PDF]
Liu Q.,Chen, B., Yankova, M., Morest, D.K., Maryon, E., Hand, A. E., Nonet, M. L, and Wang Z.-W. Presynaptic Ryanodine Receptors are Required for Normal Quantal Size at the C. elegans Neuromuscular Junction. J. Neurosci. 25:6745-6754. 2005. [Abstract] [PDF]
Hawasli, A., Saifee, O., Liu, C, Nonet, M. L. and Crowder, C. M. Resistance to volatile Anesthetics by mutations enhancing excitatory neurotransmitter release in Caenorhabditis elegans. Genetics 168:831-844. 2004. [Abstract][PDF]
Koushika, S., Schaefer, A., Vincent, R., Willis, J. Bowerman, B.Nonet, M. L. Mutations in C. elegans cytoplasmic dynein components reveal specificity of neuronal retrograde cargo. J Neurosci 24:3907. 2004. [Abstract] [PDF]
Santi, C.M., Yuan,A., Fawcett, G., Wang, Z.-W., Butler, A., Nonet, M. L., Wei, A., Rojas, P., Salkoff, L. Dissection of K+ currents in Caenorhabditis elegans muscle cells by genetics and RNA interference. PNAS 100:14391-14396. 2003. [Abstract] [PDF]
Weimer, R. M., Richmond J. E., Davis, W. S., Hadwiger, G., Nonet, M. L., Jorgensen E. M. . Defects in synaptic vesicle docking in unc-18 mutants. Nat Neurosci. 6: 1023. 2003 [Abstract] [PDF]
Yuan A., Santi C., Wei A. Wang Z-W,Pollack K, Nonet M, Kaczmarek L, Crowder M, Salkoff L. The Na+-activated K+ channel is encoded by a member of the Slo gene family. Neuron 37:765. 2003. [Abstract] [PDF]
Simmer, F, Tijsterman M, Parrish S, Koushika S, Nonet M, Fire A, Ahringer J, Plasterk R. Loss of the Putative RNA-Directed RNA Polymerase RRF-3 Makes C. elegans Hypersensitive to RNAi. Curr Biol. 12:1317. 2002. [Abstract] [PDF]
Wang, Z.-W., Saifee, O., Nonet, M. L., and L. Salkoff. SLO-1 potassium channels control quantal content of neurotransmitter release at the C. elegans neuromuscular junction. Neuron 32:867-881. 2001. [Abstract] [PDF]
Staunton, J., Ganetzky, B. and Nonet, M. L. Rabphilin potentiates SNARE function independently of rab3. J Neurosci. 21:9255-9564. 2001. [Abstract] [PDF]
Koushika, S.,Richmond, J. E., Hadwiger, G,Weimer, R. M., Jorgensen, E. M. and Nonet, M. L.. A post-docking role for active zone protein Rim. Nat Neurosci. 4 :997-1005. 2001.[Abstract] [PDF]
Zhao, H. and Nonet, M. L. A conserved mechanism of synaptogyrin localization. Mol Biol Cell. 12:2275-2289. 2001. [Abstract] [PDF]
Salkoff, L., Butler, A., Fawcett, G., Kunkel, M., McArdle, C., Paz-y-Mino, G., Nonet, M., Walton, N., Wang, Z.-W., Yuan, A., Wei, A. Evolution tunes the excitability of individual neurons. Neuroscience103:853-859 .2001. [Abstract] [PDF]
Schaefer,A. M. , Hadwiger, G. D. and Nonet, M. L. rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans. Neuron 26:345-56. 2000. [Abstract] [PDF]
Zhao, H. and M. L. Nonet. A retrograde signal is involved in activity-dependent remodeling at a C. elegansneuromuscular junction. Development, 127: 1253-1266. 2000. [Abstract] [PDF]
Nonet, M. L., Holgado, A. M., Brewer,F., Serpe, C. J., Norbeck, B. A., J., H., Wei, L., Hartwieg, E., Jorgensen, E. M., and Alfonso, A. UNC-11, a C. elegans AP180 homolog, Regulates The Size and Protein Composition of Synaptic Vesicles. Mol Biol Cell 10: 2343-2360. 1999. [Abstract] [PDF]
van Swinderen, B., Saifee, O., Shebester, L. D., Robertson, R. S., Nonet, M. L., and Crowder, C. M. A neomorphic syntaxin mutation blocks volatile-anesthetic action in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 96, 2479-2484. 1999. [Abstract] [PDF]
Nonet, M. L. Visualization of synaptic specializations in live C. elegans using synaptic vesicle-GFP protein fusions. J. Neurosci. Methods 89: 33-40. 1999. [Abstract] [PDF]
Saifee, O. Wei, L. and Nonet, M. L. The C. elegans unc-64 gene encodes a syntaxin that interacts genetically with synaptobrevin. Mol. Biol. Cell 9: 1235-1252. 1998. [Abstract] [PDF]
Nonet, M. L., Saifee, O., Zhao, H., Rand, J. B. and Wei, L. Synaptic transmission deficits in C. elegans synaptobrevin mutants. J. Neurosci. 18: 170-180. 1998 [Abstract] [PDF]
Nonet, M.L., Staunton, J., Kilgard, M.P., Fergestad, T, Hartweig, E, Horvitz, H.R., Jorgensen, E. M. and Meyer, B. J. C. elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles. J. Neurosci. 17:8021-8073. 1997 [Abstract] [PDF]
Iwasaki, K., Staunton, J., Saifee, O., Nonet, M. L. and Thomas J . aex-3 encodes a novel regulator of presynaptic activity in C. elegans. Neuron 18:613-622. 1997. [Abstract] [PDF]
Jorgensen, E. M., Hartweig, E, Schuske, K, Nonet, M. L., Jin, Y. and H.R. Horvitz. Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans. Nature 378: 196-199. 1995. [Abstract] [PDF]
Nonet, M. L., K. Grundahl, B. J. Meyer and J. Rand. Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin. Cell 73:1291-1305. 1993 [Abstract] [PDF]
Koleske, A. J., S. Buratowski, M. Nonet, and R. A. Young. A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell 69: 883-894. 1992. [Abstract] [PDF]
Nonet, M. L. and B. J. Meyer. Early aspects of Caenorhabditis elegans sex determination and dosage compensation are regulated by a zinc finger protein. Nature 351: 65-68. 1991. [Abstract] [PDF]
Scafe, R., C. Martin, M. Nonet, S. Podos, S. Okamura, R. A. Young. Conditional mutations occur predominantly in highly conserved residues of RNA polymerase II subunits. Mol. Cell. Biol. 10: 1270-1275. 1990. [Abstract] [PDF]
Scafe, C., M. Nonet, and R. Young. Eukaryotic RNA polymerase II mutants defective in transcription of a subset of genes. Mol. Cell. Biol. 10: 1010-1016. 1990. [Abstract] [PDF]
Nonet, M., R. A. Young. Intragenic and extragenic suppressors of mutations in the hepta-peptide repeat domain of the largest subunit of RNA polymerase II. Genetics 123: 715-724. 1989. [Abstract] [PDF]
Nonet, M., D. Sweetser, and R. Young. Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell 50: 909-915. 1987. [Abstract] [PDF]
Nonet, M., C. Scafe, J. Sexton, and R. Young. Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis. Mol. Cell. Biol. 7: 1602-1611. 1987. [Abstract] [PDF]
Sweetser, D., M. Nonet, and R. Young. Prokaryotic and eukaryotic RNA polymerases have homologous core subunits. Proc. Nat. Acad. Sci. 84: 1192-1196. 1987. [Abstract] [PDF]
Nonet, M., C. C. Marvel, and D. R. Tolan. The hisT-purF region of Escherichia coli K-12 Chromosome: Identification of additional genes of the hisT and purF operons. J. Biol. Chem. 262: 12209-12217. 1987. [Abstract]  [PDF]
updated 11-13-23 by ML Nonet