Electrochemical synthesis of benzoxazoles from anilides – a new approach to employ amidyl radical intermediates

A novel electrochemical method for the synthesis of benzoxazoles from readily available anilides is reported. Various functionalities are tolerated and good yields can be achieved. By employing common electrode materials and a simple constant current protocol, this method is an attractive new alternative to conventional pathways.

Tile Gieshoff, Anton Kehl, Dieter Schollmeyer, Kevin D. Moeller and Siegfried R. Waldvogel

Chem. Commun.201753, pp 2974-2977

DOI:10.1039/C7CC00927E

Publication Date: 4th February 2017