This page provides resources relevant to the publication “An individual interneuron participates in many kinds of inhibition and innervates much of the mouse visual thalamus” by Josh L Morgan and Jeff W. Lichtman (2020).  Any questions or dataset requests can be addressed to Josh Morgan at jlmorgan@wustl.edu.

Download preprint or see Morgan Lab Publications

Supplementary Movies: Movie 1: Example LIN arbors ;     Movie 2: LIN1 branch type and synapse distribution;     Movie 3: 3D structure of LIN1 glomerulus;     Movie 4: Connectivity of a Trunk Dendrite;    Movie 5: Connectivity of a Targeting Dendrite

The full resolution aligned LGNs1 dataset is available at 2020 Full resolution through BossDB at JUH.

Downloadable resources necessary for replicating or extending the results of  “An individual interneuron participates in many kinds of inhibition and innervates much of the mouse visual thalamus.”:

1.   Acquire serial section data set using WaferMapper

WaferMapper_2.04 through github

2. Align quarter resolution dataset according to     https://arxiv.org/ftp/arxiv/papers/1612/1612.04787.pdf

3. Quarter resolution dataset of LGNs1

2016 quarter resolution data site

4. Load data into  VAST by Daniel Berger

VAST download.  Harvard hosted VAST website

VASTpackage_V1_2_1

5. Segment a great many voxel by hand in VAST.  The following VAST Segmentation files are compatible with the S4 (quarter resolution) VAST volume of LGNs1.

S4_joshm_15+10+06_JM-DB_8.zip

S4_joshm2_17+11+18.zip

S4_joshm3_2017+11+18.zip

S4_joshm4_boutonSizes_2020+01+14.zip

6. Import segmentations into Matlab and analyze using NautilusAnalysis

NautilusAnalysis 4.0 through github