Research

Systems and Synthetic Biology

We aim to understand microbial gene regulatory networks and engineer microbes for addressing energy, environmental, and health issues. Specifically, we are interested in developing synthetic biology tools, constructing genetic circuits, and engineering regulatory RNAs in diverse bacteria. Learn more

Tae Seok Moon

 

 

 

 

Postdoctoral research at MIT and University of California-San Francisco provided Dr. Moon with expertise in the design and construction of genetic circuits. As a graduate student at MIT, he learned how to construct and optimize novel metabolic pathways to produce biochemicals that can replace oil-based chemicals. Combining his research experiences with more than five years experience in the biotechnology industry, he envisions his career as transforming biology research from an “observation” approach to a “synthesis-based engineering” activity to address energy, environment and health issues. Learn more about Dr. Moon

Recent News & Announcements

2021

September

Prof. Moon & the lab are featured at Voice of America. Link

Prof. Moon’s life story and work are featured in Student Life. Link

Prof. Moon gave an invited talk at JBEI.

Prof. Moon gave an invited talk at Central Synthetic Biology Workshop (Northwestern U).

Shri and Stephen join our lab as PhD rotation students. Welcome!

DOE features our plastic upcycling research on its page. Link

The Moon lab project is featured as the top story on 9/7 by UPI. Link

Prof. Moon gave a talk at the 2021 DOE JGI meeting.

August

Prof. Moon gave 4 talks at ACS.

Prof. Moon gave a presentation at the Cold Spring Harbor meeting (Genome Engineering: CRISPR Frontiers).

Prof. Moon is organizing SynBYSS with the kickoff on 8/26. See details under Education & Outreach. Link

Franklin Zhong joins as a Grad student. Welcome!

Andrew Martin joins as an undergrad student. Welcome!

The Moon lab receives a DOE grant for “Developing a consolidated biological process to upcycle plastics” starting September. Link

Prof. Moon visited MIT, Yale U, Boston U, Manus Bio, Synlogic, and Ginkgo to give an invited talk, discuss a startup opportunity, and collaborate.

Dr. Abhijit Manna joins as a postdoc scholar. Welcome!

Puneet Dhatt joins as a Grad student. Welcome!

July

Prof. Moon gave an invited talk at an EPA workshop.

Prof. Moon gave an invited talk at Synlogic.

Prof. Moon serves as an iGEM Grant Committee Member.

EPA Region 7 Administrator Edward Chu visits the Moon lab to give the EPA grant to Prof. Moon and CoPI Kim Parker. Link Link Link

Prof. Moon serves as an MIT Educational Counselor, conducting interviews and writing interview reports for MIT Undergrad Admissions.

The Moon lab receives an EPA grant with CoPI Dr. Parker. Link

Prof. Moon & Dr. Diao give three presentations at Metabolic Engineering 14.

Prof. Moon serves as an Editorial Board Member for Biotechnology Notes.

Prof. Moon serves as a Special Issue Editor for BioDesign Research (AAAS). Link

June

Prof. Moon is chairing and organizing the inaugural Synthetic Biology Young Speaker Series (SynBYSS), a year-long or even longer, weekly event that consists of a short inspiring talk by a global thought or synthetic biology leader, followed by a long talk by a rising star in synthetic biology. See the advertisement under Education & Outreach.

The Moon lab is selected as the winner for the microbiology category of 2021 ATCC Photo Contest! Congrats! We received 1015 votes! See our winning photo under PEOPLE!

Professor Moon gave three presentations at the SEED conference.

Matt and Chenghao join the lab as PhD students. Welcome!

Moon Research Group receives a grant from DOD ONR for “Engineering microbes to control heat production.” Link

Professor Moon participated in 3 EBRC Roadmap Assessment Workshops.

Professor Moon is nominated to join the Engineering Biology Research Consortium (EBRC) Council this fall. Link

Jordan and Joshua join the lab, Welcome!

May

Prof. Moon serves as a member of the Editorial Advisory Board for ACS Synthetic Biology.

Our collaboration work with Prof. Parker is published. Link

Professor Moon gave a talk (virtually) at the USDA NIFA BRAG Meeting.

Austin gave a talk (virtually) at the EBRC Seminar Series.

April

Professor Moon gave a talk (virtually) at the spring EBRC meeting, regarding our neurochemical sensors (provisional patent application).

JinJin gave a poster presentation at the spring EBRC meeting, regarding muconate production using Rhodococcus.

Professor Moon gave an invited talk & a contributed talk (virtually) at the 43rd SIMB-SBFC conference, regarding plastic upcycling (provisional patent application) and lignin valorization.

Rhiannon gave a poster presentation at the 43rd Symposium on Biomaterials, Fuels and Chemicals (SIMB-SBFC) conference, regarding our improved CRISPR interference tool to engineer Rhodococcus opacus.

March

Congratulations to Drew et al. for their paper published:
DM DeLorenzo, J Diao, R Carr, Y Hu and TS Moon. An improved CRISPR interference tool to engineer Rhodococcus opacus. ACS Synth. Biol. Link

Yuxin Tian joined our lab as a rotation student. Welcome!

February

Our alum Tatenda Shopera is among the researchers who developed one of the first vaccines for COVID-19 at Pfizer! He is featured on the news! Link

January

Alden Filko, Matt Lima, and Xinyue Mu joined our lab as rotation students. Welcome all!

2020

December

Tatenda, our lab alum, is part of the Pfizer team that developed one of the first Covid-19 vaccines. We are proud of you, Tatenda! Link

November

Steven Vo joins the group as a PhD student. Welcome!

Cooper Hostetler joins the group as a Graduate Rotation student. Welcome!

October

Congrats, Matt! Matt will serve as the President of the EBRC Student and Postdoc Association starting November, 2020.

September

Steven Vo joins the group as a Graduate Rotation student. Welcome!

Moon Research Group receives a grant from United States Department of Agriculture for “Development of kill-switches for biocontainment of genetically engineered microbes.” Link

August

Professor Moon gave an invited talk (virtually) at Southern Illinois University (Molecular Biology, Microbiology, and Biochemistry Program Seminar Series).

Professor Moon gave an invited talk (virtually) at the Workshop on Biological Control Mechanisms (Army Research Laboratory).

June

Congratulations to Matt and Austin for their paper published: MB Amrofell, AG Rottinghaus and TS Moon. Engineering microbial diagnostics and therapeutics with smart control. Curr. Opin. Biotechnol. 66, 11-17. (2020) Link

All News